Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Maria C. Denis"'
Autor:
Yunhan Zhao, Bettina Celvin, Maria C. Denis, Niki Karagianni, Cecilia Aulin, Farasat Zaman, Lars Sävendahl
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Children with chronic inflammation are often treated with glucocorticoids (GCs) and many of them experience growth retardation. It is poorly understood how GCs interact with inflammatory cytokines causing growth failure as earlier experiment
Externí odkaz:
https://doaj.org/article/2402ec5452e543b08d1b549842f78486
Autor:
Dimitra Papadopoulou, Fani Roumelioti, Christos Tzaferis, Panagiotis Chouvardas, Anna-Kathrine Pedersen, Filippos Charalampous, Eleni Christodoulou-Vafeiadou, Lydia Ntari, Niki Karagianni, Maria C. Denis, Jesper V. Olsen, Alexios N. Matralis, George Kollias
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Synovial fibroblasts (SFs) are key pathogenic drivers in rheumatoid arthritis (RA). Their in vivo activation by TNF is sufficient to orchestrate full arthritic pathogenesis in animal models, and TNF blockade proved efficacious for a high percentage o
Externí odkaz:
https://doaj.org/article/1d4158356be44267b7a2df77d6bc97a8
Autor:
Anthi Kolokotroni, Evi Gkikopoulou, Vagelis Rinotas, Lydia Ntari, Danae Zareifi, Maritina Rouchota, Sophia Sarpaki, Ilias Lymperopoulos, Leonidas G. Alexopoulos, George Loudos, Maria C. Denis, Niki Karagianni, Eleni Douni
Publikováno v:
Cancers, Vol 15, Iss 15, p 4006 (2023)
Receptor activator of nuclear factor-κB ligand (RANKL) is critically involved in mammary gland pathophysiology, while its pharmaceutical inhibition is being currently investigated in breast cancer. Herein, we investigated whether the overexpression
Externí odkaz:
https://doaj.org/article/d414bf25a8fd4804b9ebfadad1912f99
Autor:
Irini Papazian, Eleni Tsoukala, Athena Boutou, Maria Karamita, Konstantinos Kambas, Lida Iliopoulou, Roman Fischer, Roland E. Kontermann, Maria C. Denis, George Kollias, Hans Lassmann, Lesley Probert
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-21 (2021)
Abstract Background During inflammatory demyelination, TNF receptor 1 (TNFR1) mediates detrimental proinflammatory effects of soluble TNF (solTNF), whereas TNFR2 mediates beneficial effects of transmembrane TNF (tmTNF) through oligodendroglia, microg
Externí odkaz:
https://doaj.org/article/f835375dd4814f7eb875ab3d9fd3f00f
Autor:
Lydia Ntari, Christoforos Nikolaou, Ksanthi Kranidioti, Dimitra Papadopoulou, Eleni Christodoulou-Vafeiadou, Panagiotis Chouvardas, Florian Meier, Christina Geka, Maria C. Denis, Niki Karagianni, George Kollias
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background New medications for Rheumatoid Arthritis (RA) have emerged in the last decades, including Disease Modifying Antirheumatic Drugs (DMARDs) and biologics. However, there is no known cure, since a significant proportion of patients re
Externí odkaz:
https://doaj.org/article/6a3d53e66c924ce194559ad42cdbb41b
Autor:
Eleni Christodoulou-Vafeiadou, Christina Geka, Lydia Ntari, Ksanthi Kranidioti, Eleni Argyropoulou, Florian Meier, Marietta Armaka, Iordanis Mourouzis, Constantinos Pantos, Maritina Rouchota, George Loudos, Maria C. Denis, Niki Karagianni, George Kollias
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background The transmembrane-TNF transgenic mouse, TgA86, has been shown to develop spontaneously peripheral arthritis with signs of axial involvement. To assess similarity to human spondyloarthritis, we performed detailed characterization o
Externí odkaz:
https://doaj.org/article/0b4b1e377f6c41f59e25d3ba4529fedd
Autor:
