Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Maria C. Goggin"'
Autor:
Robert C. Glen, Karen Reynolds, David L. Selwood, Mark A. Tatlock, David G. Brummell, Maria C. Goggin, Grant Wishart
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:1089-1092
A lipophilicity constrained library of 5-carboxamido 1-benzyl-3-(3-dimethylaminopropyloxy)-1H-pyrazoles was prepared by solution-phase parallel synthesis with removal of acidic by-products using the strongly basic MP-carbonate resin. Compounds show b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ced756e6e0794fa874100c8511c300c
https://doi.org/10.1016/s0960-894x(01)00141-x
https://doi.org/10.1016/s0960-894x(01)00141-x
Autor:
Grant Wishart, Robert C. Glen, David G. Brummell, Maria C. Goggin, Karen Reynolds, Mark A. Tatlock, David L. Selwood
Publikováno v:
ChemInform. 32
A lipophilicity constrained library of 5-carboxamido 1-benzyl-3-(3-dimethylaminopropyloxy)-1H-pyrazoles was prepared by solution-phase parallel synthesis with removal of acidic by-products using the strongly basic MP-carbonate resin. Compounds show b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a75fb64cbf0171a22b633244e7d3c2
https://doi.org/10.1002/chin.200133130
https://doi.org/10.1002/chin.200133130
Autor:
David L. Selwood, David Madge, David G. Brummell, Ian G. Charles, Sylvie Meillerais, Robert C. Glen, Marcel Kling, Mark A. Tatlock, Qian Liu, Karen Reynolds, Grant Wishart, Joanna Budworth, Kenneth L. Powell, Jeremy N. Stables, Patricia A. Fernandez, Maria C. Goggin, Richard O. Campbell, Guillaume E. Burtin, Chi-Kit Woo, Kerry A. Wheeler, Graham D. Spacey, Surinder S. Chana, Adrian J. Hobbs
Publikováno v:
Journal of medicinal chemistry. 44(1)
Database searching and compound screening identified 1-benzyl-3-(3-dimethylaminopropyloxy)-indazole (benzydamine, 3) as a potent activator of the nitric oxide receptor, soluble guanylate cyclase. A comprehensive structure-activity relationship study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf9a2fbf7680e57afd4057e7b9a213a
https://pubmed.ncbi.nlm.nih.gov/11141091
https://pubmed.ncbi.nlm.nih.gov/11141091