Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maria Chiara Barbera"'
Autor:
Antonella Riva, Eray Sahin, Greta Volpedo, Andrea Petretto, Chiara Lavarello, Rossella Di Sapia, Davide Barbarossa, Nasibeh Riahi Zaniani, Ilaria Craparotta, Maria Chiara Barbera, Uğur Sezerman, Annamaria Vezzani, Pasquale Striano, Teresa Ravizza
Publikováno v:
Neurobiology of Disease, Vol 194, Iss , Pp 106469- (2024)
A dysfunctional gut microbiota-brain axis is emerging as a potential pathogenic mechanism in epilepsy, particularly in pediatric forms of epilepsy. To add new insights into gut-related changes in acquired epilepsy that develops early in life, we used
Externí odkaz:
https://doaj.org/article/615d5941d837463282d6de78857b8353
Autor:
Ersilia Varone, Alessandra Decio, Maria Chiara Barbera, Marco Bolis, Laura Di Rito, Federica Pisati, Raffaella Giavazzi, Ester Zito
Endoplasmic reticulum (ER) stress triggers an adaptive response in tumours which fosters cell survival and resilience to stress. Activation of the ER stress response, through its PERK branch, promotes phosphorylation of the α-subunit of the translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7834e2b3bdf7c473d8b19541e1ebf955
https://hdl.handle.net/11576/2703250
https://hdl.handle.net/11576/2703250
Autor:
Michela Chiappa, Federica Guffanti, Alessandra Decio, Alessandro Aliverti, Francesca Ricci, Eugenio Scanziani, Federica Camin, Ilaria Craparotta, Maria Chiara Barbera, Marco Bolis, Maya Ridinger, Giovanna Damia
Publikováno v:
Cancer Research. 82:3237-3237
Background: BRCA1/2 mutant tumors cells are deficient for homologous recombination (HR)-mediated DNA repair and are particularly sensitive to PARP inhibitors (PARPi). PARPi have proved efficacy in breast, ovarian, prostate, and pancreatic cancers, pa
Autor:
Giuseppe La Regina, Romano Silvestri, Antonio Coluccia, Michael C. Edler, Gabriella De Martino, Maria Chiara Barbera, Denise Barrow, Robert Ian Nicholson, Marino Artico, Andrea Brancale, Ernest Hamel, Gabriela Chiosis
Publikováno v:
Journal of Medicinal Chemistry. 49:947-954
Arylthioindoles (ATIs) that possess a 3-methoxyphenylthio or a 3,5-dimethoxyphenylthio moiety at position 2 of the indole ring were effective tubulin assembly inhibitors, but weak inhibitors of MCF-7 cell growth. ATIs bearing a 3-(3,4,5-trimethoxyphe
Autor:
Mohamed Gomaa, Sook Wah Yee, Claire Simons, Ceri Elizabeth Milbourne, Andrea Brancale, Maria Chiara Barbera
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 21:361-369
Homology models of cytochrome P450 RA1 (CYP26A1) were constructed using three human P450 structures, CYP2C8, CYP2C9 and CYP3A4 as templates for the model building. Using MOE software the lowest energy CYP26A1 model was then assessed for stereochemica