Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Maria Björkqvist"'
Autor:
Maria Björkqvist
Publikováno v:
EBioMedicine, Vol 98, Iss , Pp 104882- (2023)
Externí odkaz:
https://doaj.org/article/d02f7c0ed776482fb0f09771b60aa5a3
Autor:
Oleg Zhukov, Chen He, Rana Soylu-Kucharz, Changsi Cai, Andreas D. Lauritzen, Blanca Irene Aldana, Maria Björkqvist, Martin Lauritzen, Krzysztof Kucharz
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionDysfunction of the cerebral vasculature is considered one of the key components of Alzheimer’s disease (AD), but the mechanisms affecting individual brain vessels are poorly understood.MethodsHere, using in vivo two-photon microscopy in
Externí odkaz:
https://doaj.org/article/b3fa1bc5def64695840bbc4a5b1b8b6e
Autor:
Elna Dickson, Amoolya Sai Dwijesha, Natalie Andersson, Sofia Lundh, Maria Björkqvist, Åsa Petersén, Rana Soylu-Kucharz
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Structural changes and neuropathology in the hypothalamus have been suggested to contribute to the non-motor manifestations of Huntington’s disease (HD), a neurodegenerative disorder caused by an expanded cytosine-adenine-guanine (CAG) repeat in th
Externí odkaz:
https://doaj.org/article/ced1aed2ba324772b881459b9328d9b9
Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice
Publikováno v:
Molecular Metabolism, Vol 57, Iss , Pp 101439- (2022)
Objective: In Huntington's disease (HD), the disease-causing huntingtin (HTT) protein is ubiquitously expressed and causes both central and peripheral pathology. In clinical HD, a higher body mass index has been associated with slower disease progres
Externí odkaz:
https://doaj.org/article/2d6cb01f08ed4c56a23cb1bbcdbf28a4
Publikováno v:
Heliyon, Vol 7, Iss 8, Pp e07808- (2021)
Huntington disease (HD) is a fatal neurodegenerative movement disorder caused by an expanded CAG repeat in the huntingtin gene (HTT). The mutant huntingtin protein is ubiquitously expressed, but only certain brain regions are affected. The hypothalam
Externí odkaz:
https://doaj.org/article/1e0540530f364a9a96169f5ff80a3e96
Autor:
Marie Sjögren, Rana Soylu-Kucharz, Unali Dandunna, Tiberiu Loredan Stan, Michele Cavalera, Åsa Sandelius, Henrik Zetterberg, Maria Björkqvist
Publikováno v:
Neurobiology of Disease, Vol 132, Iss , Pp - (2019)
Body weight has been shown to be a predictor of clinical progression in Huntington's disease (HD). Alongside widespread neuronal pathology, both HD patients and the R6/2 mouse model of HD exhibit weight loss and increased energy expenditure, providin
Externí odkaz:
https://doaj.org/article/abfecb89895d41dd9c7b6dcfa84692de
Autor:
Ulrike Träger, Ralph Andre, Anna Magnusson-Lind, James R.C. Miller, Colúm Connolly, Andreas Weiss, Stephan Grueninger, Edina Silajdžić, Donna L. Smith, Blair R. Leavitt, Gillian P. Bates, Maria Björkqvist, Sarah J. Tabrizi
Publikováno v:
Neurobiology of Disease, Vol 73, Iss , Pp 388-398 (2015)
Inflammation is a growing area of research in neurodegeneration. In Huntington's disease (HD), a fatal inherited neurodegenerative disease caused by a CAG-repeat expansion in the gene encoding huntingtin, patients have increased plasma levels of infl
Externí odkaz:
https://doaj.org/article/2bb72a14457c461b9f15b194b9926f85
Autor:
Melinda Rezeli, Ákos Végvári, Edina Silajdžić, Maria Björkqvist, Sarah J. Tabrizi, Thomas Laurell, György Marko-Varga
Publikováno v:
EuPA Open Proteomics, Vol 3, Iss C, Pp 68-75 (2014)
The development of an MRM assay for the measurements of six inflammatory markers is presented. We report a robust and sensitive quantitative assay with a relative standard deviation of
Externí odkaz:
https://doaj.org/article/2a6da7c523054d958ea457b57822000c
Autor:
Rajasree Nambron, Edina Silajdžić, Eirini Kalliolia, Chris Ottolenghi, Peter Hindmarsh, Nathan R Hill, Seán J Costelloe, Nicholas G Martin, Vincenzo Positano, Hilary C Watt, Chris Frost, Maria Björkqvist, Thomas T Warner
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146480 (2016)
BackgroundHuntington's disease patients have a number of peripheral manifestations suggestive of metabolic and endocrine abnormalities. We, therefore, investigated a number of metabolic factors in a 24-hour study of Huntington's disease gene carriers
Externí odkaz:
https://doaj.org/article/418822ab2bc146d98df51b9f0cc3fa02
Autor:
Andrew C McCourt, Lovisa Jakobsson, Sara Larsson, Cecilia Holm, Sarah Piel, Eskil Elmér, Maria Björkqvist
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159870 (2016)
Huntington's disease (HD) is a fatal, autosomal dominantly inherited neurodegenerative disorder, characterised not only by progressive cognitive, motor and psychiatric impairments, but also of peripheral pathology. In both human HD and in mouse model
Externí odkaz:
https://doaj.org/article/71757093ac3f47a7a2b0461599cfce01