Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maria Cujba"'
Autor:
James Williams, Chloe Hurling, Sabrina Munir, Peter Harley, Carolina Barcellos Machado, Ana-Maria Cujba, Mario Alvarez-Fallas, Davide Danovi, Ivo Lieberam, Rocio Sancho, Philip Beales, Fiona M. Watt
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Bardet-Biedl syndrome (BBS) is a ciliopathy with pleiotropic effects on multiple tissues, including the kidney. Here we have compared renal differentiation of iPS cells from healthy and BBS donors. High content image analysis of WT1-expressing kidney
Externí odkaz:
https://doaj.org/article/d171a7913adc46668842c8c82971940f
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101656- (2022)
Summary: Human induced pluripotent stem cells (hiPSCs) and organoids are important for modeling human development and disease in vitro. In this study, we describe a protocol to differentiate hiPSC toward pancreatic progenitor (PP) organoids and beta-
Externí odkaz:
https://doaj.org/article/6e78da5a9a6242bfaa92ef7748d07f91
Autor:
Bénédicte Oulès, Christina Philippeos, Joe Segal, Matthieu Tihy, Matteo Vietri Rudan, Ana-Maria Cujba, Philippe A. Grange, Sven Quist, Ken Natsuga, Lydia Deschamps, Nicolas Dupin, Giacomo Donati, Fiona M. Watt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Although acne vulgaris is the most common human inflammatory skin disease, its pathogenic mechanisms remain incompletely understood. Here the authors show that GATA6 is involved in maintaining homeostasis of the upper pilosebaceous unit of human skin
Externí odkaz:
https://doaj.org/article/a395f4f59bd04303afa07739957724b5
Autor:
John Ong, Maria Paola Serra, Joe Segal, Ana-Maria Cujba, Soon Seng Ng, Richard Butler, Val Millar, Stephanie Hatch, Salman Zimri, Hiroyuki Koike, Karen Chan, Andrew Bonham, Michelle Walk, Ty Voss, Nigel Heaton, Ragai Mitry, Anil Dhawan, Daniel Ebner, Davide Danovi, Hiromitsu Nakauchi, S. Tamir Rashid
Publikováno v:
Stem Cell Reports, Vol 10, Iss 3, Pp 693-702 (2018)
Summary: Use of hepatocytes derived from induced pluripotent stem cells (i-Heps) is limited by their functional differences in comparison with primary cells. Extracellular niche factors likely play a critical role in bridging this gap. Using image-ba
Externí odkaz:
https://doaj.org/article/7c1f980085ad4d33ad10a8f4d8dd7616
Autor:
Dinithi Sumanaweera, Chenqu Suo, Ana-Maria Cujba, Daniele Muraro, Emma Dann, Krzysztof Polanski, Alexander S. Steemers, Woochan Lee, Amanda J. Oliver, Jong-Eun Park, Kerstin B. Meyer, Bianca Dumitrascu, Sarah A. Teichmann
Single-cell data analysis can infer dynamic changes in cell populations, for example across time, space or in response to perturbation. To compare these dynamics between two conditions, trajectory alignment via dynamic programming (DP) optimization i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::332ab57f231f633a9c123b765a34bbbb
https://doi.org/10.1101/2023.03.08.531713
https://doi.org/10.1101/2023.03.08.531713
Autor:
Maximillian Woodall, Ana-Maria Cujba, Kaylee B. Worlock, Katie-Marie Case, Tereza Masonou, Masahiro Yoshida, Krzysztof Polanski, Ni Huang, Rik G. H. Lindeboom, Lira Mamanova, Liam Bolt, Laura Richardson, Samuel Ellis, Machaela Palor, Thomas Burgoyne, Andreia Pinto, Dale Moulding, Timothy D. McHugh, Aarash Saleh, Eliz Kilich, Puja Mehta, Chris O’Callaghan, Jie Zhou, Wendy Barclay, Paolo De Coppi, Colin R. Butler, Heloise Vinette, Sunando Roy, Judith Breuer, Rachel C. Chambers, Wendy E. Heywood, Kevin Mills, Robert E. Hynds, Sarah A. Teichmann, Kerstin B. Meyer, Marko Z. Nikolić, Claire M. Smith
Children infected with SARS-CoV-2 rarely progress to respiratory failure, but the risk of mortality in infected people over 85 years of age remains high, despite vaccination and improving treatment options. Here, we take a comprehensive, multidiscipl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d879062a84c842d555af5dd10e4eba88
https://doi.org/10.1101/2023.01.16.524211
https://doi.org/10.1101/2023.01.16.524211
Autor:
Sven R Quist, Philippe Grange, Matthieu Tihy, Lydia Deschamps, Bénédicte Oulès, Joe M. Segal, Giacomo Donati, Ana-Maria Cujba, Fiona M. Watt, Christina Philippeos, Matteo Vietri Rudan, Ken Natsuga, Nicolas Dupin
Publikováno v:
Nature Communications
Nature Communications, Vol. 11, No 1 (2020) P. 5067
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications, Vol. 11, No 1 (2020) P. 5067
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Although acne is the most common human inflammatory skin disease, its pathogenic mechanisms remain incompletely understood. Here we show that GATA6, which is expressed in the upper pilosebaceous unit of normal human skin, is down-regulated in acne. G
Autor:
Mario Enrique Alvarez Fallas, Sergio Pedraza-Arevalo, Teodora Manea, Rocio Sancho, Ana-Maria Cujba, Christopher Lambert, Rosario Morrugares
Publikováno v:
Molecular and Cellular Endocrinology
Though embryonic pancreas progenitors are well characterised, the existence of stem/progenitor cells in the postnatal mammalian pancreas has been long debated, mainly due to contradicting results on regeneration after injury or disease in mice. Despi
Autor:
Fiona M. Watt, Daria Belokhvostova, Geraldine Jowett, Ana-Maria Cujba, Lucy Marshall, Johanna Prueller, Ieva Berzanskyte
Publikováno v:
The International Journal of Developmental Biology. 62:571-582
The epidermis is the outer covering of the skin and provides a protective interface between the body and the environment. It is well established that the epidermis is maintained by stem cells that self-renew and generate differentiated cells. In this
Autor:
Nistor Ionut, Andra Nastasa, Simona Hogas, Dimitrie Siriopol, Maria Cujba, Bogdan Andries, Elena Morosanu, Mihai Onofriescu, Mihai Beresoae, Mugurel Apetrii, Adrian Covic, Cristina Popa
Publikováno v:
Nephrology Dialysis Transplantation. 34