I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations

Autor: Carolyn S Calfee, Michael A Matthay, Paul Henderson, Martin Eklund, Laura J Esserman, Chirag Patel, Angela Haczku, Michelle Jung, Tony Oliver, Alessio Crippa, Andrea Discacciati, Kathleen D Liu, Ellen L Burnham, Nuala J Meyer, Fady A Youssef, Derek W Russell, Julie Lang, Kevin W Gibbs, Daniel C Files, Sheetal Gandotra, Purnema Madahar, Nathan K Cobb, Timothy E Albertson, Rajiv Sonti, John P Reilly, Alejandra Jauregui, Iván García, Luis E Huerta, Daniel Clark Files, Neil R Aggarwal, Adam L Asare, Jeremy R Beitler, Paul A Berger, George Cimino, Melissa H Coleman, Paul T Henderson, Caroline A G Ittner, Kashif T Khan, Jonathan L Koff, Mary LaRose, Joe Levitt, Ruixiao Lu, Jeffrey D McKeehan, Karl W Thomas, Aaron M Mittel, Albert F Yen, Alexis E Suarez, Alexis L Serra, Alpesh N Amin, Amanda Rosen, Amy L Dzierba, Anna D Barker, Ariel R Weisman, Brian M Daniel, Brian M Morrissey, Caroline AG Ittner, Chayse Jones, Christina Creel-Bulos, Christina M Angelucci, Diana Ng, Fredy Chaparro-Rojas, Gavin H Harris, Harsh V Barot, Heny Su, Jacqueline B Sutter, Jamal Dodin, Jerry S Lee, John Kazianis, Joshua F Detelich, Julie E Lang, Justin Muir, Katarzyna Gosek, Katherine L Nugent, Kimberly Yee, Laura G Rodrigues, Laura R Macias, Lindsey A Orr, Lindsie L Boerger, Lissette Rosario-Remigio, Lucia Kufa, Maged Tanios, Maria B Reyes, Max W Adelman, Maya M Juarez, Michelle Meyers, Mitchell P Sternlieb, Neil Aggarwal, Nilam S Mangalmurti, Patrice Jones, Paul L Saban, Peter S Marshall, Philiip A Robinson, Philip Yang, Rahul Nair, Richard Anthony Lee, Richard G Wunderink, Romina Wahab, Roxana A Lupu, Santhi I Kumar, Sara C Auld, Scott Fields, Se Fum Wong, Skyler J Pearson, Spencer Whealon, Timothy F Obermiller, Anita Darmanian, John Schicchi, Esmeralda Martinez, Farjad Sarafian, Julie Nguyen, Bethany Weiler-Lisowski, Jaime Wyatt, Daniel Blevins, Marylee Melendrez, Brenda Lopez, Hiwet Tzehaie, Omowunmi Amosu, Austin Simonson, Erin Hardy, Brett Lindgren, Gregory Peterfreund, Leigha Landreth, Lisa Parks

Publikováno v: BMJ Open, Vol 12, Iss 6 (2022)

Externí odkaz: https://doaj.org/article/480eafc2c901401aa40873075dcf1eb8

Fetal IgG specificities against Trypanosoma cruzi antigens in infected newborns

Autor: Maria B. Reyes, Myriam Lorca, Patricia Munoz, Alberto C.C. Frasch

Publikováno v: Proceedings of the National Academy of Sciences. 87:2846-2850

A panel of Trypanosoma cruzi antigens produced by recombinant DNA techniques was used to analyze the IgM and IgG specificities present in sera from 22 mothers with chronic Chagas disease and their newborn infants. Ten of the newborns were congenitall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8042d940fd29fb905498f23ce957de44
https://doi.org/10.1073/pnas.87.7.2846

Identification of a Trypanosoma cruzi antigen that is shed during the acute phase of Chagas' disease

Autor: Roberto A. Macina, Ulf Pettersson, Maria B. Reyes, JoséL. Affranchino, Carlos F. Ibañez, Lena Åslund, Alejandro O. Luquetti, Anis Rassi, Alberto C.C. Frasch

Publikováno v: Molecular and Biochemical Parasitology. 34:221-228

A Trypanosoma cruzi antigen which is shed into the culture medium by the trypomastigote stage of the parasite and detected in blood of acutely infected mice was cloned and characterized. We designate this antigen shed acute phase antigen (SAPA). Five

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11c3dc28c99c596f9639fa65ea4a748
https://doi.org/10.1016/0166-6851(89)90050-9

Multiple Trypanosoma cruzi antigens containing tandemly repeated amino acid sequence motifs

Autor: Maria B. Reyes, Susana Leguizamon, Roberto A. Macina, Jose L. Affranchino, Carlos F. Ibañez, Lena Åslund, Alberto C.C. Frasch, Mario E. Camargo, Ulf Pettersson

Publikováno v: Molecular and biochemical parasitology. 30(1)

Chromosomal DNA from Trypanosoma cruzi, the agent of the American trypanosomiasis (Chagas' disease), was used for construction of a DNA library, employing the expression vector lambda gt11. Nine clones encoding different parasite antigens were isolat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ddb88d1b2b4aac577fa50af5ec7c62
https://pubmed.ncbi.nlm.nih.gov/3135494