Perioperative Blood Transfusion Is Associated with Worse Survival in Patients Undergoing Radical Cystectomy after Neoadjuvant Chemotherapy for Muscle-Invasive Bladder Cancer

Autor: Tessa Ladner, Anna J. Black, Homayoun Zargar, Jonathan L. Wright, Andrew C. Thorpe, Todd M. Morgan, Jeff M. Holzbeierlein, Michael S. Cookson, Niels-Erik Jacobsen, Adrian S. Fairey, Colin P. N. Dinney, Maria C. Mir, Laura-Maria Krabbe, Jeffrey S. Montgomery, Nikhil Vasdev, Evan Y. Yu, Evanguelos Xylinas, Andrew J. Stephenson, Jay B. Shah, Siamak Daneshmand, Kamran Zargar-Shoshtari, Philippe E. Spiess, Laura S. Mertens, Bas W. G. van Rhijn, Petros Grivas, Wassim Kassouf, Marc A. Dall’Era, Srikala S. Sridhar, Jonathan S. McGrath, Jonathan Aning, Shahrokh F. Shariat, Trinity J. Bivalacqua, Scott A. North, Daniel A. Barocas, Yair Lotan, Peter C. Black

Publikováno v: Société Internationale d’Urologie Journal, Vol 5, Iss 3, Pp 202-213 (2024)

Objectives: Perioperative blood transfusion (PBT) has been associated with worse survival after radical cystectomy (RC) in patients with muscle-invasive bladder cancer (MIBC). Here, we evaluated the association between PBT and survival after RC that

Externí odkaz: https://doaj.org/article/014c07b617934d568005c539c0294ffb

Proposal for a Two-Tier Re-classification of Stage IV/M1 domain of Renal Cell Carcinoma into M1 ('Oligometastatic') and M2 ('Polymetastatic') subdomains: Analysis of the Registry for Metastatic Renal Cell Carcinoma (REMARCC)

Autor: Margaret F. Meagher, Maria C. Mir, Andrea Minervini, Maximilian Kriegmair, Matthias Heck, Francesco Porpiglia, Siska Van Bruwaene, Estefania Linares, Vital Hevia, Maurizio D’Anna, Alessandro Veccia, Eduard Roussel, Francesco Claps, Carlotta Palumbo, Michele Marchioni, Jonathan Afari, Cesare Saitta, Franklin Liu, Jose Rubio, Riccardo Campi, Andrea Mari, Thomas Amiel, Enrico Checcucci, Mireia Musquera, Georgi Guruli, Nicola Pavan, Maarten Albersen, Alessandro Antonelli, Tobias Klatte, Riccardo Autorino, Rana R. McKay, Ithaar H. Derweesh

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

PurposeWe hypothesized that two-tier re-classification of the “M” (metastasis) domain of the Tumor-Node-Metastasis (TNM) staging of Renal Cell Carcinoma (RCC) may improve staging accuracy than the current monolithic classification, as advancement

Externí odkaz: https://doaj.org/article/16ddf590e7314085a53f58a66816dc64

Multicenter evaluation of neoadjuvant and induction gemcitabine–carboplatin versus gemcitabine–cisplatin followed by radical cystectomy for muscle-invasive bladder cancer

Autor: Sarah M. H. Einerhand, Anna J. Black, Homayoun Zargar, Adrian S. Fairey, Colin P. Dinney, Maria C. Mir, Laura-Maria Krabbe, Michael S. Cookson, Niels-Erik Jacobson, Jeffrey S. Montgomery, Nikhil Vasdev, Evan Y. Yu, Evanguelos Xylinas, Wassim Kassouf, Marc A. Dall’Era, Srikala S. Sridhar, Jonathan S. McGrath, Jonathan Aning, Shahrokh F. Shariat, Jonathan L. Wright, Andrew C. Thorpe, Todd M. Morgan, Jeff M. Holzbeierlein, Trinity J. Bivalacqua, Scott North, Daniel A. Barocas, Yair Lotan, Petros Grivas, Jorge A. Garcia, Andrew J. Stephenson, Jay B. Shah, Siamak Daneshmand, Kamran Zargar-Shoshtari, Philippe E. Spiess, Bas W. G. van Rhijn, Peter C. Black, Laura S. Mertens

Publikováno v: Einerhand, S M H, Black, A J, Zargar, H, Fairey, A S, Dinney, C P, Mir, M C, Krabbe, L-M, Cookson, M S, Jacobson, N-E, Montgomery, J S, Vasdev, N, Yu, E Y, Xylinas, E, Kassouf, W, Dall’Era, M A, Sridhar, S S, McGrath, J S, Aning, J, Shariat, S F, Wright, J L, Thorpe, A C, Morgan, T M, Holzbeierlein, J M, Bivalacqua, T J, North, S, Barocas, D A, Lotan, Y, Grivas, P, Garcia, J A, Stephenson, A J, Shah, J B, Daneshmand, S, Zargar-Shoshtari, K, Spiess, P E, van Rhijn, B W G, Black, P C & Mertens, L S 2022, ' Multicenter evaluation of neoadjuvant and induction gemcitabine–carboplatin versus gemcitabine–cisplatin followed by radical cystectomy for muscle-invasive bladder cancer ', World Journal of Urology, vol. 40, no. 11, pp. 2707-2715 . https://doi.org/10.1007/s00345-022-04160-7
World Journal of Urology, 40(11), 2707-2715. Springer Verlag

Purpose: Cisplatin-based chemotherapy followed by radical cystectomy (RC) is recommended in patients with muscle-invasive bladder cancer (MIBC). However, up to 50% of patients are cisplatin ineligible. The aim of this study was to compare clinical ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af45b70fb303ee01ef4da2180af17253
http://www.scopus.com/inward/record.url?scp=85139142556&partnerID=8YFLogxK

Adverse Events of Immune Checkpoint Inhibitors Therapy for Urologic Cancer Patients in Clinical Trials: A Collaborative Systematic Review and Meta-analysis

Autor: Zhenjie Wu, Qi Chen, Le Qu, Mingmin Li, Linhui Wang, Maria C. Mir, Umberto Carbonara, Savio D. Pandolfo, Peter C. Black, Asit K Paul, Giuseppe Di Lorenzo, Francesco Porpiglia, Andrea Mari, Andrea Necchi, Morgan Rouprêt, Sarah P. Psutka, Riccardo Autorino

Publikováno v: European Urology. 81:414-425

Therapies based on immune checkpoint inhibitors (ICIs) are transforming the treatment landscape of urologic oncology. Nevertheless, an exhaustive overview of the toxicity spectrum of these novel therapies has yet to be provided.To comprehensively inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf31e849b30886a13dbe2e781d01063a
https://doi.org/10.1016/j.eururo.2022.01.028

Data from The Investigational Aurora Kinase A Inhibitor MLN8237 Induces Defects in Cell Viability and Cell-Cycle Progression in Malignant Bladder Cancer Cells In Vitro and In Vivo

Autor: Donna E. Hansel, Alexandru Almasan, Bin T. Teh, Zhongfa Zhang, Jeffrey A. Ecsedy, Robert Dreicer, Daniel Lindner, Yvonne Parker, Maria C. Mir, Kamini Singh, Ning Zhou

Purpose: Despite more than 70,000 new cases of bladder cancer in the United States annually, patients with advanced disease have a poor prognosis due to limited treatment modalities. We evaluated Aurora kinase A, identified as an upregulated candidat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af495852bbd5460d77991d5405dd919c
https://doi.org/10.1158/1078-0432.c.6522923