Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Maria E, Engel"'
Autor:
Steven M, Bryce, Derek T, Bernacki, Jeffrey C, Bemis, Richard A, Spellman, Maria E, Engel, Maik, Schuler, Elisabeth, Lorge, Pekka T, Heikkinen, Ulrike, Hemmann, Véronique, Thybaud, Sabrina, Wilde, Nina, Queisser, Andreas, Sutter, Andreas, Zeller, Melanie, Guérard, David, Kirkland, Stephen D, Dertinger
Publikováno v:
Environmental and molecular mutagenesis. 58(3)
We previously described a multiplexed in vitro genotoxicity assay based on flow cytometric analysis of detergent-liberated nuclei that are simultaneously stained with propidium iodide and labeled with fluorescent antibodies against p53, γH2AX, and p
Autor:
William C, Gunther, Stephanie L, Coffing, Donna A, Dickinson, Maria E, Engel, Ronald D, Fiedler, Susan D, O'Lone, Kelley E, Sanok, Catherine J, Thiffeault, Thomas J, Shutsky, Maik J, Schuler, Krista L, Dobo
Publikováno v:
Environmental and molecular mutagenesis. 55(6)
Ethyl methanesulfonate (EMS) was evaluated as part of the validation effort for the rat Pig-a mutation assay and compared with other well-established in vivo genotoxicity endpoints. Male Sprague-Dawley (SD) rats were given a daily dose of 0, 6.25, 12