Automatic pigmented lesion segmentation through a dermoscopy-guided OCT approach for early diagnosis

Autor: Olga M. Conde, Aintzane Asumendi, Estibaliz Garrote, Cristina López Sarachaga, Maria Celia Morales, Mª Dolores Boyano, Sergio Lage

Publikováno v: Procedings of SPIE, 2019, 10851, 108510K
Photonics in Dermatology and Plastic Surgery, San Francisco, California, USA, 2019
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)

Early diagnosis of pigmented lesions, specially melanoma, is an unmet clinical need that would help to improve patient prognosis. Apart from histopathological biopsy, the only gold standard non-invasive imaging technique during diagnosis is dermatosc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf9de0276f1737d3b6831209bc1d41a
https://doi.org/10.1117/12.2508002

The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family

Autor: Guido Kroemer, Nathanael Larochette, Jean-Luc Perfettini, Aintzane Asumendi, Rosa-Ana Gonzalez-Polo, Patricia Boya, Catherine Brenner, Remy Fagard, Martine Raphael, Aurélien Deniaud, Fanny Baran-Marszak, Jean Feuillard, Bernard Pau, Isabelle Gourdier, Maria Celia Morales, Karine Andreau

Publikováno v: Oncogene. 22(40)

N-(4-hydroxyphenyl)retinamide (4-HPR, fenretinide) is a potent chemopreventive agent whose effect has been suggested to involve apoptosis induction. 4-HPR induces a loss of the mitochondrial transmembrane potential and the mitochondrial release of cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65af22a32077c24549b92eb29a3d1cf2
https://pubmed.ncbi.nlm.nih.gov/13679861