Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maria E. Wilson"'
Autor:
Jane R. Kenny, Mathew Williams, Richard Beasley, A. Mcgregor, Maria E. Wilson, Avi Eliahu, Irene Braithwaite, Matthew R. Durk, Jennifer Tom, Fang Cai, Ryan Owen, Joshua Galanter, Hart S. Dengler, Rui Zhu, Mark Zak, Hubert Chen
Publikováno v:
Journal of Allergy and Clinical Immunology. 148:783-789
Background The Janus kinase (JAK) pathway mediates the activity of many asthma-relevant cytokines, including IL-4 and IL-13. GDC-0214 is a potent, inhaled, small-molecule JAK inhibitor being developed for the treatment of asthma. Objective We sought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5929ba8f48ae2f44a826e35cc263796
https://doi.org/10.1016/j.jaci.2021.02.042
https://doi.org/10.1016/j.jaci.2021.02.042
Autor:
Chin Wong, Thomas Gelzleichter, Junichiro Sonoda, Amos Baruch, Linda Morrow, Suresh Dheerendra, Leslie W. Chinn, Richard Boismenu, Eric Wakshull, Maria E. Wilson, Puneet S. Arora, Shan Chen, Anjali Vaze, Johnny Gutierrez, Nicholas Lewin-Koh
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Fibroblast growth factor 21 (FGF21) controls metabolic organ homeostasis and eating behavior via FGF receptor 1/Klothoβ (FGFR1/KLB) complexes. Here we show that a bispecific anti-FGFR1/KLB agonist antibody, BFKB8488A, mimics the actions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb1e6fc5999a3fd66bc3ad16e368b18
https://doi.org/10.1073/pnas.2012073117
https://doi.org/10.1073/pnas.2012073117
Autor:
Rebecca Kunder, Maria E. Wilson, Hallam Gugelmann, Joshua Galanter, Richard Beasley, Ryan Owen, Matthew R. Durk, Matthew D. Wright, Tracy Staton, Hubert Chen, Avi Eliahu, Yixuan Zou, Irene Braithwaite, Rui Zhu
Publikováno v:
Airway pharmacology and treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4a19a3ada53922d0c6fd37b1ca2fef7
https://doi.org/10.1183/13993003.congress-2021.oa1196
https://doi.org/10.1183/13993003.congress-2021.oa1196
Autor:
Irene Braithwaite, Maria E. Wilson, Richard Beasley, Matthew R. Durk, Ryan Owen, Jane R. Kenny, H. Rardin, Rui Zhu, Jennifer Tom, Joshua Galanter, A. Mcgregor, Huifen Chen, Fang Cai, Mark Zak, Nico Ghilardi, Avi Eliahu
Publikováno v:
B101. NEW BIOLOGICAL TREATMENTS FOR ASTHMA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::312d21118c141f1618f3807f0fe05207
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4272
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4272
Autor:
Mary E. Keir, Johnny Gutierrez, Kenta Yoshida, Rebecca Kunder, Maria E. Wilson, Jordan Mar, Chin Wong, Mark Z. Chen, Nicholas Lewin-Koh
Publikováno v:
Gastroenterology. 160:S-746
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ded2ca40e2659993b56d7a8751d94f4
https://doi.org/10.1016/s0016-5085(21)02495-1
https://doi.org/10.1016/s0016-5085(21)02495-1
Publikováno v:
Proceedings of the National Academy of Sciences. 104:10500-10505
During pancreas development, both the exocrine and endocrine lineages differentiate from a common pool of progenitor cells with similarities to mature pancreatic duct cells. A small set of transcription factors, including Tcf2, Onecut1, and Foxa2, ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33ea890b37d475ad6f4604c1db9e443
https://doi.org/10.1073/pnas.0704054104
https://doi.org/10.1073/pnas.0704054104
Autor:
Yasuhiro Kosaka, Anna Kalousova, Hans Clevers, Michael S. German, Janet Lau, Maria E. Wilson, Juehu Wang, Caroline Mrejen, Katherine Yang, Vasso Episkopou, Francis C. Lynn
Publikováno v:
Diabetes. 54:3402-3409
To investigate the role of the Sry/hydroxymethylglutaryl box (Sox) transcription factors in the development of the pancreas, we determined the expression pattern of Sox factors in the developing mouse pancreas. By RT-PCR, we detected the presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166e89aefc5da1ace5e387c8943f38ca
https://doi.org/10.2337/diabetes.54.12.3402
https://doi.org/10.2337/diabetes.54.12.3402
Autor:
Maria E. Wilson, John E. Blume, John F. Palma, Yun Ping Zhou, Jeffrey D. Johnson, David A. Nothhelfer, Anthony C. Schweitzer, Azadeh Madjidi, John H. Johnson, Charles F. Burant
Publikováno v:
Diabetes. 54:2612-2619
To assess the molecular changes associated with pancreatic β-cell dysfunction occurring during the onset of type 2 diabetes, we profiled pancreatic islet mRNAs from diabetic male and high-fat–fed female Zucker diabetic fatty (ZDF) rats and their n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d2f76765a0858afb4fea34c9adc49a
https://doi.org/10.2337/diabetes.54.9.2612
https://doi.org/10.2337/diabetes.54.9.2612
Publikováno v:
Mechanisms of Development. 115(1-2):171-176
The earliest endocrine cells in the developing pancreas make glucagon and are described as alpha cells. We show here that these cells express islet amyloid polypeptide and prohormone convertase 1/3 (PC1/3), proteins that are not expressed by mature a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f968d4d61f5b473257a4c9d7fc43b51
Publikováno v:
European Journal of Biochemistry. 232:627-632
A negative regulatory element (NRE) is located between positions -279 and -261 relative to the transcription start site of the human insulin gene. The NRE contains at least three distinct overlapping binding sites for several nuclear proteins. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250f11ebb1226533628cccbdaf701b40
https://doi.org/10.1111/j.1432-1033.1995.627zz.x
https://doi.org/10.1111/j.1432-1033.1995.627zz.x