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Autor:
G. Robb Huhn, Celine Sparkes, Isabel Silva, Carla Reyes, Gisselle Perez, Fatema Khondker, Teriana Jones, Ashley Fragoso, Paula Contreras, Michelle Alvarez, Maria C. Zabala-Rodriguez, Suren A. Tatulian, Ken Teter
Publikováno v:
Biochemical and Biophysical Research Communications. 636:57-63
The cytolethal distending toxins (CDTs) produced by many Gram-negative pathogens are tripartite genotoxins with a single catalytic subunit (CdtB) and two cell-binding subunits (CdtA + CdtC). CDT moves by vesicle carriers from the cell surface to the