Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Maria Christina Fialho de Mello"'
Publikováno v:
Neurochemistry International. 58:767-775
d -aspartate is present in significant concentrations throughout the nervous tissue but its physiological role is still under discussion. Here, we report the process of d -aspartate release in retinal cells. [ 3 H]- d -aspartate release occurs throug
Autor:
Ricardo Augusto de Melo Reis, Patrícia F. Gardino, Rogerio Panizzutti, Regina Célia Cussa Kubrusly, Ana Lucia Marques Ventura, Bernardo Stutz, Maria Christina Fialho de Mello, Fernando G. de Mello
Publikováno v:
Neurochemistry International. 53:63-70
Purified retina glial Müller cells can express the machinery for dopamine synthesis and release when maintained in culture. Dopamine is detected in cell extracts of cultures exposed to its precursor, L-DOPA. A large portion of synthesized dopamine i
Autor:
Maria Christina Fialho de Mello, Ricardo Augusto de Melo Reis, Fernando G. de Mello, Clarissa S. Schitine, Ana Lucia Marques Ventura
Publikováno v:
Neurochemical Research. 33:1466-1474
Müller cells represent the main type of glia present in the retina interacting with most, if not all neurons in this tissue. Müller cells have been claimed to function as optic fibers in the retina delivering light to photoreceptors with minimal di
Autor:
Edna N. Yamasaki, Maria Christina Fialho de Mello, Ricardo Augusto de Melo Reis, Regina Célia Cussa Kubrusly, Clarissa S. Schitine, Fernando G. de Mello
Publikováno v:
Neurotoxicity Research. 12:145-153
GABA is the main inhibitory aminoacid transmitter present in neurons and glial cells. Its uptake is carried out by specific high-affinity Na(+)/Cl (-) dependent transporters (GATs). It has been reported in the past that, in the avian retina, [(3)H]GA
Autor:
Fernando G. de Mello, Ricardo Augusto de Melo Reis, Regina Célia Cussa Kubrusly, Ana Lucia Marques Ventura, Maria Christina Fialho de Mello
Publikováno v:
Brain Research Reviews. 54:181-188
The role of dopamine in the retina has been studied for the last 30 years and there is now increasing evidence that dopamine is used as a developmental signal in the embryonic retina. Dopamine is the main catecholamine found in the retina of most spe
Autor:
Juliana Carrazzoni Borba, Isabela Pereira Henze, Mariana S. Silveira, Patrícia F. Gardino, Regina Célia Cussa Kubrusly, Fernando G. de Mello, Maria Christina Fialho de Mello, Jan Nora Hokoç
Publikováno v:
Developmental Brain Research. 156:193-201
In the chick retina, dopaminergic cells are generated between embryonic days 3 and 7 (E3/E7). However, the expression of tyrosine hydroxylase (TH), the first enzyme in the catecholamine synthetic pathway, is only detected after E11/E12. During the in
Autor:
Dulce Elena Casarini, Fernando G. de Mello, Maria Christina Fialho de Mello, Marília Zaluar P. Guimarães, Regina Célia Cussa Kubrusly, Jan Nora Hokoç, Ana Paula B. Vieira
Publikováno v:
Journal of Neurochemistry. 86:45-54
DOPA decarboxylase (DDC; aromatic-l-amino acid decarboxylase; EC 4.1.1.28) is absent in retinas from 6-day-old chicken embryos (E6) but is expressed in retina of E8 embryos, in the presumptive outer plexiform layer. Thereafter, DDC appears in cell bo
Autor:
Maria Christina Fialho de Mello, Karin da Costa Calaza, Fernando G. de Mello, Patrícia F. Gardino
Publikováno v:
Neurochemical Research. 28:1475-1485
Glutamate and GABA are the major excitatory and inhibitory neurotransmitters in the CNS. In the retina, it has been shown that glutamate and aspartate and their agonists kainate and NMDA promote the release of GABA. In the chick retina, at embryonic
Autor:
Nelson Enrique Loureiro-dos-Santos, Maria Christina Fialho de Mello, Patrícia F. Gardino, Fernando G. de Mello, Ricardo Augusto de Melo Reis, Olga Maria M.S. De Almeida, Regina Célia Cussa Kubrusly
Publikováno v:
Journal of Neurochemistry. 77:1136-1144
Choline acetyltransferase (ChAT) activity was reduced by more than 85% in cultured retina cells after 16 h treatment with 150 µm kainate (T1/2 : 3.5 h). Glutamate, AMPA and quisqualate also inhibited the enzyme in equivalent proportion. Cell lesion
Publikováno v:
British Journal of Pharmacology. 126:1847-1855
1. Dopamine is known to modulate glutamatergic synaptic transmission in the retina and in several brain regions by activating specific G-protein-coupled receptors. We have examined the possibility of a different type of mechanism for this modulation,