Fani Roumelioti, Christos Tzaferis, Dimitris Konstantopoulos, Dimitra Papadopoulou, Alejandro Prados, Maria Sakkou, Anastasios Liakos, Panagiotis Chouvardas, Theodore Meletakos, Yiannis Pandis, Niki Karagianni, Maria C Denis, Maria Fousteri, Maria Armaka, George Kollias
Publikováno v:
eLife, Vol 13 (2024)
miRNAs constitute fine-tuners of gene expression and are implicated in a variety of diseases spanning from inflammation to cancer. miRNA expression is deregulated in rheumatoid arthritis (RA); however, their specific role in key arthritogenic cells s
Externí odkaz:
https://doaj.org/article/e5d50d4d00c3408c8809b26c70ef81cd
Autor:
Roman Fischer, Maria Karamita, Roland E. Kontermann, Hans Lassmann, Maria C Denis, Konstantinos Kambas, Eleni Tsoukala, Irini Papazian, Lida Iliopoulou, Lesley Probert, George Kollias, Athena Boutou
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-21 (2021)
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-21 (2021)
Background During inflammatory demyelination, TNF receptor 1 (TNFR1) mediates detrimental proinflammatory effects of soluble TNF (solTNF), whereas TNFR2 mediates beneficial effects of transmembrane TNF (tmTNF) through oligodendroglia, microglia, and
Autor:
Marije I. Koenders, Christina Geka, Nina Woodworth, Marietta Armaka, Birgit Niederreiter, Stephan Blüml, Margriet J. Vervoordeldonk, Anita Fischer, Maria C Denis, Johan Bäcklund, George Kollias, Rikard Holmdahl, Markus H. Hoffmann, Florence Apparailly, Kutty Selva Nandakumar, Silvia Hayer
Publikováno v:
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2021, pp.annrheumdis-2020-219247. ⟨10.1136/annrheumdis-2020-219247⟩
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2021, pp.annrheumdis-2020-219247. ⟨10.1136/annrheumdis-2020-219247⟩
Animal models for inflammatory arthritides such as rheumatoid arthritis (RA) and psoriatic arthritis are widely accepted and frequently used to identify pathological mechanisms and validate novel therapeutic strategies. Unfortunately, many publicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a9c754b9c866762104a9e4bfaa52d1
https://hal.umontpellier.fr/hal-03157626
https://hal.umontpellier.fr/hal-03157626
Autor:
Panagiotis Chouvardas, Lydia Ntari, Florian Meier, Niki Karagianni, Christoforos Nikolaou, Maria C Denis, Ksanthi Kranidioti, Dimitra Papadopoulou, Eleni Christodoulou-Vafeiadou, George Kollias, Christina Geka
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Journal of Translational Medicine
Ntari, Lydia; Nikolaou, Christoforos; Kranidioti, Ksanthi; Papadopoulou, Dimitra; Christodoulou-Vafeiadou, Eleni; Chouvardas, Panagiotis; Meier, Florian; Geka, Christina; Denis, Maria C; Karagianni, Niki; Kollias, George (2021). Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment. Journal of translational medicine, 19(1), p. 165. BioMed Central 10.1186/s12967-021-02764-y
Journal of Translational Medicine
Ntari, Lydia; Nikolaou, Christoforos; Kranidioti, Ksanthi; Papadopoulou, Dimitra; Christodoulou-Vafeiadou, Eleni; Chouvardas, Panagiotis; Meier, Florian; Geka, Christina; Denis, Maria C; Karagianni, Niki; Kollias, George (2021). Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment. Journal of translational medicine, 19(1), p. 165. BioMed Central 10.1186/s12967-021-02764-y
Background New medications for Rheumatoid Arthritis (RA) have emerged in the last decades, including Disease Modifying Antirheumatic Drugs (DMARDs) and biologics. However, there is no known cure, since a significant proportion of patients remain or b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1b1cfee6f7d565dac510e282e3568a
https://publica.fraunhofer.de/handle/publica/269058
https://publica.fraunhofer.de/handle/publica/269058