Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Maria C. Vogel"'
Publikováno v:
Journal of the American Chemical Society. 143:3086-3093
An interruption in Aβ homeostasis leads to the deposit of neurotoxic amyloid plaques and is associated with Alzheimer's disease. A supramolecular strategy based on the assembly of peptidomimetic agents into functional vesicles has been conceived for
Publikováno v:
Curr Opin Neurobiol
Macroautophagy (hereafter referred to as autophagy) is an essential quality-control pathway in neurons, which face unique functional and morphological challenges in maintaining the integrity of organelles and the proteome. To overcome these challenge
Autor:
Sandra Maday, Maria C. Vogel, Jessica Brandt Herr, Anip Anand, Christina Miranda, Vineet Vinay Kulkarni
Publikováno v:
The Journal of Cell Biology
Guimas Almeida previews new work from the Maday laboratory demonstrating the regulation of autophagosome dynamics and function within dendrites by synaptic activity.
Regulation of autophagy in neurons remains unclear. In this issue, Kulkarni et
Regulation of autophagy in neurons remains unclear. In this issue, Kulkarni et
Autor:
Keita Uchida, Izhak Kehat, Noa Erlitzki, Meghana Iyer, Benjamin L. Prosser, Sai Aung Phyo, Alexey Bogush, Emily A. Scarborough, Maria C. Vogel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Hypertension, exercise, and pregnancy are common triggers of cardiac remodeling, which occurs primarily through the hypertrophy of individual cardiomyocytes. During hypertrophy, stress-induced signal transduction increases cardiomyocyte transcription
Publikováno v:
Organic & Biomolecular Chemistry. 16:733-741
A library of N-substituted oligopyrrolamides was designed to modulate the aggregation kinetics of islet amyloid polypeptide (IAPP). IAPP is a hormonal peptide, co-secreted with insulin in the pancreatic β-cells. IAPP samples a variety of conformatio
Autor:
Marios S. Katsiotis, Ibrahim Chehade, Christy Maksoudian, Mazin Magzoub, Saeed M. Alhassan, Vineeth Mukundan, Maria C. Vogel
Publikováno v:
Archives of Biochemistry and Biophysics. 613:31-42
Prion diseases are associated with conversion of cellular prion protein (PrPC) into an abnormally folded and infectious scrapie isoform (PrPSc). We previously showed that peptides derived from the unprocessed N-termini of mouse and bovine prion prote
Publikováno v:
Biophysical Journal. 120:103a
Publikováno v:
Biophysical Journal. 116:479a-480a
Publikováno v:
The FASEB Journal
Overexpression of mitochondria-bound hexokinase II (HKII) in cancer cells plays an important role in their metabolic reprogramming and protects them against apoptosis, thereby facilitating their growth and proliferation. Here, we show that covalently
Publikováno v:
Biophysical Journal. 110:37a
Prion diseases are associated with the conversion of the benign cellular form of the prion protein (PrP(C)) into an abnormally folded and aggregated scrapie isoform (PrP(Sc)), which is also responsible for prion infectivity. We previously showed that