Purity and DNA content of AAV capsids assessed by analytical ultracentrifugation and orthogonal biophysical techniques

Autor: Klaus Richter, Christine Wurm, Kim Strasser, Jana Bauer, Maria Bakou, Ross VerHeul, Shawn Sternisha, Andrea Hawe, Michael Salomon, Tim Menzen, Akash Bhattacharya

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc543c2210f12b4aa3004a42aa53954c
https://doi.org/10.1016/j.ejpb.2023.05.011

Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4

Autor: Sabine Gröning, Dzmitry Sinitski, Michael Lacy, Aphrodite Kapurniotu, Christos Kontos, Kathleen Hille, Priscila Bourilhon, Georgios Pantouris, Christian Weber, Eric M. Rosenberg, Christine Krammer, Juergen Bernhagen, Markus Brandhofer, Elias Lolis, Maria Bakou, Tharshika Thavayogarajah

Publikováno v: Scientific reports 8, 5171 (2018). doi:10.1038/s41598-018-23554-5
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Scientific Reports, 8:5171. Nature Publishing Group

MIF is a chemokine-like cytokine that plays a role in the pathogenesis of inflammatory and cardiovascular disorders. It binds to the chemokine-receptors CXCR2/CXCR4 to trigger atherogenic leukocyte migration albeit lacking canonical chemokine structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e896ab0590415daef9536e2fd0d2874

A Hot‐Segment‐Based Approach for the Design of Cross‐Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self‐Assembly

Autor: Eleni Malideli, Andrea Caporale, Michael Kracklauer, Karine Farbiarz, Erika Andreetto, Anna Spanopoulou, Tatjana Neumüller, Aphrodite Kapurniotu, Li-Mei Yan, Bernd Reif, Maria Bakou, Gerhard Rammes, Marianna Tatarek-Nossol, Elke Prade

Publikováno v: Angewandte Chemie (Int. ed., Print) 54 (2015): 13095–13100. doi:10.1002/anie.201504973
info:cnr-pdr/source/autori:Andreetto, Erika; Malideli, Eleni; Yan, Li-Mei; Kracklauer, Michael; Farbiarz, Karine; Tatarek-Nossol, Marianna; Rammes, Gerhard; Prade, Elke; Neumueller, Tatjana; Caporale, Andrea; Spanopoulou, Anna; Bakou, Maria; Reif, Bernd; Kapurniotu, Aphrodite/titolo:A Hot-Segment-Based Approach for the Design of Cross-Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self-Assembly/doi:10.1002%2Fanie.201504973/rivista:Angewandte Chemie (Int. ed., Print)/anno:2015/pagina_da:13095/pagina_a:13100/intervallo_pagine:13095–13100/volume:54

The design of inhibitors of protein-protein interactions mediating amyloid self-assembly is a major challenge mainly due to the dynamic nature of the involved structures and interfaces. Interactions of amyloidogenic polypeptides with other proteins a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101355da42e807627e1fd77e2a12e3a1
https://doi.org/10.1002/anie.201504973

Oxidative stress, inflammation and angiogenesis markers in elite female water polo athletes throughout a season

Autor: Evdokia Varamenti, Antonios Kyparos, Stavroula Kalaboka, Aristeidis S. Veskoukis, Athanasios Z. Jamurtas, Dimitrios Kouretas, Maria Bakou, Yiannis Koutedakis

Publikováno v: Food and Chemical Toxicology. 61:3-8

Elite athletes undergo heavy training programs throughout the year. The aim of the present study was to evaluate blood biomarkers of redox status, oxidative stress, inflammation and angiogenesis over the course of a competitive season in elite female

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9d7ad88297af471a5f3f3aa8c35a8b
https://doi.org/10.1016/j.fct.2012.12.001

Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: EVIDENCE FOR PARTIAL ALLOSTERIC AGONISM IN COMPARISON WITH CXCL12 CHEMOKINE

Autor: Deepa, Rajasekaran, Sabine, Gröning, Corinna, Schmitz, Swen, Zierow, Natalie, Drucker, Maria, Bakou, Kristian, Kohl, André, Mertens, Hongqi, Lue, Christian, Weber, Annie, Xiao, Gary, Luker, Aphrodite, Kapurniotu, Elias, Lolis, Jürgen, Bernhagen

Publikováno v: The Journal of biological chemistry. 291(30)

An emerging number of non-chemokine mediators are found to bind to classical chemokine receptors and to elicit critical biological responses. Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine that exhibits chemokine-like activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab7e035ba0ef13f07b415ca9696e8c3c
https://pubmed.ncbi.nlm.nih.gov/27226569