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pro vyhledávání: '"Maria E. Weinberger"'
Autor:
Maria E. Weinberger, Ulrich Kulozik
Publikováno v:
Membranes, Vol 12, Iss 6, p 603 (2022)
Separation of cells from produced biomolecules is a challenging task in many biotechnological downstream operations due to deposit formation of the retained cells, affecting permeation of the target product. Compression and relaxation behavior of cel
Externí odkaz:
https://doaj.org/article/4a1d24ae7e7a4217ac772de4b92703c3
Autor:
Sven Diederichs, Lorenz Bartsch, Julia C Berkmann, Karin Fröse, Jana Heitmann, Caroline Hoppe, Deetje Iggena, Danny Jazmati, Philipp Karschnia, Miriam Linsenmeier, Thomas Maulhardt, Lino Möhrmann, Johannes Morstein, Stella V Paffenholz, Paula Röpenack, Timo Rückert, Ludger Sandig, Maximilian Schell, Anna Steinmann, Gjendine Voss, Jacqueline Wasmuth, Maria E Weinberger, Ramona Wullenkord
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 5, Pp 442-457 (2016)
Abstract Cancer is a disease of the genome caused by oncogene activation and tumor suppressor gene inhibition. Deep sequencing studies including large consortia such as TCGA and ICGC identified numerous tumor‐specific mutations not only in protein
Externí odkaz:
https://doaj.org/article/f493a237e7b24fe5b81baf1eb7e2e60f
Autor:
Ulrich Kulozik, Maria E. Weinberger
Publikováno v:
Food and Bioproducts Processing. 131:136-143
Alternating crossflow filtration is an emerging technology to mitigate fouling in crossflow microfiltration of cell-protein mixtures by periodically reversing the direction of flow. So far, it is understood that the anti-fouling effects are mostly re
Publikováno v:
Biotechnology progressREFERENCES.
Robust cell retention devices are key to successful cell culture perfusion. Currently, tangential flow filtration (TFF) and alternating tangential flow filtration (ATF) are most commonly used for this purpose. TFF, however, suffers from poor fouling
Autor:
Maria E. Weinberger, Ulrich Kulozik
Publikováno v:
Food and Bioproducts Processing. 129:24-33
Alternating tangential flow (ATF) filtration is a cell retention technique of increasing importance in continuous biomanufacturing. Despite its frequent application, the role of flow reversal in fouling mitigation remains unclear this far. We impleme
Autor:
Maria E. Weinberger, Ulrich Kulozik
Publikováno v:
Journal of Membrane Science. 629:119295
The application of pulsatile crossflow is known to mitigate fouling and enhance permeate flux during filtration of simple one-component suspensions. However, previous studies lack a systematic investigation of the effect on pulsation frequency and am
Publikováno v:
International Dairy Journal. 118:105044
The gel formation mechanism of low-pressure casein gels during the filtration of skim milk remains unknown this far. We investigated the prevailing bond types in this gel and correlated these findings with deposit layer properties and filtration perf
Publikováno v:
Fluid Phase Equilibria. 437:23-33
The prediction quality of COSMO-RS for the thermodynamic properties needed for the design of a liquid-liquid chromatographic process was evaluated for systems containing deep eutectic solvents (DES). Therefore activity coefficients, liquid-liquid equ
Publikováno v:
Journal of Chromatography A. 1491:153-158
Tocopherols are a class of molecules with vitamin E activity. Among those, α-tocopherol is the most important vitamin E source in the human diet. The purification of tocopherols involving biphasic liquid systems can be challenging since these vitami
Autor:
Karin Fröse, Miriam Linsenmeier, Julia C. Berkmann, Jana Heitmann, Lino Möhrmann, Gjendine Voss, Philipp Karschnia, Sven Diederichs, Deetje Iggena, Caroline Hoppe, Lorenz Bartsch, Maria E Weinberger, Paula Röpenack, Johannes Morstein, Timo Rückert, Anna Steinmann, Stella V Paffenholz, Ludger Sandig, Ramona Wullenkord, Jacqueline Wasmuth, Danny Jazmati, Maximilian Schell, Thomas Maulhardt
Publikováno v:
Diederichs, S, Bartsch, L, Berkmann, J C, Fröse, K, Heitmann, J, Hoppe, C, Iggena, D, Jazmati, D, Karschnia, P, Linsenmeier, M, Maulhardt, T, Möhrmann, L, Morstein, J, Paffenholz, S V, Röpenack, P, Rückert, T, Sandig, L, Schell, M, Steinmann, A, Voss, G, Wasmuth, J, Weinberger, M E & Wullenkord, R 2016, ' The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations ', EMBO Molecular Medicine, vol. 8, no. 5, pp. 442-57 . https://doi.org/10.15252/emmm.201506055
EMBO Molecular Medicine
EMBO Molecular Medicine
Cancer is a disease of the genome caused by oncogene activation and tumor suppressor gene inhibition. Deep sequencing studies including large consortia such as TCGA and ICGC identified numerous tumor‐specific mutations not only in protein‐coding