Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Maria Carmela Speranza"'
Autor:
Antonella De Rosa, Serena Pellegatta, Marco Rossi, Patrizia Tunici, Letizia Magnoni, Maria Carmela Speranza, Federico Malusa, Vincenzo Miragliotta, Elisa Mori, Gaetano Finocchiaro, Annette Bakker
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52113 (2012)
Glioblastoma multiforme (GBM) is among the most deadly cancers. A number of studies suggest that a fraction of tumor cells with stem cell features (Glioma Stem-like Cells, GSC) might be responsible for GBM recurrence and aggressiveness. GSC similarly
Externí odkaz:
https://doaj.org/article/0b1fde6b883c4ea0bb4991517c92c127
Autor:
David A. Reardon, Gordon J. Freeman, Kristen L Jones, Paul Kirschmeier, Prafulla C. Gokhale, Margaret K. Wilkens, Maria Carmela Speranza, Apoorvi Chaudhri, Sarah R. Klein
Blockade of immune cell co-inhibitory receptor PD-1 using monoclonal antibodies (mAbs) allows the development of anti-tumor immunity in various solid tumors and lymphoid malignancies. We recently demonstrated that PD-1 blockade elicits an anti-tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6d7d7b7d9ff4e43f29505a306db596
https://europepmc.org/articles/PMC6217445/
https://europepmc.org/articles/PMC6217445/
Autor:
Maria Carmela Speranza, Silverio Perrotta, Adriana Borriello, Ilaria Caldarelli, Fulvio Della Ragione, Alessia Borgia, Adriana Oliva, Debora Bencivenga, Annunziata Tramontano, Anna Virginia Adriana Pirozzi
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 60:60-72
Bone marrow mesenchymal stromal cells (BM-MSCs) are multipotent cells capable of differentiating toward osteoblatic and adipocytic phenotypes. BM-MSCs play several key roles including bone remodeling, establishment of hematopoietic niche and immune t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ebc7b8ca5351ff159c5cfb5159060b
https://doi.org/10.1016/j.biocel.2014.12.011
https://doi.org/10.1016/j.biocel.2014.12.011
Autor:
Prafulla C. Gokhale, David A. Reardon, Maria Carmela Speranza, Apoorvi Chaudhri, Gordon J. Freeman, Paul Kirschmeier, Kristen L Jones, Sarah R. Klein, Margaret K. Wilkens
Blockade of immune cell co-inhibitory receptor PD-1 using monoclonal antibodies (mAbs) allows the development of anti-tumor immunity in various solid tumors and lymphoid malignancies. We recently demonstrated that PD-1 blockade elicits an anti-tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdaa52fcd9a3fb995cc8499bf9f30b9
https://europepmc.org/articles/PMC5693073/
https://europepmc.org/articles/PMC5693073/
Autor:
Hiroshi Nakashima, Patrick Y. Wen, David A. Reardon, Michał Nowicki, Brian W. Guzik, Maria Carmela Speranza, Laura K. Aguilar, Gordon J. Freeman, Johanna K. Kaufmann, Franz Ricklefs, Xandra O. Breakefield, Ralph Weissleder, Agnieszka Bronisz, Sarah R. Klein, Carmela Passaro, Prisca Obi, Kazue Kasai, Sean E. Lawler, Abdul-Kareem Ahmed, E. Antonio Chiocca, Estuardo Aguilar-Cordova
Background Combined immunotherapy approaches are promising cancer treatments. We evaluated anti-programmed cell death protein 1 (PD-1) treatment combined with gene-mediated cytotoxic immunotherapy (GMCI) performed by intratumoral injection of a prodr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b872b4788715e55b0f00814efef9d6
https://europepmc.org/articles/PMC5777502/
https://europepmc.org/articles/PMC5777502/
Publikováno v:
JAMA oncology. 3(6)
Importance Oncolytic viruses (OVs) are emerging as important agents in cancer treatment. Oncolytic viruses offer the attractive therapeutic combination of tumor-specific cell lysis together with immune stimulation, therefore acting as potential in si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3b7953728bf75bc6e4c24c15a8ad7f
https://pubmed.ncbi.nlm.nih.gov/27441411
https://pubmed.ncbi.nlm.nih.gov/27441411
Autor:
Choi-Fong Cho, Mariano S. Viapiano, Ralph Weissleder, Hakho Lee, Maria Carmela Speranza, Leonard G. Luyt, E. Antonio Chiocca, Fernanda Bononi, Kyungheon Lee, Sean E. Lawler
Publikováno v:
ACS combinatorial science. 18(6)
Molecular targeting using ligands specific to disease markers has shown great promise for early detection and directed therapy. Bead-based combinatorial libraries have served as powerful tools for the discovery of novel targeting agents. Screening pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766b55f5646766e19c17c7c239207383
https://pubmed.ncbi.nlm.nih.gov/27124678
https://pubmed.ncbi.nlm.nih.gov/27124678
Publikováno v:
ILAR journal. 57(1)
After more than two decades of research and development, oncolytic herpes viruses (oHSVs) are moving into the spotlight due to recent encouraging clinical trial data. oHSV and other oncolytic viruses function through direct oncolytic cancer cell-kill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4762040e5b7e2e0427296bec1cb79c5
https://pubmed.ncbi.nlm.nih.gov/27034396
https://pubmed.ncbi.nlm.nih.gov/27034396
Autor:
Michał Nowicki, Sean E. Lawler, Choi-Fong Cho, Prajna Behera, Maria Carmela Speranza, E. Antonio Chiocca
Publikováno v:
Scientific Reports
Glioblastoma is an aggressive, invasive tumor of the central nervous system (CNS). There is a widely acknowledged need for anti-invasive therapeutics to limit glioblastoma invasion. BKM-120 is a CNS-penetrant pan-class I phosphatidyl-inositol-3 kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63e7e5715ffc1d4957314a9ff9ab3d8
http://europepmc.org/articles/PMC4742861
http://europepmc.org/articles/PMC4742861
Autor:
Franco Locatelli, Ilaria Caldarelli, Aide Negri, Debora Bencivenga, Silverio Perrotta, Adriana Oliva, Emanuela Stampone, Adriana Borriello, Bruno Nobili, Maria Carmela Speranza, Saverio Scianguetta, Annunziata Tramontano, Fulvio Della Ragione
Background Iron overload syndromes include a wide range of diseases frequently associated with increased morbidity and mortality. Several organs are affected in patients with iron overload including liver, heart, joints, endocrine glands, and pancrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c2b9842d4866b662c8f3c559fdaa4b
http://hdl.handle.net/11573/1487627
http://hdl.handle.net/11573/1487627