Factors for severe outcomes following SARS-CoV-2 infection in people with cystic fibrosis in Europe

Autor: Andreas Jung, Annalisa Orenti, Fiona Dunlevy, Elina Aleksejeva, Egil Bakkeheim, Vladimir Bobrovnichy, Siobhán B. Carr, Carla Colombo, Harriet Corvol, Rebecca Cosgriff, Géraldine Daneau, Deniz Dogru, Pavel Drevinek, Andrea Dugac Vukic, Isabelle Fajac, Alice Fox, Stojka Fustik, Vincent Gulmans, Satenik Harutyunyan, Elpis Hatziagorou, Irena Kasmi, Hana Kayserová, Elena Kondratyeva, Uroš Krivec, Halyna Makukh, Kestutis Malakauskas, Edward F. McKone, Meir Mei-Zahav, Isabelle de Monestrol, Hanne Vebert Olesen, Rita Padoan, Tsitsino Parulava, Maria Dolores Pastor-Vivero, Luísa Pereira, Guergana Petrova, Andreas Pfleger, Liviu Pop, Jacqui G. van Rens, Milan Rodic´, Marc Schlesser, Valérie Storms, Oxana Turcu, Lukasz Woz´niacki, Panayiotis Yiallouros, Anna Zolin, Damian G. Downey, Lutz Naehrlich

Publikováno v: ERJ Open Research, Vol 7, Iss 4 (2021)

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in people with cystic fibrosis (pwCF) can lead to severe outcomes. Methods In this observational study, the European Cystic Fibrosis Society Patient Registry collected

Externí odkaz: https://doaj.org/article/3e2becbd44ec4bf582d17021b6083a88

Elevated levels of the complement activation product C4d in bronchial fluids for the diagnosis of lung cancer.

Autor: Daniel Ajona, Cristina Razquin, Maria Dolores Pastor, Maria Jose Pajares, Javier Garcia, Felipe Cardenal, Michael Fleischhacker, Maria Dolores Lozano, Javier J Zulueta, Bernd Schmidt, Ernest Nadal, Luis Paz-Ares, Luis M Montuenga, Ruben Pio

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0119878 (2015)

Molecular markers in bronchial fluids may contribute to the diagnosis of lung cancer. We previously observed a significant increase of C4d-containing complement degradation fragments in bronchoalveolar lavage (BAL) supernatants from lung cancer patie

Externí odkaz: https://doaj.org/article/9263d1efdaef4fd2abcbacbaa9f63d45

Prospective multicentre study of experience in real-world clinical practice in monitoring reported outcome measures (PROMs) of patient with a diagnosis of psoriatic and/or spondyloarthritis and initiating treatment with secukinumab

Autor: Garrido, Juan José Lerma ^*, Pérez, Antonio Gracia, Torres, Antonio Pérez, Cid, Amalia Rueda, Almela, Clara Molina, Cubillo, María Dolores Pastor, Fernández, Cristina Campos, Trull, Isabel Balaguer, Carmona, Loreto, Catalá, Javier Calvo

Publikováno v: In Reumatología clínica (English Edition) January 2022 18(1):25-29

Impact of Heat Shock Protein 90 Inhibition on the Proteomic Profile of Lung Adenocarcinoma as Measured by Two-Dimensional Electrophoresis Coupled with Mass Spectrometry

Autor: Álvaro Quintanal-Villalonga, Maria Dolores Pastor, Ángela Marrugal, Laura Ojeda, Irene Ferrer, Amancio Carnero, Sonia Molina-Pinelo, Luis Paz-Ares

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Cells
Cells, Vol 8, Iss 8, p 806 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Volume 8
Issue 8

Heat shock protein 90 (HSP90) is an important chaperone in lung adenocarcinoma, with relevant protein drivers such as EGFR (epidermal growth factor receptor) and EML4-ALK (echinoderm microtubule-associated protein-like protein4 fused to anaplastic ly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f1164920b0ff9181206e6ace2666f4
http://hdl.handle.net/20.500.12105/8205

Identification of Oxidative Stress Related Proteins as Biomarkers for Lung Cancer and Chronic Obstructive Pulmonary Disease in Bronchoalveolar Lavage

Autor: Ana Nogal, Amparo Sanchez-Gastaldo, Beatriz Romero-Romero, Maria Dolores Mediano, Ricardo Melendez, Rocio Garcia-Carbonero, Sonia Molina-Pinelo, Luis Paz-Ares, José Luis López-Campos, Amancio Carnero, Maria Dolores Pastor

Publikováno v: International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 3440-3455 (2013)
International Journal of Molecular Sciences; Volume 14; Issue 2; Pages: 3440-3455
International Journal of Molecular Sciences
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla

Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) commonly coexist in smokers, and the presence of COPD increases the risk of developing LC. Cigarette smoke causes oxidative stress and an inflammatory response in lung cells, which in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee2cf2233ccede235cb946300665d0e
http://www.mdpi.com/1422-0067/14/2/3440