Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Maria E Moreno-Fernandez"'
Autor:
Bandik Föh, Jana Sophia Buhre, Hanna B Lunding, Maria E Moreno-Fernandez, Peter König, Christian Sina, Senad Divanovic, Marc Ehlers
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0266071 (2022)
The microbially-derived short-chain fatty acid butyrate is a central inhibitor of inflammatory innate and adaptive immune responses. Emerging evidence suggests that butyrate induces differentiation of IL-10-producing (IL-10+) regulatory B cells. Howe
Externí odkaz:
https://doaj.org/article/9efba67467ae4398abb40ceecba393f4
Autor:
Daniel A Giles, Maria E Moreno-Fernandez, Traci E Stankiewicz, Monica Cappelletti, Stacey S Huppert, Yoichiro Iwakura, Chen Dong, Shiva K Shanmukhappa, Senad Divanovic
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149783 (2016)
Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease worldwide. While it is well-accepted that inflammation is central to NAFLD pathogenesis, the immune pathway(s) orchestrating disease progression are poorly def
Externí odkaz:
https://doaj.org/article/ef191c9fa60849a687266e2947a58f67
In vitro HIV infection impairs the capacity of myeloid dendritic cells to induce regulatory T cells.
Autor:
Pietro Presicce, Maria E Moreno-Fernandez, Laura K Rusie, Carl Fichtenbaum, Claire A Chougnet
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42802 (2012)
Myeloid dendritic cells (mDCs) are the antigen-presenting cells best capable of promoting peripheral induction of regulatory T cells (Tregs), and are among the first targets of HIV. It is thus important to understand whether HIV alters their capacity
Externí odkaz:
https://doaj.org/article/4d59573832b0443bbe70e32fa3f40818
Autor:
Jessica R. Doll, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Jennifer L. Wayland, Adrienne Wilburn, Benjamin Weinhaus, Claire A. Chougnet, Daniela Giordano, Monica Cappelletti, Pietro Presicce, Suhas G. Kallapur, Nathan Salomonis, Tamara Tilburgs, Senad Divanovic
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112352- (2023)
Summary: Clinical evidence points to a function for B cell-activating factor (BAFF) in pregnancy. However, direct roles for BAFF-axis members in pregnancy have not been examined. Here, via utility of genetically modified mice, we report that BAFF pro
Externí odkaz:
https://doaj.org/article/59d828a84fe34ca5847dca21b989426e
Autor:
Jarren R. Oates, Keisuke Sawada, Daniel A. Giles, Pablo C. Alarcon, Michelle S.M.A. Damen, Sara Szabo, Traci E. Stankiewicz, Maria E. Moreno-Fernandez, Senad Divanovic
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionInflammation is a common unifying factor in experimental models of non-alcoholic fatty liver disease (NAFLD) progression. Recent evidence suggests that housing temperature-driven alterations in hepatic inflammation correlate with exacerba
Externí odkaz:
https://doaj.org/article/1f1bb9be755e44ee861e3cade70d99e3
Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner
Autor:
Maria E. Moreno-Fernandez, Vishakha Sharma, Traci E. Stankiewicz, Jarren R. Oates, Jessica R. Doll, Michelle S. M. A. Damen, Maha A. T. A. Almanan, Claire A. Chougnet, David A. Hildeman, Senad Divanovic
Publikováno v:
Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Background Understanding gender-associated bias in aging and obesity-driven metabolic derangements has been hindered by the inability to model severe obesity in female mice. Methods Here, using chow- or high fat diet (HFD)-feeding regimens a
Externí odkaz:
https://doaj.org/article/7d0c748d3a344ab1a14d117f2eb1e4a9
Autor:
Calvin C. Chan, Isaac T. W. Harley, Paul T. Pfluger, Aurelien Trompette, Traci E. Stankiewicz, Jessica L. Allen, Maria E. Moreno-Fernandez, Michelle S. M. A. Damen, Jarren R. Oates, Pablo C. Alarcon, Jessica R. Doll, Matthew J. Flick, Leah M. Flick, Joan Sanchez-Gurmaches, Rajib Mukherjee, Rebekah Karns, Michael Helmrath, Thomas H. Inge, Stuart P. Weisberg, Sünje J. Pamp, David A. Relman, Randy J. Seeley, Matthias H. Tschöp, Christopher L. Karp, Senad Divanovic
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Interactions between the immune system and adipose tissue contribute to the regulation of body weight, however, the underlying mechanisms remain incompletely understood. Here the authors dissect the role of two structurally and functionally similar i
Externí odkaz:
https://doaj.org/article/1874a0fdf3df440c914731f67be8205d
Autor:
Calvin C. Chan, Michelle S. M. A. Damen, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Monica Cappelletti, Pablo C. Alarcon, Jarren R. Oates, Jessica R. Doll, Rajib Mukherjee, Xiaoting Chen, Rebekah Karns, Matthew T. Weirauch, Michael A. Helmrath, Thomas H. Inge, Senad Divanovic
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
White adipose inflammation can occur in obesity and is at least in part mediated by inflammatory immune cells. Here the authors show that the Type I Interferon/Interferon alpha-beta receptor axis promotes an inflammatory, glycolysis associated adipoc
Externí odkaz:
https://doaj.org/article/d7769e000a41416a858c145b467956f7
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100937- (2021)
Summary: Isolation of viable immune cells from human tissues is critical for the characterization of cellular and molecular processes underlying disease pathogenesis. Here, we describe protocols for the isolation of highly viable immune cells from li
Externí odkaz:
https://doaj.org/article/acf24b2036b647e8bf83ce1ccd47cba9
Autor:
Alyssa L. Thomas, Pablo C. Alarcon, Senad Divanovic, Claire A. Chougnet, David A. Hildeman, Maria E. Moreno-Fernandez
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Aging and obesity are two conditions characterized by chronic, low-grade inflammation. While both conditions are also associated with dysfunctional immune responses, the shared and distinct underlying mechanisms are just starting to be uncovered. In
Externí odkaz:
https://doaj.org/article/071eff6706d84f6c9f411082e6cb5b5d