Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maria E. B. Berstad"'
Autor:
Olav Engebraaten, Christina Yau, Kristian Berg, Elin Borgen, Øystein Garred, Maria E. B. Berstad, Ane S. V. Fremstedal, Angela DeMichele, Laura van ’t Veer, Laura Esserman, Anette Weyergang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Antibody Drug Conjugates (ADCs) are emerging in the field of precision cancer medicine. Here, the authors suggest using endocytosis as a predictive biomarker for response
Externí odkaz:
https://doaj.org/article/e22471ff5b0c4bbbb30060d2218ab799
Publikováno v:
Toxins, Vol 12, Iss 8, p 519 (2020)
Advances in recombinant DNA technology have opened up new possibilities of exploiting toxic proteins for therapeutic purposes. Bringing forth these protein toxins from the bench to the bedside strongly depends on the availability of production method
Externí odkaz:
https://doaj.org/article/59ebbf0a44e94a379f7e91c730368eee
Autor:
Laura van 't Veer, Laura J. Esserman, Øystein Garred, Olav Engebraaten, Maria E B Berstad, Christina Yau, Elin Borgen, Anette Weyergang, Ane Sofie Viset Fremstedal, Angela DeMichele, Kristian Berg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
HER2 is a predictive biomarker for HER2-targeted therapeutics. For antibody–drug conjugates (ADCs; e.g., trastuzumab emtansine (T-DM1)), HER2 is utilized as a transport gate for cytotoxic agents into the cell. ADC biomarkers may therefore be more c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772e45a2f0de058ceab0fc1897c8a893
https://doaj.org/article/e22471ff5b0c4bbbb30060d2218ab799
https://doaj.org/article/e22471ff5b0c4bbbb30060d2218ab799
Publikováno v:
Toxins
Volume 12
Issue 8
Toxins, Vol 12, Iss 519, p 519 (2020)
Volume 12
Issue 8
Toxins, Vol 12, Iss 519, p 519 (2020)
Advances in recombinant DNA technology have opened up new possibilities of exploiting toxic proteins for therapeutic purposes. Bringing forth these protein toxins from the bench to the bedside strongly depends on the availability of production method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2df6a59e33c7f6e55be3853dcb770b5
Autor:
Sebastian Patzke, Maria E B Berstad, Pål Kristian Selbo, Vigdis Sørensen, Kristian Berg, Judith Jing Wen Wong, Ane Sofie Viset Fremstedal, Qian Peng, Anette Weyergang
Publikováno v:
Cancers, Vol 12, Iss 2, p 417 (2020)
Cancers
Volume 12
Issue 2
Cancers
Volume 12
Issue 2
Lysosomal accumulation of sunitinib has been suggested as an underlying mechanism of resistance. Here, we investigated if photochemical internalization (PCI), a technology for cytosolic release of drugs entrapped in endosomes and lysosomes, would act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0387947bd30dd924c7b6d68f0359fe27
https://www.mdpi.com/2072-6694/12/2/417
https://www.mdpi.com/2072-6694/12/2/417
Autor:
Kristian Berg, Michael G. Rosenblum, Ane Sofie Viset Fremstedal, Maria E B Berstad, Ellen Skarpen, Yu Cao, Bente Bull-Hansen, Anette Weyergang, Qian Peng
Publikováno v:
Oncotarget
HER2-targeted therapy has been shown to have limited efficacy in ovarian cancer despite frequent overexpression of this receptor. Photochemical internalization (PCI) is a modality for cytosolic drug delivery, currently undergoing clinical evaluation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2acbf0b92a754d3892eb5350eb2e26
https://doi.org/10.18632/oncotarget.3814
https://doi.org/10.18632/oncotarget.3814
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1820:1849-1858
Background Photochemical internalization (PCI) is a modality for cytosolic release of drugs trapped in endocytic vesicles. The method is based upon photosensitizers localized in the membranes of endocytic vesicles which create membrane rupture upon l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::855c1cd05d30de37b98340ef892cce51
https://doi.org/10.1016/j.bbagen.2012.08.027
https://doi.org/10.1016/j.bbagen.2012.08.027
Autor:
Kristian Berg, Cathrine Elisabeth Olsen, Maria E B Berstad, Anette Weyergang, Pål Kristian Selbo, Bente Bull-Hansen
Publikováno v:
Photochemicalphotobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 14(8)
Resistance to chemotherapy, molecular targeted therapy as well as radiation therapy is a major obstacle for cancer treatment. Cancer resistance may be exerted through multiple different mechanisms which may be orchestrated as observed in multidrug re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b241c920e184e1c0606cc55b2fa54777
https://pubmed.ncbi.nlm.nih.gov/25849953
https://pubmed.ncbi.nlm.nih.gov/25849953
Autor:
Maria E B Berstad, Sebastian Patzke, Ane Sofie Viset Fremstedal, Qian Peng, Lawrence H. Cheung, Kristian Berg, Anette Weyergang, Michael G. Rosenblum
Publikováno v:
Oncogene. 34(44)
The number of epidermal growth factor receptor (EGFR)-targeting drugs in the development for cancer treatment is continuously increasing. Currently used EGFR-targeted monoclonal antibodies and tyrosine kinase inhibitors have specific limitations rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23bd3acf4b7169337e6b495a6357ed5
https://pubmed.ncbi.nlm.nih.gov/25684137
https://pubmed.ncbi.nlm.nih.gov/25684137
Publikováno v:
Lasers in surgery and medicine. 43(7)
Photochemical internalization (PCI) is a method for intracellular delivery of hydrophilic macromolecular drugs with intracellular targets as well as other drugs with limited ability to penetrate cellular membranes. Such drugs enter cells by means of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f8989b2caf3306014827485adf5e45e
https://pubmed.ncbi.nlm.nih.gov/22057500
https://pubmed.ncbi.nlm.nih.gov/22057500