Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Maria E. Klut"'
Publikováno v:
Infection and Immunity. 69:7793-7799
Bacterial endotoxin or lipopolysaccharide (LPS) is an important causative agent of sepsis. This study determines the expression of defensins NP-2 and NP-5 and the function of polymorphonuclear leukocytes (PMN) in rabbits treated with LPS. PMN functio
Publikováno v:
European Journal of Haematology. 64:114-120
Polymorphonuclear neutrophils (PMN) are vital in host defense against microbial infections. This study provides a flow cytometric method for the quantitative analysis of microbicidal peptides (defensins) in cells of PMN lineage. Rabbit neutrophil pep
Autor:
Stephan F. van Eeden, Takeshi Terashima, James C. Hogg, Jennifer Hards, Dean English, Maria E. Klut
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 20:171-177
Studies from our laboratory have shown that chronic cigarette smoke exposure causes a neutrophilia associated with a shortening of the mean transit time of polymorphonuclear leukocytes (PMN) though the postmitotic pool of the marrow. The present stud
Autor:
James C. Hogg, Mitsushi Okazawa, Kayoko Tanji-Matsuba, Yuji Saito, Shizu Hayashi, Stephan F. van Eeden, Maria E. Klut
Publikováno v:
Circulation. 97:91-98
Background —Previous studies from our laboratory have shown that the expression of L-selectin on polymorphonuclear neutrophils (PMN) decreases as the cell ages in the circulation and that these older PMN have more fragmented DNA and show morphologi
Autor:
Barry Wiggs, Blair Walker, Maleki Daya, Stephan F. van Eeden, Maria E. Klut, Darlene M. Redenbach, Yuko Kitagawa, James C. Hogg
Publikováno v:
Journal of Applied Physiology. 82:1397-1405
Kitagawa, Yuko, Stephan F. Van Eeden, Darlene M. Redenbach, Maleki Daya, Blair A. M. Walker, Maria E. Klut, Barry R. Wiggs, and James C. Hogg. Effect of mechanical deformation on structure and function of polymorphonuclear leukocytes. J. Appl. Physio
Publikováno v:
Microcirculation. 4:369-380
A hallmark of the systemic response to an inflammatory stimulus is the release of polymorphonuclear leukocytes (PMNs) from the bone marrow. This study was designed to measure the release of PMNs from the bone marrow and to determine their sequestrati
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 9:82-89
Previous studies have shown that polymorphonuclear leukocytes (PMN) are delayed in the pulmonary capillaries by the presence of cigarette smoke. To determine if the PMN delayed by smoking are activated, we estimated the in vivo expression of CD11/CD1
Publikováno v:
Experimental gerontology. 37(4)
The elderly are susceptible to infections and show a decline in neutrophil (PMN) functions that are regulated by cytosolic calcium [Ca2+]i. This study measures [Ca2+]i in suspended and adherent PMN of young and elderly individuals by using flow cytom
Publikováno v:
American journal of respiratory and critical care medicine. 163(4)
Interleukin-6 (IL-6) is an important mediator of both the hepatic and the bone marrow components of the acute-phase response. Previous studies from our laboratory have shown that cells released into the circulation from the marrow preferentially sequ
Publikováno v:
Journal of immunological methods. 232(1-2)
Neutrophils are important professional phagocytic cells that provide the host with a first line of defense against acute bacterial and fungal diseases and recurrent, severe or unusual infections are associated with inherited defects of neutrophil fun