Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Maria Cancio"'
Autor:
Andrew L. H. Webster, Mathijs A. Sanders, Krupa Patel, Ralf Dietrich, Raymond J. Noonan, Francis P. Lach, Ryan R. White, Audrey Goldfarb, Kevin Hadi, Matthew M. Edwards, Frank X. Donovan, Remco M. Hoogenboezem, Moonjung Jung, Sunandini Sridhar, Tom F. Wiley, Olivier Fedrigo, Huasong Tian, Joel Rosiene, Thomas Heineman, Jennifer A. Kennedy, Lorenzo Bean, Rasim O. Rosti, Rebecca Tryon, Ashlyn-Maree Gonzalez, Allana Rosenberg, Ji-Dung Luo, Thomas S. Carroll, Sanjana Shroff, Michael Beaumont, Eunike Velleuer, Jeff C. Rastatter, Susanne I. Wells, Jordi Surrallés, Grover Bagby, Margaret L. MacMillan, John E. Wagner, Maria Cancio, Farid Boulad, Theresa Scognamiglio, Roger Vaughan, Kristin G. Beaumont, Amnon Koren, Marcin Imielinski, Settara C. Chandrasekharappa, Arleen D. Auerbach, Bhuvanesh Singh, David I. Kutler, Peter J. Campbell, Agata Smogorzewska
Publikováno v:
Nature, 612(7940), 495-502. Nature Publishing Group
Nature
Nature
Fanconi anaemia (FA), a model syndrome of genome instability, is caused by a deficiency in DNA interstrand crosslink repair resulting in chromosome breakage1–3. The FA repair pathway protects against endogenous and exogenous carcinogenic aldehydes4
Autor:
Matt S. Zinter, A. Birgitta Versluys, Caroline A. Lindemans, Madeline Y. Mayday, Gustavo Reyes, Sara Sunshine, Marilynn Chan, Elizabeth K. Fiorino, Maria Cancio, Sabine Prevaes, Marina Sirota, Michael A. Matthay, Sandhya Kharbanda, Christopher C. Dvorak, Jaap J. Boelens, Joseph L. DeRisi
Publikováno v:
Science translational medicine, vol 14, iss 635
Sci Transl Med
Sci Transl Med
Impaired baseline lung function is associated with mortality after pediatric allogeneic hematopoietic cell transplantation (HCT), yet limited knowledge of the molecular pathways that characterize pretransplant lung function has hindered the developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0f1c71ce3004c492889dda61f5b15c
https://escholarship.org/uc/item/42j26013
https://escholarship.org/uc/item/42j26013
Autor:
Andromachi Scaradavou, Richard J. O'Reilly, Jaap Jan Boelens, Farid Boulad, Susan E. Prockop, Barbara Spitzer, Ichelle van Roessel, Andrew L. Kung, Maria Cancio, Kevin J. Curran, Nancy A. Kernan, Elizabeth Klein
Publikováno v:
Cytotherapy
An association between early CD4+ T cell immune reconstitution (CD4+ IR) and survival after T-replete allogeneic hematopoietic cell transplantation (HCT) has been previously reported. Here we report validation of this relationship in a separate cohor
Autor:
Ellen Fraint, Sana Farooki, Elizabeth Klein, Audrey Mauguen, Susan E Prockop, Andromachi Scaradavou, Kevin Curran, Maria Cancio, Barbara Spitzer, Jaap Jan Boelens, Joseph Oved, Andrew Harris, Richard J O'Reilly, Nancy A. Kernan
Publikováno v:
Transplantation and Cellular Therapy. 29:46.e1-46.e6
Poor graft function (PGF) is a life-threatening complication after allogeneic stem cell transplantation (alloSCT). Historically, outcomes of patients with PGF have been very poor, and there are no standardized approaches to treatment. Furthermore, fe
Autor:
Christopher J. Forlenza, Brigitte Senechal, Nancy A. Kernan, Susan E. Prockop, Yasmin Khakoo, David A. Williams, Isabelle Riviere, Peter G. Steinherz, Craig S. Sauter, Jaap Jan Boelens, Michel Sadelain, Lewis B. Silverman, Farid Boulad, Glenn Heller, Richard J. O'Reilly, Victoria Szenes, Jae H. Park, Barbara Spitzer, Neerav Shukla, Andrew L. Kung, Rachel Kobos, Steven P. Margossian, Renier J. Brentjens, Xiuyan Wang, Maria Cancio, Kevin J Curran
Publikováno v:
Blood. 134:2361-2368
