Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Maria Candida Cesta"'
Autor:
Sophie Toya, Sofie Struyf, Luis Huerta, Peter Morris, Elizabeth Gavioli, Enrico Maria Minnella, Maria Candida Cesta, Marcello Allegretti, Paul Proost
Publikováno v:
European Respiratory Review, Vol 33, Iss 173 (2024)
Acute respiratory distress syndrome (ARDS) is a severe form of acute respiratory failure characterised by extensive inflammatory injury to the alveolocapillary barrier leading to alveolar oedema, impaired gas exchange and, ultimately, hypoxaemia nece
Externí odkaz:
https://doaj.org/article/721673d66d084e9fb4f1a041b1d1d1b4
Autor:
Veronica Cocetta, Manuel Zorzi, Stefano Bejor, Maria Candida Cesta, Maria De Pizzol, Jean-Philippe Theurillat, Marcello Allegretti, Andrea Alimonti, Monica Montopoli, Massimo Rugge
Publikováno v:
Life, Vol 14, Iss 9, p 1107 (2024)
Since the beginning of the COVID-19 pandemic, it has been evident that women and young people were less susceptible to severe infections compared to males. In a previous study, we observed a reduced prevalence of SARS-CoV-2 infections in hormonal-dri
Externí odkaz:
https://doaj.org/article/4db01f065acd464298d89a404b99151d
Autor:
Elizabeth Gavioli, Flavio Mantelli, Maria Candida Cesta, Marta Sacchetti, Marcello Allegretti
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 635 (2024)
Nerve growth factor (NGF), the first neurotrophin to be discovered, has a long and eventful research journey with a series of turning points, setbacks, and achievements. Since the groundbreaking investigations led by Nobel Prize winner Rita Levi-Mont
Externí odkaz:
https://doaj.org/article/d884b4c79c3947508662f10af3af0b48
Autor:
Daniela Iaconis, Licia Bordi, Giulia Matusali, Carmine Talarico, Candida Manelfi, Maria Candida Cesta, Mara Zippoli, Francesca Caccuri, Antonella Bugatti, Alberto Zani, Federica Filippini, Laura Scorzolini, Marco Gobbi, Marten Beeg, Arianna Piotti, Monica Montopoli, Veronica Cocetta, Silvia Bressan, Enrico M. Bucci, Arnaldo Caruso, Emanuele Nicastri, Marcello Allegretti, Andrea R. Beccari
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-9 (2022)
Abstract The new coronavirus SARS-CoV-2 is the causative agent of the COVID-19 pandemic, which so far has caused over 6 million deaths in 2 years, despite new vaccines and antiviral medications. Drug repurposing, an approach for the potential applica
Externí odkaz:
https://doaj.org/article/9f7ad91081cf4ba8bb1f706204ee8be2
Autor:
Mara Zippoli, Anna Ruocco, Rubina Novelli, Francesca Rocchio, Martina Sara Miscione, Marcello Allegretti, Maria Candida Cesta, Pier Giorgio Amendola
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Tumor drug resistance is a multifactorial and heterogenous condition that poses a serious burden in clinical oncology. Given the increasing incidence of resistant tumors, further understanding of the mechanisms that make tumor cells able to escape an
Externí odkaz:
https://doaj.org/article/a5c0f02a97804544a38b0e682ab151b6
Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut
Autor:
Michele d’Angelo, Laura Brandolini, Mariano Catanesi, Vanessa Castelli, Cristina Giorgio, Margherita Alfonsetti, Mara Tomassetti, Mara Zippoli, Elisabetta Benedetti, Maria Candida Cesta, Sandro Colagioia, Pasquale Cocchiaro, Annamaria Cimini, Marcello Allegretti
Publikováno v:
Cells, Vol 12, Iss 5, p 728 (2023)
The intestinal barrier is the main contributor to gut homeostasis. Perturbations of the intestinal epithelium or supporting factors can lead to the development of intestinal hyperpermeability, termed “leaky gut”. A leaky gut is characterized by l
Externí odkaz:
https://doaj.org/article/7a889804ed8b45f88df7c91cc1ff6d7a
Autor:
Chiara Sfogliarini, Giovanna Pepe, Arianna Dolce, Sara Della Torre, Maria Candida Cesta, Marcello Allegretti, Massimo Locati, Elisabetta Vegeto
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Beyond the wide use of tamoxifen in breast cancer chemotherapy due to its estrogen receptor antagonist activity, this drug is being assayed in repurposing strategies against a number of microbial infections. We conducted a literature search on the ev
Externí odkaz:
https://doaj.org/article/3d9ed32578de4f07951bcc0f71d5beeb
Autor:
Maria Candida Cesta, Mara Zippoli, Carolina Marsiglia, Elizabeth Marie Gavioli, Flavio Mantelli, Marcello Allegretti, Robert A. Balk
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Severe Acute Respiratory Syndrome Coronavirus—2 (SARS CoV-2) has resulted in the global spread of Coronavirus Disease 2019 (COVID-19) and an increase in complications including Acute Respiratory Distress Syndrome (ARDS). Due to the lack of therapeu
Externí odkaz:
https://doaj.org/article/ce587c888c974e3a8a88e67c44cf11a5
Autor:
Cristina Giorgio, Mara Zippoli, Pasquale Cocchiaro, Vanessa Castelli, Giustino Varrassi, Andrea Aramini, Marcello Allegretti, Laura Brandolini, Maria Candida Cesta
Publikováno v:
Biomedicines, Vol 9, Iss 4, p 399 (2021)
The complement system is a key component of innate immunity since it plays a critical role in inflammation and defense against common pathogens. However, an inappropriate activation of the complement system is involved in numerous disorders, includin
Externí odkaz:
https://doaj.org/article/f755010812924628b49f5b5318d75933
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Chemoattractants control selective leukocyte homing via interactions with a dedicated family of related GPCR. Emerging evidence indicates that the signalling activity of these receptors, as for other GPCR, is influenced by allosteric modulators, whic
Externí odkaz:
https://doaj.org/article/7d99fa7a046149e7b38407df0d5ee956