Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Maria E. Figueiredo"'
Autor:
Jorge A. Avila, Magdalena Kiprowska, Teneka Jean‐Louis, Patricia Rockwell, Maria E. Figueiredo‐Pereira, Peter A. Serrano
Publikováno v:
Brain and Behavior, Vol 10, Iss 1, Pp n/a-n/a (2020)
Abstract Background Inflammation in the brain is mediated by the cyclooxygenase pathway, which leads to the production of prostaglandins. Prostaglandin (PG) D2, the most abundant PG in the brain, increases under pathological conditions and is spontan
Externí odkaz:
https://doaj.org/article/788e8ab9caf340bda5cc17d943f0a8d3
Autor:
Chuhyon Corwin, Anastasia Nikolopoulou, Allen L. Pan, Mariela Nunez-Santos, Shankar Vallabhajosula, Peter Serrano, John Babich, Maria E. Figueiredo-Pereira
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-18 (2018)
Abstract Background Prostaglandins are products of the cyclooxygenase pathway, which is implicated in Parkinson’s disease (PD). Limited knowledge is available on mechanisms by which prostaglandins contribute to PD neurodegeneration. To address this
Externí odkaz:
https://doaj.org/article/48b9b6e3d06a4b6ba8a87a695ff69d4c
Autor:
Jorge A. Avila, Roseanna M. Zanca, Denis Shor, Nicholas Paleologos, Amber A. Alliger, Maria E. Figueiredo-Pereira, Peter A. Serrano
Publikováno v:
Heliyon, Vol 4, Iss 2 (2018)
Methamphetamine (MA) is an addictive drug with neurotoxic effects on the brain producing cognitive impairment and increasing the risk for neurodegenerative disease. Research has focused largely on examining the neurochemical and behavioral deficits i
Externí odkaz:
https://doaj.org/article/1076a3968560482c83de36ecca100245
Autor:
Argiris A. Talamagas, Spiros Efthimiopoulos, Effie C. Tsilibary, Maria E. Figueiredo-Pereira, Athina K. Tzinia
Publikováno v:
Neurobiology of Disease, Vol 28, Iss 3, Pp 304-315 (2007)
To understand matrix metalloproteinase-9 (MMP-9) involvement in Alzheimer’s disease, we examined mechanisms mediating increased expression of MMP-9 in the presence of Abeta(1–40) and the role of MMP-9 on amyloid precursor protein (APP) processing
Externí odkaz:
https://doaj.org/article/e0d2f2a9e7074cf8816ecaac557dd31e
Publikováno v:
Neurobiology of Disease, Vol 22, Iss 2, Pp 294-301 (2006)
There is clear evidence that an inflammatory reaction is mounted within the CNS following trauma, stroke, infection and seizures, thus augmenting brain damage. Furthermore, chronic inflammation of the CNS is implicated in many neurodegenerative disor
Externí odkaz:
https://doaj.org/article/89fa581e1d9744969a16c8bfea4cc312
Autor:
Osama Chaudry, Kelechi Ndukwe, Lei Xie, Peter A. Serrano, Maria E. Figueiredo-Pereira, Patricia Rockwell
Alzheimer’s disease (AD) is a progressive neurodegenerative disease and is the sixth leading cause of death in the US. AD is more prevalent in females than males. While estrogen provides neuroprotection in females, sex mediated differences in the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd73733e5167c85fd293d440a5458c0f
https://doi.org/10.1101/2022.03.27.485975
https://doi.org/10.1101/2022.03.27.485975
Autor:
Giovanni Oliveros, Charles H Wallace, Osama Chaudry, Qiao Liu, Yue Qiu, Lei Xie, Patricia Rockwell, Maria E Figueiredo-Pereira, Peter A Serrano
Publikováno v:
Brain
Alzheimer’s disease is a multifactorial disease that exhibits cognitive deficits, neuronal loss, amyloid plaques, neurofibrillary tangles and neuroinflammation in the brain. Hence, a multi-target drug would improve treatment efficacy. We applied a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179ff3230abaaea3fe0f55f531b0eb2a
https://pubmed.ncbi.nlm.nih.gov/35411386
https://pubmed.ncbi.nlm.nih.gov/35411386
Autor:
Chaudry O, Maria E. Figueiredo-Pereira, Peter A. Serrano, Rockwell P, Wallace Ch, Liu Q, Oliveros G, Xie L, Qiu Y
Alzheimer’s disease (AD) is a multifactorial disease that exhibits cognitive deficits, neuronal loss, amyloid plaques, neurofibrillary tangles and neuroinflammation in the brain. We developed a multi-scale predictive modeling strategy that integrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8eda08c35e421ef1dbbe86c11533fbb
https://doi.org/10.1101/2021.04.06.438662
https://doi.org/10.1101/2021.04.06.438662
Autor:
Teneka Jean-Louis, Patricia Rockwell, Magdalena Kiprowska, Maria E. Figueiredo-Pereira, Jorge A. Avila, Peter A. Serrano
Publikováno v:
Brain and Behavior
Brain and Behavior, Vol 10, Iss 1, Pp n/a-n/a (2020)
Brain and Behavior, Vol 10, Iss 1, Pp n/a-n/a (2020)
Background Inflammation in the brain is mediated by the cyclooxygenase pathway, which leads to the production of prostaglandins. Prostaglandin (PG) D2, the most abundant PG in the brain, increases under pathological conditions and is spontaneously me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f1a84d49d6d7c84abb8da1a7da393a
https://doi.org/10.1002/brb3.1465
https://doi.org/10.1002/brb3.1465
Publikováno v:
Biochim Biophys Acta Mol Basis Dis
Mitochondrial impairment and calcium (Ca(++)) dyshomeostasis are associated with Parkinson’s disease (PD). When intracellular ATP levels are lowered, Ca(++)-ATPase pumps are impaired causing cytoplasmic Ca(++) to be elevated and calpain activation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc672135696b4f199bf278d27b3adbb
https://europepmc.org/articles/PMC6502656/
https://europepmc.org/articles/PMC6502656/