Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Maria Concetta Miniaci"'
Autor:
Luisa Speranza, Kardelen Dalim Filiz, Pellegrino Lippiello, Maria Grazia Ferraro, Silvia Pascarella, Maria Concetta Miniaci, Floriana Volpicelli
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 1978 (2024)
Stress profoundly affects physical and mental health, particularly when experienced early in life. Early-life stress (ELS) encompasses adverse childhood experiences such as abuse, neglect, violence, or chronic poverty. These stressors can induce long
Externí odkaz:
https://doaj.org/article/5f5af0a10b4a489badfdab9a38cb29b8
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The modulation of dopamine release from midbrain projections to the striatum has long been demonstrated in reward-based learning, but the synaptic basis of aversive learning is far less characterized. The cerebellum receives axonal projectio
Externí odkaz:
https://doaj.org/article/eaa3b2fcf37e469391e38d222e63815f
Autor:
Claudia Cristiano, Eriola Hoxha, Pellegrino Lippiello, Ilaria Balbo, Roberto Russo, Filippo Tempia, Maria Concetta Miniaci
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113870- (2022)
Several studies indicate a relationship between maternal gut microbiota alteration and increased risk of autism spectrum disorders (ASD) in offspring. The possibility of compensating for such metabolic dysfunction at a very early stage of disease via
Externí odkaz:
https://doaj.org/article/b953a93f779b457a84ab85abc62962be
Publikováno v:
Biosensors and Bioelectronics: X, Vol 12, Iss , Pp 100225- (2022)
Dopamine (DA) is an important catecholamine neuromodulator that is present in the brain of mammal, and changes of its level can be related to some neurological diseases such as Parkinson, Huntington and Alzheimer. As a consequence, rapid, cost-effect
Externí odkaz:
https://doaj.org/article/29afcb045131486ca836a2fe16cf1722
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The ability to identify and avoid environmental stimuli that signal danger is essential to survival. Our understanding of how the brain encodes aversive behaviors has been primarily focused on roles for the amygdala, hippocampus (HIPP), prefrontal co
Externí odkaz:
https://doaj.org/article/bee8b933cf9642738a9253a52b877900
Autor:
Eriola Hoxha, Pellegrino Lippiello, Fabio Zurlo, Ilaria Balbo, Rita Santamaria, Filippo Tempia, Maria Concetta Miniaci
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
The role of the cerebellum in Alzheimer’s disease (AD) has been neglected for a long time. Recent studies carried out using transgenic mouse models have demonstrated that amyloid-β (Aβ) is deposited in the cerebellum and affects synaptic transmis
Externí odkaz:
https://doaj.org/article/b8035e4984974265ba88584a083446b0
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Purkinje cell (PC) dysfunction or degeneration is the most frequent finding in animal models with ataxic symptoms. Mutations affecting intrinsic membrane properties can lead to ataxia by altering the firing rate of PCs or their firing pattern. Howeve
Externí odkaz:
https://doaj.org/article/083b669a653e4aefb438970c31952e91
Publikováno v:
F1000Research, Vol 7 (2018)
Egocentric (self-centered) and allocentric (viewpoint independent) representations of space are essential for spatial navigation and wayfinding. Deficits in spatial memory come with age-related cognitive decline, are marked in mild cognitive impairme
Externí odkaz:
https://doaj.org/article/c02ebc72f3154170bed18ab6a11c3e56
Autor:
Eriola Hoxha, Pellegrino Lippiello, Bibiana Scelfo, Filippo Tempia, Mirella Ghirardi, Maria Concetta Miniaci
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
The formation of the complex cerebellar cortical circuits follows different phases, with initial synaptogenesis and subsequent processes of refinement guided by a variety of mechanisms. The regularity of the cellular and synaptic organization of the
Externí odkaz:
https://doaj.org/article/7e7b8169970246e495af5bf2b5b53592
Autor:
Silvia Biggi, Lucia Buccarello, Alessandra Sclip, Pellegrino Lippiello, Noemi Tonna, Cristiano Rumio, Daniele Di Marino, Maria Concetta Miniaci, Tiziana Borsello
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
The c-Jun N-terminal kinase (JNK) is part of a stress signalling pathway strongly activated by NMDA-stimulation and involved in synaptic plasticity. Many studies have been focused on the post-synaptic mechanism of JNK action, and less is known about
Externí odkaz:
https://doaj.org/article/bdb85762c50a4431b3d7a5fde5955af7