Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Maria D. Coelho"'
Autor:
AGM Mostofa, Allison Distler, Mark B. Meads, Eva Sahakian, John J. Powers, Alexandra Achille, David Noyes, Gabriela Wright, Bin Fang, Victoria Izumi, John Koomen, Rupal Rampakrishnan, Tuan P. Nguyen, Gabriel De Avila, Ariosto S. Silva, Praneeth Sudalagunta, Rafael Renatino Canevarolo, Maria D. Coelho Siqueira Silva, Raghunandan Reddy Alugubelli, Hongyue A. Dai, Amit Kulkarni, William S. Dalton, Oliver A. Hampton, Eric A. Welsh, Jamie K. Teer, Alexandre Tungesvik, Kenneth L. Wright, Javier Pinilla-Ibarz, Eduardo M. Sotomayor, Kenneth H. Shain, Jason Brayer
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
The clinical utility of histone/protein deacetylase (HDAC) inhibitors in combinatorial regimens with proteasome inhibitors for patients with relapsed and refractory multiple myeloma (MM) is often limited by excessive toxicity due to HDAC inhibitor pr
Externí odkaz:
https://doaj.org/article/7fe4645c54d74f3db9e69957840e8738
Publikováno v:
Infectious Disease Reports, Vol 7, Iss 4 (2015)
Acute acalculous cholecystitis (AAC) is a rare complication of Epstein Barr virus (EBV) infection, with only a few cases reported among pediatric population. This clinical condition is frequently associated with a favorable outcome and, usually, a su
Externí odkaz:
https://doaj.org/article/1dc9aa48f4c5455ab2a722c049c70153
Autor:
John Powers, Tuan P Nguyen, Mark B. Meads, Jason Brayer, David Noyes, Eduardo M. Sotomayor, William S. Dalton, Kenneth L. Wright, Maria D Coelho Siqueira Silva, Allison Distler, Gabriel De Avila, Hongyue A Dai, Eva Sahakian, Oliver A. Hampton, Kenneth H. Shain, Alexandre Tungesvik, John M. Koomen, Praneeth Reddy Sudalagunta, Amit Kulkarni, Raghunandan Reddy Alugubelli, A.G.M. Mostofa, Victoria Izumi, Bin Fang, Ariosto S. Silva, Javier Pinilla-Ibarz, Jamie K. Teer, Eric A. Welsh, Alexandra Achille, Gabriela Wright, Rupal Rampakrishnan, Rafael Renatino Canevarolo
Publikováno v:
JCI Insight
The clinical utility of histone/protein deacetylase (HDAC) inhibitors in combinatorial regimens with proteasome inhibitors for patients with relapsed and refractory multiple myeloma (MM) is often limited by excessive toxicity due to HDAC inhibitor pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb1e08c0bb1e685c7ad4f702d97c4fe
http://europepmc.org/articles/PMC8783683
http://europepmc.org/articles/PMC8783683
Akademický článek
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Akademický článek
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Autor:
Lora Kramer, Yanxia Ning, Mark B. Meads, Praneeth Reddy Sudalagunta, Ariosto S. Silva, Raghunandan Reddy Alugubelli, Rafael Renatino Canevarolo, Maria D Coelho Siqueira Silva, Danny Bui, Liang Zhou, Maciej Kmeiciak, Andrea Ferreira-Gonzalez, Jewel Nkwocha, Steven Grant, Jacquelyn McCarter, Kanika Sharma, Kenneth H. Shain, Yu Zhang, Lin Li, Gabriel De Avila, Cullen Purcell, Rebecca E. Parker, Xiaoyan Hu, Yun Dai
Publikováno v:
Blood Adv
Interactions between the inhibitor of apoptosis protein antagonist LCL161 and the histone deacetylase inhibitor panobinostat (LBH589) were examined in human multiple myeloma (MM) cells. LCL161 and panobinostat interacted synergistically to induce apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f794e4b7280e71f90adb853b6d4a84d1
https://pubmed.ncbi.nlm.nih.gov/34464977
https://pubmed.ncbi.nlm.nih.gov/34464977
Autor:
Rafael Renatino Canevarolo, Constantine N. Logothetis, Christopher L. Cubitt, Mark B. Meads, Amit A. Kulkarni, Maria D Coelho Siqueira Silva, Yosef Landesman, Oliver A. Hampton, Christopher J. Walker, Praneeth Reddy Sudalagunta, Raghunandan Reddy Alugubelli, Gabriel DeAvila, Qi Zhang, Kenneth H. Shain, Ariosto S. Silva
Publikováno v:
Cancer Research. 81:1061-1061
Introduction. Multiple myeloma (MM) is an all but incurable plasma cell malignancy without predictive biomarkers for approved therapies. Selinexor (SELI), a nuclear export inhibitor targeting exportin 1 (XPO1), is approved with dexamethasone (DEX) wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::100ca1f328cc71b6ad55642a83e45ce3
https://doi.org/10.1158/1538-7445.am2021-1061
https://doi.org/10.1158/1538-7445.am2021-1061
Akademický článek
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Autor:
Mark B. Meads, Maria D Coelho Siqueira Silva, Dimple A. Modi, Gabriel De Avila, Jeremy A. Ross, Qi Zhang, Monica Motwani, Jason Harb, Praneeth Reddy Sudalagunta, Raghunandan Reddy Alugubelli, Oliver A. Hampton, Kenneth H. Shain, Melissa Mitchell, Rafael Renatino-Canevarolo, Ariosto S. Silva, Christopher L. Cubitt, Amit Kulkarni, Hongyue Dai, Xin Lu
Publikováno v:
Blood. 136:49-50
Introduction: Despite some long-term remissions, eventual drug resistance in most patients remains a critical obstacle in the treatment of multiple myeloma (MM). The development of new drugs/drug combinations with novel mechanisms of action are neede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f59d9c1b9a7f1e23353e0f41c51e63c1
https://doi.org/10.1182/blood-2020-134924
https://doi.org/10.1182/blood-2020-134924
Autor:
Christopher L. Cubitt, Constantine N. Logothetis, Gabriel De Avila, Rafael Renatino-Canevarolo, Amit Kulkarni, Maria D Coelho Siqueira Silva, Ariosto S. Silva, Oliver A. Hampton, Yosef Landesman, Christian Argueta, Qi Zhang, Kenneth H. Shain, Praneeth Reddy Sudalagunta, Raghunandan Reddy Alugubelli, Mark B. Meads
Publikováno v:
Blood. 136:29-30
Introduction. Multiple myeloma (MM) is an incurable plasma cell malignancy with a growing list of anti-MM therapeutics. However, the development of predictive biomarkers has yet to be achieved for nearly all MM therapeutics. Selinexor (SELI), a nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7b479549fea4d2128409bb4c4e8ff5d
https://doi.org/10.1182/blood-2020-140485
https://doi.org/10.1182/blood-2020-140485