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pro vyhledávání: '"Maria Clara Gravielle"'
Autor:
Maria Clara Gravielle
Publikováno v:
Membranes, Vol 11, Iss 486, p 486 (2021)
GABAA receptors are pentameric ion channels that mediate most synaptic and tonic extrasynaptic inhibitory transmissions in the central nervous system. There are multiple GABAA receptor subtypes constructed from 19 different subunits in mammals that e
Autor:
Maria Clara Gravielle
Publikováno v:
Neurochemistry International. 118:96-104
GABAA receptors mediate most of the fast inhibitory transmissions in the central nervous system. These receptors are pentameric complexes that exhibit high structural and pharmacological heterogeneity, as they can be constructed from 19 distinct subu
Autor:
María Florencia Foitzick, Nelsy Beatriz Medina, Maria Clara Gravielle, Lucía Candela Iglesias García
Publikováno v:
Neuroscience Letters. 721:134801
GABAA receptors are targets of different pharmacologically relevant drugs, such as barbiturates, benzodiazepines, and anesthetics. In particular, benzodiazepines are prescribed for the treatment of anxiety, sleep disorders, and seizure disorders. Ben
Publikováno v:
Journal of Neuroscience Research. 92:1054-1061
The use-dependent regulation of the GABAA receptor occurs under physiological, pathological, and pharmacological conditions. Tolerance induced by prolonged administration of benzodiazepines is associated with changes in GABAA receptor function. Chron
Autor:
Maria Clara Gravielle
Chronic benzodiazepine consumption has been limited by the development of tolerance to most of the pharmacological effects of these drugs and dependence. Because GABAA receptors mediate most of the pharmacological effects of benzodiazepines, they pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::685c53c49f2a9f2e879b22bcda2fb8fc
https://doi.org/10.1016/b978-0-12-800634-4.00030-5
https://doi.org/10.1016/b978-0-12-800634-4.00030-5
Autor:
Maria Clara Gravielle
Publikováno v:
Pharmacological research. 109
Benzodiazepines have been used clinically for more than 50 years to treat disorders such as insomnia, anxiety, and epilepsy, as well as to aid muscle relaxation and anesthesia. The therapeutic index for benzodiazepines if very high and the toxicity i
Autor:
David H. Farb, Kathie L. Eagleson, Maria Clara Gravielle, Pat Levitt, L.J. Schlueter McFadyen-Ketchum, Shelley J. Russek
Publikováno v:
Neuroscience. 168:797-810
Disruption of the GABAergic system has been implicated in multiple developmental disorders, including epilepsy, autism spectrum disorder and schizophrenia. The human gene encoding uPAR (PLAUR) has been shown recently to be associated with the risk of
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/8f9a62a2936045088659b8de560b7ec1
Publikováno v:
Neuroscience. 310
The clinical use of benzodiazepines is limited by the development of tolerance to their pharmacological effects. Tolerance to each of the pharmacological actions of benzodiazepines develops at different rates. The aim of this work was to investigate
Autor:
Georgina Valeria Fernández Macedo, María Laura Cladouchos, Silvia Wikinski, Pablo Martín Cassanelli, Laura Sifonios, María Laura Gutiérrez, Maria Clara Gravielle, Laura Inés Giaccardi
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 60
Working memory is a cognitive function serving goal-oriented behavior. In the last decade, working memory training has been shown to improve performance and its efficacy for the treatment of several neuropsychiatric disorders has begun to be examined