Výsledky vyhledávání - "Maria C. Trissal"

Akademický článek

VRK1 as a synthetic lethal target in VRK2 promoter–methylated cancers of the nervous system

Publikováno v: JCI Insight, Vol 7, Iss 19 (2022)

Collateral lethality occurs when loss of a gene/protein renders cancer cells dependent on its remaining paralog. Combining genome-scale CRISPR/Cas9 loss-of-function screens with RNA sequencing in over 900 cancer cell lines, we found that cancers of n

Externí odkaz: https://doaj.org/article/701d31e0fcdd484e84a5da699c9787f9

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BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Autor: Eshini Panditharatna, Joana G. Marques, Tingjian Wang, Maria C. Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves, Neekesh V. Dharia, Deyao Li, Samantha E. Hoffman, Guillaume Kugener, McKenzie L. Shaw, Hafsa M. Mire, Olivia A. Hack, Joshua M. Dempster, Caleb Lareau, Lingling Dai, Logan H. Sigua, Michael A. Quezada, Ann-Catherine J. Stanton, Meghan Wyatt, Zohra Kalani, Amy Goodale, Francisca Vazquez, Federica Piccioni, John G. Doench, David E. Root, Jamie N. Anastas, Kristen L. Jones, Amy Saur Conway, Sylwia Stopka, Michael S. Regan, Yu Liang, Hyuk-Soo Seo, Kijun Song, Puspalata Bashyal, William P. Jerome, Nathan D. Mathewson, Sirano Dhe-Paganon, Mario L. Suvà, Angel M. Carcaboso, Cinzia Lavarino, Jaume Mora, Quang-De Nguyen, Keith L. Ligon, Yang Shi, Sameer Agnihotri, Nathalie Y.R. Agar, Kimberly Stegmaier, Charles D. Stiles, Michelle Monje, Todd R. Golub, Jun Qi, Mariella G. Filbin

Publikováno v: Cancer Discovery. :OF1-OF26

Diffuse midline gliomas are uniformly fatal pediatric central nervous system cancers that are refractory to standard-of-care therapeutic modalities. The primary genetic drivers are a set of recurrent amino acid substitutions in genes encoding histone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53149d7866fec5060943e9c04bc735cf
https://doi.org/10.1158/2159-8290.cd-21-1491

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Supplementary Table from BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Autor: Mariella G. Filbin, Jun Qi, Todd R. Golub, Michelle Monje, Charles D. Stiles, Kimberly Stegmaier, Nathalie Y.R. Agar, Sameer Agnihotri, Yang Shi, Keith L. Ligon, Quang-De Nguyen, Jaume Mora, Cinzia Lavarino, Angel M. Carcaboso, Mario L. Suvà, Sirano Dhe-Paganon, Nathan D. Mathewson, William P. Jerome, Puspalata Bashyal, Kijun Song, Hyuk-Soo Seo, Yu Liang, Michael S. Regan, Sylwia Stopka, Amy Saur Conway, Kristen L. Jones, Jamie N. Anastas, David E. Root, John G. Doench, Federica Piccioni, Francisca Vazquez, Amy Goodale, Zohra Kalani, Meghan Wyatt, Ann-Catherine J. Stanton, Michael A. Quezada, Logan H. Sigua, Lingling Dai, Caleb Lareau, Joshua M. Dempster, Olivia A. Hack, Hafsa M. Mire, McKenzie L. Shaw, Guillaume Kugener, Samantha E. Hoffman, Deyao Li, Neekesh V. Dharia, Andrew Groves, Alexander Beck, Li Jiang, Ilon Liu, Maria C. Trissal, Tingjian Wang, Joana G. Marques, Eshini Panditharatna

Supplementary Table from BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d35750181befe4f5da4f650722948e9
https://doi.org/10.1158/2159-8290.22541856.v1

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Supplementary Figure from BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Supplementary Figure from BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f64519af0b30cd43dfae7d183877165
https://doi.org/10.1158/2159-8290.22541865

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Data from BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ee08482da42079229242adda130064
https://doi.org/10.1158/2159-8290.c.6549756

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Supplementary files from MIR142 Loss-of-Function Mutations Derepress ASH1L to Increase HOXA Gene Expression and Promote Leukemogenesis

Autor: Daniel C. Link, Pavan R. Reddy, Ivan Maillard, Timothy J. Ley, Todd A. Fehniger, Melissa M. Berrien-Elliott, Nishi Parikh, Gloria Jih, Yaping Sun, Jack Baty, Iris Kuo, Rahul Ramaswamy, Juo-Chin Yao, Terrence N. Wong, Maria C. Trissal

Supplementary Materials and Methods// Supplementary Figure 1. Supporting Figure 1. MIR142 mutations attenuate miR-142-3p and miR-142-5p functions.// Supplementary Figure 2. Supporting Figure 2. Mir142 loss alters differentiation in mature hematopoiet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0784f8483dcccce1ec02ecca51daef31
https://doi.org/10.1158/0008-5472.22419527.v1

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Data from MIR142 Loss-of-Function Mutations Derepress ASH1L to Increase HOXA Gene Expression and Promote Leukemogenesis

Point mutations in the seed sequence of miR-142-3p are present in a subset of acute myelogenous leukemia (AML) and in several subtypes of B-cell lymphoma. Here, we show that mutations associated with AML result both in loss of miR-142-3p function and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00d20bec30bf22003c8bc9e136e811dc
https://doi.org/10.1158/0008-5472.c.6510407.v1

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VRK1 is required in VRK2-methylated cancers of the nervous system

Autor: Jonathan So, Nathaniel W. Mabe, Bernhard Englinger, Sydney M. Moyer, Maria C. Trissal, Joana G. Marques, Jason Kwon, Brian Shim, Eshini Panditharatna, Daeun Jeong, David Mayhew, Justin Hwang, Kimberly Stegmaier, Mariella G. Filbin, William C. Hahn

Collateral lethality occurs when loss of one paralog renders cancer cells dependent on the remaining paralog. Combining genome scale CRISPR/Cas9 screens coupled with RNA-sequencing in over 900 cancer cell lines, we found that cancers of nervous syste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c09f1bdcdaac23f74cfe4e79563aa36
https://doi.org/10.1101/2021.12.28.474386

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Akademický článek

MicroRNA-223 regulates granulopoiesis but is not required for HSC maintenance in mice.

Autor: Maria C Trissal, Ricardo A DeMoya, Amy P Schmidt, Daniel C Link

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0119304 (2015)

MIR233 is genetically or epigenetically silenced in a subset of acute myeloid leukemia (AML). MIR223 is normally expressed throughout myeloid differentiation and highly expressed in hematopoietic stem cells (HSCs). However, the contribution of MIR223

Externí odkaz: https://doaj.org/article/b6f2776026db483b93c3aba60efec152

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