Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Maria Cabanillas"'
Autor:
Blessie Elizabeth Nelson, Jason Roszik, Jibran Ahmed, Carmelia Maria Noia Barretto, Mirella Nardo, Erick Campbell, Amber M Johnson, Sarina A. Piha-Paul, Isabella C. Glitza Oliva, Shiao-Pei Weathers, Maria Cabanillas, Milind Javle, Funda Meric-Bernstam, Vivek Subbiah
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Previous studies have shown the clinical benefit of rechallenging the RAF pathway in melanoma patients previously treated with BRAF inhibitors. 44 patients with multiple tumors harboring RAF alterations were rechallenged with a second RAF in
Externí odkaz:
https://doaj.org/article/536748e4fa9d4e778632dfc29b4e5ed7
Adaptive Darwinian off-target resistance mechanisms to selective RET inhibition in RET driven cancer
Autor:
Vivek Subbiah, Mohamed A. Gouda, J. Bryan Iorgulescu, Ramona Dadu, Keyur Patel, Steven Sherman, Maria Cabanillas, Mimi Hu, Luz E. Castellanos, Behrang Amini, Funda Meric-Bernstam, Tao Shen, Jie Wu
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract Patients treated with RET protein tyrosine kinase inhibitors (TKIs) selpercatinib or pralsetinib develop RET TKI resistance by secondary RET mutations or alterative oncogenes, of which alterative oncogenes pose a greater challenge for diseas
Externí odkaz:
https://doaj.org/article/2cb1c36a9a5542459cc53204816c9e28
Autor:
Blessie Elizabeth Nelson, Jason Roszik, Filip Janku, David S. Hong, Shumei Kato, Aung Naing, Sarina Piha-Paul, Siqing Fu, Apostolia Tsimberidou, Maria Cabanillas, Naifa Lamki Busaidy, Milind Javle, Lauren Averett Byers, John V. Heymach, Funda Meric-Bernstam, Vivek Subbiah
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-13 (2023)
Abstract Combined BRAF + MEK inhibition is FDA approved for BRAF V600E-mutant solid tumors except for colorectal cancer. However, beyond MAPK mediated resistance several other mechanisms of resistance such as activation of CRAF, ARAF, MET, P13K/AKT/m
Externí odkaz:
https://doaj.org/article/08c0964ed8d3474dbbdf8cf37ad472ba
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-5 (2020)
Abstract Background Thyroid malignancies are among the most common endocrine cancers worldwide. Owing to the angiogenic nature of these malignancies, tyrosine kinase inhibitors (TKIs) are an attractive potential treatment. However, TKIs have been ass
Externí odkaz:
https://doaj.org/article/c75733973394482fa535f2151a022b07
Autor:
Jessica Lee, Vivek Subbiah, Shuang Liu, Jason Roszik, David Hong, Funda Meric-Bernstam, John Heymach, Ramona Dadu, Kenneth Hess, Le Huang, Aparna Hegde, Alexander Y Andreev-Drakhlin, Maria Cabanillas, Mimi I Hu, Naifa L Busaidy, Steven I Sherman, Elizabeth G Grubbs, Siraj M Ali, Yasir Y Elamin, George R Simon, George R Blumenschein, Jr, Vassiliki A Papadimitrakopoulou
Publikováno v:
ESMO Open, Vol 5, Iss 5 (2020)
Purpose The receptor tyrosine kinase rearranged during transfection (RET) can be oncogenically activated by gene fusions or point mutations. Multikinase inhibitors such as cabozantinib, lenvatinib and vandetanib have demonstrated activity in RET-depe
Externí odkaz:
https://doaj.org/article/c90d0d405f934390885cdc8e42bce7c6
Publikováno v:
Journal of Clinical and Translational Endocrinology Case Reports, Vol 17, Iss , Pp 100066- (2020)
The present report describes the case of a 65-year-old white woman with a longstanding diagnosis of medullary thyroid cancer with metastatic disease and an extensive surgical history.She presented with late-onset folliculitis, hypertension, parkinson
Externí odkaz:
https://doaj.org/article/4679ba2915db4f4192c3f50f34df8a79
Autor:
Yu Han Chen, Maria Cabanillas, Jared Sperling, Li Xu, Maitrayee Goswami, Anastasios Maniakas, Michelle D. Williams, Stephen Y. Lai, Naifa Busaidy, Ramona Dadu, Mark E. Zafereo, Jennifer Rui Wang
Publikováno v:
Thyroid. 33:321-329
A prior history of thyroid and non-thyroid malignancies has traditionally been an exclusion criterion in patients with anaplastic thyroid carcinoma (ATC) seeking to enroll in clinical trials. In this study, we examined the impact of prior malignancie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b303c018336b8156bae6e4940f2d699c
https://doi.org/10.1089/thy.2022.0350
https://doi.org/10.1089/thy.2022.0350
Autor:
Jared A. Shenson, Mark E. Zafereo, Mark Lee, Kevin J. Contrera, Lei Feng, Mongkol Boonsripitayanon, Neil Gross, Ryan Goepfert, Anastasios Maniakas, Jennifer Rui Wang, Libby Grubbs, Ara Vaporciyan, Wayne Hofstetter, Stephen Swisher, Reza Mehran, David Rice, Boris Sepesi, Mara Antonoff, Maria Cabanillas, Naifa Busaidy, Ramona Dadu, Natalie L. Silver
Publikováno v:
HeadneckREFERENCES.
Advanced thyroid disease involving the mediastinum may be managed surgically with a combined transcervical and transthoracic approach. Contemporary analysis of this infrequently encountered cohort will aid the multidisciplinary team in personalizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561eb81477488bcd61c1df927d716b3f
https://pubmed.ncbi.nlm.nih.gov/36524701
https://pubmed.ncbi.nlm.nih.gov/36524701
Autor:
Blessie Elizabeth Nelson, Mohammed Gouda, Jason Roszik, Mimi L. Hu, Maria Cabanillas, Vivek Subbiah
Publikováno v:
Cancer Research. 83:4261-4261
Background: Understanding molecular biology of thyroid cancer has revolutionized diagnosis, tumor classifications and identifying effective precision oncology therapies. Methods: Using AACR GENIE database v.12, we cataloged genetic and co-occurring a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::069d1bb5173afa63cd809fc9a1483fc5
https://doi.org/10.1158/1538-7445.am2023-4261
https://doi.org/10.1158/1538-7445.am2023-4261
Autor:
Rim Ouni, Ying Henderson, Yunyun Chen, Naimah Turner, William Padron, Ali Dadbin, Elena McBeath Fujiwara, Jennifer R. Wang, Maria Cabanillas, Romana Dadu, Marie-Claude Hofmann, Mark E. Zafereo, Sang Taek Kim, Stephen Lai, Roza Nurieva
Publikováno v:
Leading Edge of Cancer Research Symposium: Poster Session.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::155b513aa2b81c9b71afa12c3ebe1a43
https://doi.org/10.52519/00072
https://doi.org/10.52519/00072