Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Maria D. Ganfornina"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Teaching methodologies promoting active learning result in higher-order knowledge application, a desirable outcome in health disciplines like Physiology. Flipped-classroom (FC) promotes active learning and engagement in the classroom. A
Externí odkaz:
https://doaj.org/article/456c67a8946641d7a24dc481b98122b8
Autor:
Miriam Corraliza-Gomez, Beatriz Bendito, David Sandonis-Camarero, Jorge Mondejar-Duran, Miguel Villa, Marta Poncela, Jorge Valero, Diego Sanchez, Maria D. Ganfornina
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Microglial cells are recognized as very dynamic brain cells, screening the environment and sensitive to signals from all other cell types in health and disease. Apolipoprotein D (ApoD), a lipid-binding protein of the Lipocalin family, is required for
Externí odkaz:
https://doaj.org/article/86d47cd7cf3c4dda814810c74a552358
Autor:
Diego Sanchez, Maria D. Ganfornina
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Apolipoprotein D is a chordate gene early originated in the Lipocalin protein family. Among other features, regulation of its expression in a wide variety of disease conditions in humans, as apparently unrelated as neurodegeneration or breast cancer,
Externí odkaz:
https://doaj.org/article/51ad5921e33f4351be8dcf18a3b6834d
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The protein family of Lipocalins is ubiquitously present throughout the tree of life, with the exception of the phylum Archaea. Phylogenetic relationships of chordate Lipocalins have been proposed in the past based on protein sequence similarities, b
Externí odkaz:
https://doaj.org/article/e8878d0bd60341fabc1c378e0cfe19ab
Autor:
Raquel Pascua-Maestro, Miriam Corraliza-Gomez, Cristian Fadrique-Rojo, Maria D. Ledesma, Edward H. Schuchman, Diego Sanchez, Maria D. Ganfornina
Publikováno v:
Neurobiology of Disease, Vol 144, Iss , Pp 105046- (2020)
Lysosomal Storage Diseases (LSD) are genetic diseases causing systemic and nervous system dysfunction. The glia-derived lipid binding protein Apolipoprotein D (ApoD) is required for lysosomal functional integrity in glial and neuronal cells, ensuring
Externí odkaz:
https://doaj.org/article/045e9b13583b44bf92c1b1cd9b79c70a
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The fruit fly compound eye is a premier experimental system for modeling human neurodegenerative diseases. The disruption of the retinal geometry has been historically assessed using time-consuming and poorly reliable techniques such as histology or
Externí odkaz:
https://doaj.org/article/b36f1ac8e1694298ae587a0ce2a2b48a
Autor:
Miriam Corraliza-Gómez, Concepción Lillo, Irene Cózar-Castellano, Eduardo Arranz, Diego Sanchez, Maria D. Ganfornina
Publikováno v:
Cells, Vol 11, Iss 2, p 227 (2022)
The insulin-degrading enzyme (IDE) is a zinc-dependent metalloendopeptidase that belongs to the M16A metalloprotease family. IDE is markedly expressed in the brain, where it is particularly relevant due to its in vitro amyloid beta (Aβ)-degrading ac
Externí odkaz:
https://doaj.org/article/58c23eea4d6e4546ba43300b3f5a16b4
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
A proper lipid management is paramount for a healthy brain. Lipid homeostasis alterations are known to be causative or risk factors for many neurodegenerative diseases, or key elements in the recovery from nervous system injuries of different etiolog
Externí odkaz:
https://doaj.org/article/db1e66d391604a408ce00545187c9e47
Autor:
Raquel Pascua-Maestro, Esperanza González, Concepción Lillo, Maria D. Ganfornina, Juan Manuel Falcón-Pérez, Diego Sanchez
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2019)
Extracellular vesicle (EV)-mediated glia-to-neuron communication has been recognized in a growing number of physiological and pathological situations. They transport complex sets of molecules that can be beneficial or detrimental for the receiving ce
Externí odkaz:
https://doaj.org/article/c84815cefb4d4e508120b2e6392061e6
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname
UVaDOC. Repositorio Documental de la Universidad de Valladolid
Producción Científica
Accumulated evidence points to the lipocalin apolipoprotein D (ApoD), one of the few genes consistently upregulated upon brain ageing and neurodegeneration, as an endogenous controller of the redox state of cellular and e
Accumulated evidence points to the lipocalin apolipoprotein D (ApoD), one of the few genes consistently upregulated upon brain ageing and neurodegeneration, as an endogenous controller of the redox state of cellular and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae09cff7d6881b6669fd2c8570329a65
http://hdl.handle.net/10261/282570
http://hdl.handle.net/10261/282570