Výsledky vyhledávání - "Maria Bintanel-Morcillo"

Akademický článek

Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)

The molecular identity of renal glomerular cells is poorly characterized and rodent glomerulopathy models translate poorly to humans. Here, the authors show molecular signatures of glomerulus-associated cells using single cell RNA sequencing and high

Externí odkaz: https://doaj.org/article/fe04160ada134a20a0af7aef65e1f106

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Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes

Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)

Molecular characterization of the individual cell types in human kidney as well as model organisms are critical in defining organ function and understanding translational aspects of biomedical research. Previous studies have uncovered gene expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3a4f29f09880dc96b34a15c5c64cda
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-455805

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Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms

Autor: Cristina I. Caescu, Francesco Ramirez, Roshan Borkar, Jay D. Humphrey, Guillaume Jondeau, Bart Spronck, Pauline Arnaud, Evren U. Azeloglu, Jens Hansen, Alan D. Weinberg, Maria Bintanel-Morcillo, Sae-Il Murtada, Ravi Iyengar, Catherine Boileau, James M. Gallo, Rhodora Cristina Calizo, Josephine Galatioto

Publikováno v: JCI INSIGHT, 4(11):027652. American Society for Clinical Investigation

Marfan syndrome (MFS) is associated with mutations in fibrillin-1 that predispose afflicted individuals to progressive thoracic aortic aneurysm (TAA) leading to dissection and rupture of the vessel wall. Here we combined computational and experimenta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc854adf7edabc91dc15990a05ecbe9
https://cris.maastrichtuniversity.nl/en/publications/5bb48844-d5dc-4bc6-9fe9-a20fe1efecac

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Abstract 307: Circulating sRAGE is Associated With Aortic Dysfunction in Mice Models of Thoracic Aortic Aneurysm

Autor: Josephine Galatioto, Eric Lai, Maria Bintanel-Morcillo, Tao Wang, Giovanni Ferrari, Reed E Pyeritz, Joseph E Bavaria, Emanuela Branchetti

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 37

Backgound: The Receptor for Advanced Glycation End products (RAGE) and its ligands are associated with vascular remodeling and trigger the release of a soluble receptor (sRAGE). We demonstrated that sRAGE is elevated in patients with thoracic aortic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f0d12ad774313a910a314d477b447fd
https://doi.org/10.1161/atvb.37.suppl_1.307

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Improved rat steatotic and nonsteatotic liver preservation by the addition of epidermal growth factor and insulin-like growth factor-I to University of Wisconsin solution

Autor: Anna Serafín, Maria Bintanel-Morcillo, Marta Massip-Salcedo, Olivier Boillot, Ismail Ben Mosbah, Antoni Rimola, Juan Rodés, Araní Casillas-Ramírez, Joan Roselló-Catafau, Susagna Padrissa-Altés, Carmen A. Peralta, I. Alfany-Fernandez, M. Amine Zaouali

Publikováno v: Liver Transplantation. 16:1098-1111

This study examined the effects of epidermal growth factor (EGF) and insulin-like growth factor-I (IGF-I) supplementation to University of Wisconsin solution (UW) in steatotic and nonsteatotic livers during cold storage. Hepatic injury and function w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08d93c57dcbf18b6caf2ee555844c880
https://doi.org/10.1002/lt.22126

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Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia-reperfusion

Autor: Mohamed Amine Zaouali, Maria Bintanel-Morcillo, Joan Rodés, I. Ben Mosbah, Joan Roselló-Catafau, C Martel, I. Alfany-Fernandez, Antonio Rimola, Catherine Brenner, Carmen A. Peralta

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Death & Disease

During partial hepatectomy, ischemia-reperfusion (I/R) is commonly applied in clinical practice to reduce blood flow. Steatotic livers show impaired regenerative response and reduced tolerance to hepatic injury. We examined the effects of tauroursode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ad263a6aa6843651c12c591eaec975
http://hdl.handle.net/10261/76115

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Therapeutic targets in liver transplantation: angiotensin II in nonsteatotic grafts and angiotensin-(1-7) in steatotic grafts

Autor: A. Casillas-Ramirez, Carmen A. Peralta, Maria Bintanel-Morcillo, Carlos M. Ferrario, Anna Serafín, K B Brosnihan, Antonio Rimola, Joan Rodés, Joan Roselló-Catafau, I. Alfany-Fernandez

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Numerous steatotic livers are discarded as unsuitable for transplantation because of their poor tolerance of ischemia-reperfusion(I/R). The injurious effects of angiotensin (Ang)-II and the benefits of Ang-(1-7) in various pathologies are well docume

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808ef29168e8f939d3a465d6f45bf8c1
https://pubmed.ncbi.nlm.nih.gov/19191767

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Insulin-like growth factor and epidermal growth factor treatment: new approaches to protecting steatotic livers against ischemia-reperfusion injury

Autor: Maria Bintanel-Morcillo, Anna Pertosa, Araní Casillas-Ramírez, Ismail Ben Mosbah, Antoni Rimola, Joan Roselló-Catafau, Carmen A. Peralta, Carme Xaus, Juan Rodés, Susagna Padrissa-Altés, I. Alfany-Fernandez, Amine Zaouali

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Hepatic steatosis is a major risk factor in ischemia-reperfusion (I/R). IGF-binding proteins (IGFBPs) modulate IGF-I action by transporting circulating IGF-I to its sites of action. Epidermal growth factor (EGF) stimulates IGF-I synthesis in vitro. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b1494c18edb2b8ab2cdba6b3f008a2
http://hdl.handle.net/10261/31633

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Inhibition of angiotensin II action protects rat steatotic livers against ischemia-reperfusion injury

Autor: Maria Bintanel-Morcillo, Fernando Silva Ramalho, Antoni Rimola, Juan Rodés, Mohammed Amine-Zaouali, Marta Massip-Salcedo, Vicente Arroyo, Araní Casillas-Ramírez, Anna Serafín, Joan Roselló-Catafau, Carmen A. Peralta, Susagna Padrissa-Altés

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

[Objective]: We examined whether pharmacologic strategies blocking angiotensin II actions protect steatotic livers against ischemia-reperfusion (I/R) injury. The effects of ischemic preconditioning (PC) on angiotensin II were also evaluated.
[De

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb15d91e1f3d88d560198e4f9d057c1
http://hdl.handle.net/10261/37348

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