Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Maria Eugenia Soria"'
Autor:
Meritxell Llorens-Revull, Maria Isabel Costafreda, Angie Rico, Mercedes Guerrero-Murillo, Maria Eugenia Soria, Sofía Píriz-Ruzo, Elena Vargas-Accarino, Pablo Gabriel-Medina, Francisco Rodríguez-Frías, Mar Riveiro-Barciela, Celia Perales, Josep Quer, Silvia Sauleda, Juan Ignacio Esteban, Marta Bes
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254243 (2021)
Background & aimsHCV CD4+ and CD8+ specific T cells responses are functionally impaired during chronic hepatitis C infection. DAAs therapies eradicate HCV infection in more than 95% of treated patients. However, the impact of HCV elimination on immun
Externí odkaz:
https://doaj.org/article/8903af06d6dd4215b78f5bc7dc80815d
Autor:
Meritxell Llorens-Revull, Josep Gregori, Cristina Dopazo, Francisco Rodriguez-Frías, Damir Garcia-Cehic, Maria Eugenia Soria, Qian Chen, Ariadna Rando, Celia Perales, Juan Ignacio Esteban, Josep Quer, Itxarone Bilbao
Publikováno v:
Genes, Vol 12, Iss 11, p 1731 (2021)
Cirrhosis derived from chronic hepatitis C virus (HCV) infection is still a common indication for liver transplantation (LT). Reinfection of the engrafted liver is universal in patients with detectable viral RNA at the time of transplant and causes f
Externí odkaz:
https://doaj.org/article/863aab83ea9e4a9488ac9990d0ff18db
Autor:
Ana I de Ávila, Isabel Gallego, Maria Eugenia Soria, Josep Gregori, Josep Quer, Juan Ignacio Esteban, Charles M Rice, Esteban Domingo, Celia Perales
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164691 (2016)
Lethal mutagenesis is an antiviral approach that consists in extinguishing a virus by an excess of mutations acquired during replication in the presence of a mutagen. Here we show that favipiravir (T-705) is a potent mutagenic agent for hepatitis C v
Externí odkaz:
https://doaj.org/article/7846274008f54ac0a93b86f2bb6a210a
Autor:
Carlos García-Crespo, Lucía Vázquez-Sirvent, Maria Eugenia Soria, Isabel Gallego, Ana Isabel de Ávila, Brenda Martínez-González, Esteban Domingo, Celia Perales
Publikováno v:
Journal of Hepatology. 77:S589-S590
Autor:
Brenda Martínez-González, María Eugenia Soria, Pablo Mínguez, Ramón Lorenzo-Redondo, Llanos Salar-Vidal, Alberto López-García, Mario Esteban-Muñoz, Antoni Durán-Pastor, Pilar Somovilla, Carlos García-Crespo, Ana Isabel de Ávila, Jordi Gómez, Jaime Esteban, Ricardo Fernández-Roblas, Ignacio Gadea, Esteban Domingo, Celia Perales
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionSARS-CoV-2 isolates of a given clade may contain low frequency genomes that encode amino acids or deletions which are typical of a different clade.MethodsHere we use high resolution ultra-deep sequencing to analyze SARS-CoV-2 mutant spect
Externí odkaz:
https://doaj.org/article/2458e84b3aad42eba6e7b16a7f27dfbb
Autor:
Carlos García-Crespo, Irene Francisco-Recuero, Isabel Gallego, Marina Camblor-Murube, María Eugenia Soria, Ana López-López, Ana Isabel de Ávila, Antonio Madejón, Javier García-Samaniego, Esteban Domingo, Aurora Sánchez-Pacheco, Celia Perales
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionCellular epigenetic modifications occur in the course of viral infections. We previously documented that hepatitis C virus (HCV) infection of human hepatoma Huh-7.5 cells results in a core protein-mediated decrease of Aurora kinase B (AUR
Externí odkaz:
https://doaj.org/article/b3cc1a83b8ad4731aee542b53c738838
Autor:
Meritxell Llorens-Revull, Brenda Martínez-González, Josep Quer, Juan Ignacio Esteban, Gonzalo Núñez-Moreno, Pablo Mínguez, Idoia Burgui, Ricardo Ramos-Ruíz, María Eugenia Soria, Angie Rico, Mar Riveiro-Barciela, Silvia Sauleda, María Piron, Irene Corrales, Francesc E. Borràs, Francisco Rodríguez-Frías, Ariadna Rando, Clara Ramírez-Serra, Silvia Camós, Esteban Domingo, Marta Bes, Celia Perales, Maria Isabel Costafreda
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12183 (2023)
MicroRNAs (miRNAs) encapsulated in extracellular vesicles (EVs) are potential diagnostic and prognostic biomarkers. However, discrepancies in miRNA patterns and their validation are still frequent due to differences in sample origin, EV isolation, an
Externí odkaz:
https://doaj.org/article/7aaffc182b1147bb9eecb780ab262283
Autor:
Carlos García-Crespo, Lucía Vázquez-Sirvent, Pilar Somovilla, María Eugenia Soria, Isabel Gallego, Ana Isabel de Ávila, Brenda Martínez-González, Antoni Durán-Pastor, Esteban Domingo, Celia Perales
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
We report a quantification of the decrease of effectiveness of antiviral agents directed to hepatitis C virus, when the agents are added during an ongoing infection in cell culture vs. when they are added at the beginning of the infection. Major dete
Externí odkaz:
https://doaj.org/article/73c6d82bbe8845b18dff3ceda6ce6cbc
SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes
Autor:
Brenda Martínez-González, María Eugenia Soria, Lucía Vázquez-Sirvent, Cristina Ferrer-Orta, Rebeca Lobo-Vega, Pablo Mínguez, Lorena de la Fuente, Carlos Llorens, Beatriz Soriano, Ricardo Ramos, Marta Cortón, Rosario López-Rodríguez, Carlos García-Crespo, Isabel Gallego, Ana Isabel de Ávila, Jordi Gómez, Luis Enjuanes, Llanos Salar-Vidal, Jaime Esteban, Ricardo Fernandez-Roblas, Ignacio Gadea, Carmen Ayuso, Javier Ruíz-Hornillos, Nuria Verdaguer, Esteban Domingo, Celia Perales
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Mutant spectra of RNA viruses are important to understand viral pathogenesis and response to selective pressures. There is a need to characterize the complexity of mutant spectra in coronaviruses sampled from infected patients. In particular
Externí odkaz:
https://doaj.org/article/6d9736d4a3d14394be76e5f75a5176ca
Autor:
Rosario Sabariegos, Ana María Ortega-Prieto, Luis Díaz-Martínez, Ana Grande-Pérez, Carlos García Crespo, Isabel Gallego, Ana I de Ávila, Laura Albentosa-González, María Eugenia Soria, Pablo Gastaminza, Esteban Domingo, Celia Perales, Antonio Mas
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010210 (2022)
In the course of experiments aimed at deciphering the inhibition mechanism of mycophenolic acid and ribavirin in hepatitis C virus (HCV) infection, we observed an inhibitory effect of the nucleoside guanosine (Gua). Here, we report that Gua, and not
Externí odkaz:
https://doaj.org/article/2f919a8f2d6b481da74b22cb86838e32