Expression of Nonstructural Rotavirus Protein NSP4 Mimics Ca 2+ Homeostasis Changes Induced by Rotavirus Infection in Cultured Cells

Autor: Héctor Rojas, Yuleima Diaz, Franshelle Peña, José L. Zambrano, Olga Carolina Aristimuño, Marie Christine Ruiz, Leiria Salazar, Fabián Michelangeli, Maria Elena Chemello, Fulvia Bartoli, Germain Trugnan, Serge Chwetzoff, Catherine Sapin

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2008, 82 ((22)), pp.11331-43. ⟨10.1128/JVI.00577-08⟩
Journal of Virology, 2008, 82 ((22)), pp.11331-43. ⟨10.1128/JVI.00577-08⟩

Rotavirus infection modifies Ca 2+ homeostasis, provoking an increase in Ca 2+ permeation, the cytoplasmic Ca 2+ concentration ([Ca 2+ ] cyto ), and total Ca 2+ pools and a decrease in Ca 2+ response to agonists. A glycosylated viral protein(s), NSP4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b4ad6ecfe270fc03feb7f30c1676ed
https://doi.org/10.1128/jvi.00577-08

Characterization of a Membrane Calcium Pathway Induced by Rotavirus Infection in Cultured Cells

Autor: Maria Elena Chemello, José Francisco Pérez, Marie Christine Ruiz, Fabián Michelangeli

Publikováno v: Journal of Virology. 73:2481-2490

Some viruses induce changes in membrane permeability during infection. We have shown previously that the porcine strain of rotavirus, OSU, induced an increase in the permeability to Na + , K + , and Ca 2+ during replication in MA104 cells. In this wo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370a6a777364541f754809b969f4f45b
https://doi.org/10.1128/jvi.73.3.2481-2490.1999

Selective depletion of stored calcium by thapsigargin blocks rotavirus maturation but not the cytopathic effect

Autor: Ferdinando Liprandi, Maria Elena Chemello, Fabián Michelangeli, Max Ciarlet, Marie Christine Ruiz

Publikováno v: Journal of Virology. 69:3838-3847

Rotavirus matures inside the endoplasmic reticulum (ER), a site of intracellular calcium storage. Total cell Ca2+ depletion has been shown to impair virus maturation, arresting this process at the membrane-enveloped intermediate form following its bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a0e6fefbd2163878c0dd8c1c385b32
https://doi.org/10.1128/jvi.69.6.3838-3847.1995

Cytotoxicity in MA-104 cells and rumen protozoa of some phytotoxins and their effect on fermentation by faunated and defaunated rumen inocula

Autor: Fabián Michelangeli, Maria Elena Chemello, J. P. Jouany, Y. Papon, Maria Gloria Dominguez-Bello

Publikováno v: Journal of Agricultural and Food Chemistry. 41:2045-2050

Toxic compounds present in plants are an important factor limiting the nutritional use of tropical legumes. This work deals particularly with the toxic nonprotein amino acid analogues mimosine, DOPA, and canavanine and structurally related compounds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a737dc33f692644794b284748236612
https://doi.org/10.1021/jf00035a044

Ca2+ permeability of the plasma membrane induced by rotavirus infection in cultured cells is inhibited by tunicamycin and brefeldin A

Autor: Franshelle Peña, Olga Carolina Aristimuño, Fabián Michelangeli, Marie Christine Ruiz, Yuleima Diaz, Maria Elena Chemello

Publikováno v: Virology. 333(1)

Rotavirus infection of cultured cells induces a progressive increase in plasma membrane permeability to Ca2+. The viral product responsible for this effect is not known. We have used tunicamycin and brefeldin A to prevent glycosylation and membrane t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c65559cbb2a84076bb12f871ff64b75
https://pubmed.ncbi.nlm.nih.gov/15708592