Neonatal treatment with cyclosporine A restores neurogenesis and spinogenesis in the Ts65Dn model of Down syndrome

Autor: Fiorenza Stagni, Maria Elisa Salvalai, Andrea Giacomini, Marco Emili, Beatrice Uguagliati, Er Xia, Mariagrazia Grilli, Renata Bartesaghi, Sandra Guidi

Publikováno v: Neurobiology of Disease, Vol 129, Iss , Pp 44-55 (2019)

Down syndrome (DS), a genetic condition due to triplication of chromosome 21, is characterized by reduced proliferation of neural progenitor cells (NPCs) starting from early life stages. This defect is worsened by a reduction of neuronogenesis (accom

Externí odkaz: https://doaj.org/article/bf9371e6fdda4661982a2e2384de7173

Neonatal therapy with clenbuterol and salmeterol restores spinogenesis and dendritic complexity in the dentate gyrus of the Ts65Dn model of Down syndrome

Autor: Beatrice Uguagliati, Marie-Claude Potier, Maria Elisa Salvalai, Christelle Albac, Andrea Giacomini, Renata Bartesaghi, Mariagrazia Grilli, Marco Emili, Fiorenza Stagni, Sandra Guidi

Publikováno v: Neurobiology of Disease, Vol 140, Iss, Pp 104874-(2020)

Down syndrome (DS), a neurodevelopmental disorder caused by triplication of chromosome 21, is characterized by intellectual disability. In DS, defective neurogenesis causes an overall reduction in the number of neurons populating the brain and defect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5929e78889cc31489aa2c4a4cfc8f1b1
http://www.sciencedirect.com/science/article/pii/S0969996120301492

Treatment with corn oil improves neurogenesis and cognitive performance in the Ts65Dn mouse model of Down syndrome

Autor: Fiorenza Stagni, Veronica Vidal-Sanchez, Renata Bartesaghi, Sandra Guidi, Maria Elisa Salvalai, Mariagrazia Grilli, Marco Emili, Andrea Giacomini, Carmen Martínez-Cué

Publikováno v: Brain Research Bulletin Volume 140, June 2018, Pages 378-391
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)

Individuals with Down syndrome (DS), a genetic condition due to triplication of Chromosome 21, are characterized by intellectual disability that worsens with age. Since impairment of neurogenesis and dendritic maturation are very likely key determina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcdcd5cf9e7dff5ed54046902dae8323
http://hdl.handle.net/11585/646592

Treatment with kaempferol: A possible tool to restore neurogenesis in Down syndrome?

Autor: B. Uguagliati, Marco Emili, Renata Bartesaghi, Fiorenza Stagni, Andrea Giacomini, Sandra Guidi, Maria Elisa Salvalai, Mariagrazia Grilli

Publikováno v: European Neuropsychopharmacology. 29:S442-S443

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0adac263d6f82c639e5579e9014d598d
https://doi.org/10.1016/j.euroneuro.2018.11.666