Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Maria Caterina Mione"'
Autor:
Lucia Longhitano, Nunzio Vicario, Daniele Tibullo, Cesarina Giallongo, Giuseppe Broggi, Rosario Caltabiano, Giuseppe Maria Vincenzo Barbagallo, Roberto Altieri, Marta Baghini, Michelino Di Rosa, Rosalba Parenti, Antonio Giordano, Maria Caterina Mione, Giovanni Li Volti
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The tumor microenvironment (TME) plays a pivotal role in establishing malignancy, and it is associated with high glycolytic metabolism and lactate release through monocarboxylate transporters (MCTs). Several lines of evidence suggest that lactate als
Externí odkaz:
https://doaj.org/article/fb35dcd54d6f419bb4ae1b4a42baf9f9
Autor:
Karla Misselbeck, Silvia Parolo, Francesca Lorenzini, Valeria Savoca, Lorena Leonardelli, Pranami Bora, Melissa J. Morine, Maria Caterina Mione, Enrico Domenici, Corrado Priami
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Metabolic syndrome is characterized by complex phenotypes that increases the risk of cardiovascular disease and type 2 diabetes. Here the authors’ integrative network analysis suggests BTK inhibitor ibrutinib to be a promising treatment through its
Externí odkaz:
https://doaj.org/article/f96705c65bfd49bc85730e82b064dab7
Autor:
Aurora Irene Idilli, Emilio Cusanelli, Francesca Pagani, Francesco Berardinelli, Manuel Bernabé, María Luisa Cayuela, Pietro Luigi Poliani, Maria Caterina Mione
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The activation of a telomere maintenance mechanism (TMM) is an essential step in cancer progression to escape replicative senescence and apoptosis. Alternative lengthening of telomeres (ALT) is found in a subset of malignant brain tumors with poor ou
Externí odkaz:
https://doaj.org/article/6bc6d63613bf4f0d8af770922176d738
Autor:
Thomas Dickmeis, Yi Feng, Maria Caterina Mione, Nikolay Ninov, Massimo Santoro, Herman P. Spaink, Philipp Gut
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
In the past years, evidence has emerged that hallmarks of human metabolic disorders can be recapitulated in zebrafish using genetic, pharmacological or dietary interventions. An advantage of modeling metabolic diseases in zebrafish compared to other
Externí odkaz:
https://doaj.org/article/23633791d6ef4a2db7fa7d45ad797fb9
Autor:
Maria Luisa Cayuela, Kathleen B. M. Claes, Miguel Godinho Ferreira, Catarina Martins Henriques, Fredericus van Eeden, Máté Varga, Jeroen Vierstraete, Maria Caterina Mione
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2019)
Cancer is a disease of the elderly, and old age is its largest risk factor. With age, DNA damage accumulates continuously, increasing the chance of malignant transformation. The zebrafish has emerged as an important vertebrate model to study these pr
Externí odkaz:
https://doaj.org/article/7b328a883d234ebb8a28ac3b5b5abbe0
Autor:
Lucia Longhitano, Nunzio Vicario, Stefano Forte, Cesarina Giallongo, Giuseppe Broggi, Rosario Caltabiano, Giuseppe Maria Vincenzo Barbagallo, Roberto Altieri, Giuseppina Raciti, Michelino Di Rosa, Massimo Caruso, Rosalba Parenti, Arcangelo Liso, Federica Busi, Marco Lolicato, Maria Caterina Mione, Giovanni Li Volti, Daniele Tibullo
Publikováno v:
Cancer immunology, immunotherapy : CII. 72(1)
Lactic acidosis has been reported in solid tumor microenvironment (TME) including glioblastoma (GBM). In TME, several signaling molecules, growth factors and metabolites have been identified to induce resistance to chemotherapy and to sustain immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27188425950314f65ba03abb612aa4ea
https://pubmed.ncbi.nlm.nih.gov/35821528
https://pubmed.ncbi.nlm.nih.gov/35821528
Autor:
Jesús García-Castillo, Victoriano Mulero, Francisca Alcaraz-Pérez, Elena Martínez-Balsalobre, David Hernández-Silva, Monique Anchelin-Flageul, Maria Caterina Mione, María L. Cayuela
Telomeres are essential for chromosome protection and genomic stability, and telomerase function is critical to organ homeostasis. Zebrafish has become a useful vertebrate model for understanding the cellular and molecular mechanisms of regeneration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df202dc6c7dc85ad390764347f4feeae
https://doi.org/10.1101/2021.11.15.468592
https://doi.org/10.1101/2021.11.15.468592
Autor:
Rosario Caltabiano, Giuseppe Barbagallo, Michelino Di Rosa, Giovanni Li Volti, Marta Baghini, Nunzio Vicario, Giuseppe Broggi, Antonio Giordano, Cesarina Giallongo, Maria Caterina Mione, Rosalba Parenti, Lucia Longhitano, Daniele Tibullo
Background. Tumor microenvironment (TME) plays a pivotal role in establishing malignancy and it is associated with high glycolytic metabolism and increased lactate production accumulating in TME through monocarboxylate transporters (MCTs). Several li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef62685d13ebf5c6247938cbc5013a29
https://doi.org/10.21203/rs.3.rs-965025/v1
https://doi.org/10.21203/rs.3.rs-965025/v1
Base Editors are emerging as an innovative technology to introduce point mutations in complex genomes. So far, the requirement of an NGG Protospacer Adjacent Motif (PAM) at a suitable position often limits the editing possibility to model human patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec9bd58dbdef3eac613d5e34ceb95949
https://doi.org/10.1101/2021.06.28.450169
https://doi.org/10.1101/2021.06.28.450169
Autor:
Corrado Priami, Melissa J. Morine, Valeria Savoca, Karla Misselbeck, Silvia Parolo, Pranami Bora, Maria Caterina Mione, Francesca Lorenzini, Enrico Domenici, Lorena Leonardelli
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Metabolic syndrome is a pathological condition characterized by obesity, hyperglycemia, hypertension, elevated levels of triglycerides and low levels of high-density lipoprotein cholesterol that increase cardiovascular disease risk and type 2 diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efcbd3c514043059b9992a337bd7123
http://link.springer.com/article/10.1038/s41467-019-13208-z
http://link.springer.com/article/10.1038/s41467-019-13208-z