Chimeric antigen receptor (CAR) T cells have demonstrated clinical benefit in patients with relapsed/refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL). We undertook a multicenter clinical trial to determine toxicity, feasibility, and respo
Autor:
Andromachi Scaradavou, Richard J. O'Reilly, Maria Cancio, Elizabeth Klein, Barbara Spitzer, Susan E. Prockop, Jaap Jan Boelens, Joannne Torok-Castanza, Audrey Mauguen, Julianne Ruggiero, Nancy A. Kernan, Kevin J. Curran, Farid Boulad, Jennifer Allen
Publikováno v:
Transplantation and Cellular Therapy. 27:S137-S139
Metatranscriptomic Signatures of Lung Function in Pediatric Hematopoietic Cell Transplant Candidates
Autor:
Sara Sunshine, Sabine M.P.J. Prevaes, Marina Sirota, Elizabeth K. Fiorino, Birgitta Versluys, Marilynn Chan, Matt S. Zinter, Joseph L. DeRisi, Gustavo Reyes, Michael A. Matthay, Jaap Jan Boelens, Christopher C. Dvorak, Sandhya Kharbanda, Maria Cancio, Madeline Y Mayday, Caroline A. Lindemans
RationaleImpaired baseline lung function is associated with mortality after allogeneic hematopoietic cell transplantation (HCT). Limited knowledge of the molecular pathways that characterize pre-transplant lung function has hindered the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79ca9b8b4ed50d7aeb632342a0b73b99
https://doi.org/10.1101/2021.09.21.21263910
https://doi.org/10.1101/2021.09.21.21263910
Autor:
Christine Camacho-Bydume, Audrey Mauguen, M. Irene Rodriguez-Sanchez, Elizabeth Klein, Nancy A. Kernan, Susan Prockop, Jaap Jan Boelens, Genovefa A. Papanicolaou, Maria Cancio
Publikováno v:
Cytotherapy
Cytomegalovirus (CMV) reactivation is a significant complication following allogeneic hematopoietic stem cell transplant (HSCT) and affects upwards of 40% of pediatric HSCT patients. Pre-emptive therapy remains the only effective treatment strategy a
Autor:
Sunandini Sridhar, David I. Kutler, Bhuvanesh Singh, Susanne I. Wells, Ji-Dung Luo, Mathijs A. Sanders, Margaret L. MacMillan, Ashlyn-Maree Gonzalez, Lorenzo Bean, Rebecca Tryon, Huasong Tian, Jordi Surrallés, Arleen D. Auerbach, Kevin Hadi, Moonjung Jung, Ralf Dietrich, Matthew M. Edwards, Eunike Velleuer, Krupa R. Patel, Frank X. Donovan, Amnon Koren, Marcin Imielinski, Audrey Goldfarb, Ozgur Rosti, Jeffrey C. Rastatter, Theresa Scognamiglio, John E. Wagner, Andrew L.H. Webster, Maria Cancio, Olivier Fedrigo, Agata Smogorzewska, Jennifer A. Kennedy, Thomas Carrol, Grover C. Bagby, Joel Rosiene, Allana Rosenberg, Thomas Heineman, Ryan R. White, Raymond J. Noonan, Farid Boulad, Francis P. Lach, Settara C. Chandrasekharappa, Peter J. Campbell, Roger D. Vaughan
Fanconi anemia (FA), a model syndrome of genome instability, is caused by a deficiency in DNA interstrand crosslink (ICL) repair resulting in chromosome breakage1–3. The FA repair pathway comprises at least 22 FANC proteins including BRCA1 and BRCA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9afd781051fca6c3cb7bdbe0af4e0c0
https://doi.org/10.1101/2021.08.14.456365
https://doi.org/10.1101/2021.08.14.456365
Autor:
Audrey Mauguen, Brian C. Shaffer, Ichelle van Roessel, Richard J. O'Reilly, Michael Scordo, Nancy A. Kernan, Christina Cho, Andrew L. Kung, Andromachi Scaradavou, Maria Cancio, Sergio Giralt, Miguel-Angel Perales, Barbara Spitzer, Kevin J. Curran, Madhavi Lakkaraja, Esperanza B. Papadopoulos, Elizabeth Klein, Sean M. Devlin, Farid Boulad, Susan E. Prockop, Ann A. Jakubowski, Gunjan L. Shah, Roni Tamari, Jaap Jan Boelens, Scott Avecilla, Josel D. Ruiz
Publikováno v:
Blood advances. 6(3)
Traditional weight-based dosing results in variable rabbit antithymocyte globulin (rATG) clearance that can delay CD4+ T-cell immune reconstitution (CD4+ IR) leading to higher mortality. In a retrospective pharmacokinetic/pharmacodynamic (PK/PD) anal