Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Maria Dolors Fernández"'
Autor:
Maria Antonia Buil, Manuel Fuentes Ferrer, Sonia Espinosa, Francisca Antón, Jordi Castro, Josep M. Huerta, Jorge Beleta, Manuel López, Mònica Córdoba, Dolors Vilella, Montserrat Miralpeix, Gaspar Casals, Maria Prat, Victor Segarra, Maria Dolors Fernández, Hamish Ryder, Marisa González, Alvaro Cardenas, Juan Manuel Monleón, Israel Ramos, Laia Tort, Amadeu Gavaldà
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1736-1741
Novel quaternary ammonium derivatives of (3R)-quinuclidinyl amides have been identified as potent M3 muscarinic antagonists with a long duration of action in an in vivo model of bronchoconstriction. The synthesis, structure-activity relationships and