IgM levels in plasma predict outcome in severe pandemic influenza

Autor: Cristóbal León, Jordi Vallés, Ana Loza, Antoni Torres, Silvia Rojo, Victoria Fernández, Cristina López-Mestanza, Raúl Ortiz de Lejarazu, Leonor Nogales, Ignacio Martin-Loeches, Jesús Blanco, Catia Cilloniz, Lorenzo Socias, Angel Estella, Maria C Gallegos, Jesus F. Bermejo-Martin, Mar Justel, Sara Rosich, Raquel Almansa, Monica Gordon, Jose Ángel Berezo, David Andaluz-Ojeda, Paula Ramirez

Publikováno v: JOURNAL OF CLINICAL VIROLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Little is known on the participation of immunoglobulin isotypes and subclasses in the pathogenesis of the severe disease caused by the pandemic influenza virus (influenza A(H1N1)pdm09).(1) To evaluate the association between plasma levels of IgG1, Ig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbdbf2f1a02fda61f325dba6da91594
https://pubmed.ncbi.nlm.nih.gov/24076102

Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza

Autor: Tomás Pumarola, Jesús Blanco, Salvador Resino, Raquel Almansa, Carmen Barroso Castro, Felipe Bobillo, Jesus F. Bermejo-Martin, Paula Mateo, Raúl Ortiz de Lejarazu, David Banner, Luoling Xu, Milagros González-Rivera, Cristóbal León, Maria C Gallegos, Andrés Antón, Enrique Maravi, Longsi Ran, Maria Angeles Marcos, Fernando Martin-Sanchez, Paula Ramirez, Pedro Merino, Ignacio Martin-Loeches, David Andaluz, David J. Kelvin, Lorenzo Socias, Guillermo Lopez-Campos, Ana Loza, Monica Gordon, Francisco Gandía, Victoria Fernández, Jose Mª Eiros, Jordi Rello

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
BMC Infectious Diseases, Vol 11, Iss 1, p 232 (2011)
BMC Infectious Diseases
BMC INFECTIOUS DISEASES
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Background: Severe disease caused by 2009 pandemic influenza A/H1N1virus is characterized by the presence of hypercytokinemia. The origin of the exacerbated cytokine response is unclear. As observed previously, uncontrolled influenza virus replicatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63abee4bea8df9c879d2f4e5bb471b93
http://hdl.handle.net/20.500.12105/6826

Host adaptive immunity deficiency in severe pandemic influenza

Autor: Ana Loza, Felipe Bobillo, Salvador Resino, Enrique Maravi, Pedro Merino, Luoling Xu, Fernando Martin-Sanchez, Jesus F. Bermejo-Martin, Raquel Almansa, Monica Gordon, Cristóbal León, Jordi Rello, David Andaluz, Raúl Ortiz de Lejarazu, Sara Aldunate, Silvia Rojo, Tomás Pumarola, David Banner, Maria Angeles Marcos, Jesús Blanco, Lucia Rico, Longsi Ran, Derek C. K. Ng, Francisco Gandía, Maria C Gallegos, Maria J Gómez-Sánchez, Victoria Fernández, Verónica Iglesias, Lorenzo Socias, David J. Kelvin, Paula Ramirez, David Varillas, Carmen Barroso Castro, Guillermo Lopez-Campos, Ignacio Martin-Loeches, Andrés Antón, Begoña Nogueira

Publikováno v: Critical Care
Repisalud
Instituto de Salud Carlos III (ISCIII)
CRITICAL CARE
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Introduction: Pandemic A/H1N1/2009 influenza causes severe lower respiratory complications in rare cases. The association between host immune responses and clinical outcome in severe cases is unknown. Methods: We utilized gene expression, cytokine pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5ed66022d34150dcfc2e2c955020f7
https://doi.org/10.1186/cc9259