Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maria C Cuitino"'
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 3, p e1009949 (2022)
Automatic characterization of fluorescent labeling in intact mammalian tissues remains a challenge due to the lack of quantifying techniques capable of segregating densely packed nuclei and intricate tissue patterns. Here, we describe a powerful deep
Externí odkaz:
https://doaj.org/article/5044be5b25b447c88f08881c256a3156
Autor:
Julia E Lefler, Catherine B MarElia-Bennett, Katie A Thies, Blake E Hildreth, Sudarshana M Sharma, Jason R Pitarresi, Lu Han, Caroline Everett, Christopher Koivisto, Maria C Cuitino, Cynthia D Timmers, Elizabeth O’Quinn, Melodie Parrish, Martin J Romeo, Amanda J Linke, G Aaron Hobbs, Gustavo Leone, Denis C Guttridge, Teresa A Zimmers, Gregory B Lesinski, Michael C Ostrowski
Publikováno v:
Life Science Alliance. 5:e202201460
Pancreatic ductal adenocarcinoma (PDAC) is associated with an incredibly dense stroma, which contributes to its recalcitrance to therapy. Cancer-associated fibroblasts (CAFs) are one of the most abundant cell types within the PDAC stroma and have con
Autor:
Jinghai Wu, Xin Liu, Sunayana G Nayak, Jason R Pitarresi, Maria C Cuitiño, Lianbo Yu, Blake E Hildreth, Katie A Thies, Daniel J Schilling, Soledad A Fernandez, Gustavo Leone, Michael C Ostrowski
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184984 (2017)
The contribution of the tumor microenvironment to the development of pancreatic adenocarcinoma (PDAC) is unclear. The LSL-KrasG12D/+;LSL-p53R172H/+;Pdx-1-Cre (KPC) tumor model, which is widely utilized to faithfully recapitulate human pancreatic canc
Externí odkaz:
https://doaj.org/article/5070e05f06694d96863c592eb17d18ef
Autor:
Julie A Wallace, Jason R Pitarresi, Nandini eSharma, Marilly ePalettas, Maria C Cuitiño, Steven T Sizemore, Lianbo eYu, Allen eSanderlin, Thomas J Rosol, Kamal D. Mehta, Gina M Sizemore, Michael C Ostrowski
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
Protein kinase C beta (PKCβ) expression in breast cancer is associated with a more aggressive tumor phenotype, yet the mechanism for how PKCβ is pro-tumorigenic in this disease is still unclear. Interestingly, while it is known that PKCβ mediates
Externí odkaz:
https://doaj.org/article/e3eef365cb8b48ebb3ff8b781d665691