Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Maria E. Mycielska"'
Autor:
Barbara Schwertner, George Dahdal, Wolfgang Jagla, Luis Grossmann, Konstantin Drexler, Michael P. Krahn, Katja Evert, Mark Berneburg, Sebastian Haferkamp, Christine Ziegler, Eric K. Parkinson, Grit Zahn, Maria E. Mycielska, Andreas Gaumann
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
We have recently shown that cancer cells of various origins take up extracellular citrate through the plasma membrane citrate carrier (pmCiC), a specific plasma membrane citrate transporter. Extracellular citrate is required to support cancer cell me
Externí odkaz:
https://doaj.org/article/0e8a6ba44376475d8a649d023b9f0b09
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/710e31d77845457ab88afa0fb069c0fc
Autor:
Sebastian Haferkamp, Konstantin Drexler, Marianne Federlin, Hans J. Schlitt, Mark Berneburg, Jerzy Adamski, Andreas Gaumann, Edward K. Geissler, Vadivel Ganapathy, E. Kenneth Parkinson, Maria E. Mycielska
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Cancer cells need excess energy and essential nutrients/metabolites not only to divide and proliferate but also to migrate and invade distant organs for metastasis. Fatty acid and cholesterol synthesis, considered a hallmark of cancer for anabolism a
Externí odkaz:
https://doaj.org/article/c535675aec8b489abe46ee49c300d3a5
Autor:
Maria E. Mycielska, Markus T. J. Mohr, Katharina Schmidt, Konstantin Drexler, Petra Rümmele, Sebastian Haferkamp, Hans J. Schlitt, Andreas Gaumann, Jerzy Adamski, Edward K. Geissler
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
We have recently discovered that cancer cells take up extracellular citrate through plasma membrane citrate transporter (pmCiC) and advantageously use citrate for their metabolism. Citrate uptake can be blocked with gluconate and this results in decr
Externí odkaz:
https://doaj.org/article/94167722af1242ae8c4c8509999316e3
Autor:
Evan H Stanton, Konstantin Drexler, Sebastian Haferkamp, Marianne Federlin, Jerzy Adamski, Wolfgang Buchalla, Andreas Gaumann, Maria E. Mycielska, Vladimir M. Milenkovic, Katrin Jordan, Martin Proescholdt, Edward K. Geissler
Publikováno v:
Current Molecular Medicine. 22:506-513
Abstract: Brain tissue is known to have elevated citrate levels, necessary to regulate ion chelation, neuron excitability, and are also necessary for the supply of necessary energy substrates to neurons. Importantly, citrate also acts as a central su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75af442b579cf710dc2dce5e8af3bf22
https://doi.org/10.2174/1566524021666210302143802
https://doi.org/10.2174/1566524021666210302143802
Autor:
Edward K. Geissler, Peter J. Oefner, Jerzy Adamski, Sven A. Lang, Andreas Gaumann, Christian H. Wetzel, Christine Ziegler, Karl Kunzelmann, Hans J. Schlitt, Vadivel Ganapathy, Christian J. Wachsmuth, Elke Eggenhofer, Gudrun E. Koehl, Alexander Cecil, Moritz Schladt, Margareta Lantow, Gregor M. Madej, Wolfgang Jagla, Vladimir M. Milenkovic, Cornelia Prehn, Katharina Schmidt, Petra Rümmele, Katja Dettmer, Maria E. Mycielska
Krebs cycle activity in the presence of extracellular citrate and absolute citrate levels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33562ad332dd0da3e0d23cbf15bbe656
https://doi.org/10.1158/0008-5472.22419494.v1
https://doi.org/10.1158/0008-5472.22419494.v1
Autor:
Edward K. Geissler, Peter J. Oefner, Jerzy Adamski, Sven A. Lang, Andreas Gaumann, Christian H. Wetzel, Christine Ziegler, Karl Kunzelmann, Hans J. Schlitt, Vadivel Ganapathy, Christian J. Wachsmuth, Elke Eggenhofer, Gudrun E. Koehl, Alexander Cecil, Moritz Schladt, Margareta Lantow, Gregor M. Madej, Wolfgang Jagla, Vladimir M. Milenkovic, Cornelia Prehn, Katharina Schmidt, Petra Rümmele, Katja Dettmer, Maria E. Mycielska
List of metabolites measured with the AbsoluteIDQ® p180 Kit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408231ff14334a296c84657258cda4df
https://doi.org/10.1158/0008-5472.22419476
https://doi.org/10.1158/0008-5472.22419476
Autor:
Edward K. Geissler, Peter J. Oefner, Jerzy Adamski, Sven A. Lang, Andreas Gaumann, Christian H. Wetzel, Christine Ziegler, Karl Kunzelmann, Hans J. Schlitt, Vadivel Ganapathy, Christian J. Wachsmuth, Elke Eggenhofer, Gudrun E. Koehl, Alexander Cecil, Moritz Schladt, Margareta Lantow, Gregor M. Madej, Wolfgang Jagla, Vladimir M. Milenkovic, Cornelia Prehn, Katharina Schmidt, Petra Rümmele, Katja Dettmer, Maria E. Mycielska
Intracellular Ca2+ in the presence of extracellular citrate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a535b0300734e156283b03f831ae8bd8
https://doi.org/10.1158/0008-5472.22419497.v1
https://doi.org/10.1158/0008-5472.22419497.v1
Autor:
Edward K. Geissler, Peter J. Oefner, Jerzy Adamski, Sven A. Lang, Andreas Gaumann, Christian H. Wetzel, Christine Ziegler, Karl Kunzelmann, Hans J. Schlitt, Vadivel Ganapathy, Christian J. Wachsmuth, Elke Eggenhofer, Gudrun E. Koehl, Alexander Cecil, Moritz Schladt, Margareta Lantow, Gregor M. Madej, Wolfgang Jagla, Vladimir M. Milenkovic, Cornelia Prehn, Katharina Schmidt, Petra Rümmele, Katja Dettmer, Maria E. Mycielska
Glycolysis and fatty acid synthesis are highly active in cancer cells through cytosolic citrate metabolism, with intracellular citrate primarily derived from either glucose or glutamine via the tricarboxylic acid cycle. We show here that extracellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55b93db68abae791c8ca94d3e47f4aed
https://doi.org/10.1158/0008-5472.c.6510392.v1
https://doi.org/10.1158/0008-5472.c.6510392.v1
Autor:
Christian Moser, Petra Ruemmele, Sebastian Gehmert, Hedwig Schenk, Marina P Kreutz, Maria E Mycielska, Christina Hackl, Alexander Kroemer, Andreas A Schnitzbauer, Oliver Stoeltzing, Hans J Schlitt, Edward K Geissler, Sven A Lang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 10, Pp 915-925 (2012)
The prognosis of patients suffering from pancreatic cancer is still poor and novel therapeutic options are urgently needed. Recently, the transcription factor signal transducer and activator of transcription 5b (STAT5b) was associated with tumor prog
Externí odkaz:
https://doaj.org/article/0ed9cc9a5766425895d212fc6899a2e6