Lower versus higher hemoglobin threshold for transfusion in septic shock

Autor: Lars B, Holst, Nicolai, Haase, Jørn, Wetterslev, Jan, Wernerman, Anne B, Guttormsen, Sari, Karlsson, Pär I, Johansson, Anders, Aneman, Marianne L, Vang, Robert, Winding, Lars, Nebrich, Helle L, Nibro, Bodil S, Rasmussen, Johnny R M, Lauridsen, Jane S, Nielsen, Anders, Oldner, Ville, Pettilä, Maria B, Cronhjort, Lasse H, Andersen, Ulf G, Pedersen, Nanna, Reiter, Jørgen, Wiis, Jonathan O, White, Lene, Russell, Klaus J, Thornberg, Peter B, Hjortrup, Rasmus G, Müller, Morten H, Møller, Morten, Steensen, Inga, Tjäder, Kristina, Kilsand, Suzanne, Odeberg-Wernerman, Brit, Sjøbø, Helle, Bundgaard, Maria A, Thyø, David, Lodahl, Rikke, Mærkedahl, Carsten, Albeck, Dorte, Illum, Mary, Kruse, Per, Winkel, Anders, Perner, J M, Breider

Publikováno v: Holst, L B, Haase, N, Wetterslev, J, Wernerman, J, Guttormsen, A B, Karlsson, S, Johansson, P I, Aneman, A, Vang, M L, Winding, R, Nebrich, L, Nibro, H L, Rasmussen, B S, Lauridsen, J R M, Nielsen, J S, Oldner, A, Pettilä, V, Cronhjort, M B, Andersen, L H, Pedersen, U G, Reiter, N, Wiis, J, White, J O, Russell, L, Thornberg, K J, Hjortrup, P B, Müller, R G, Møller, M H, Steensen, M, Tjäder, I, Kilsand, K, Odeberg-Wernerman, S, Sjøbø, B, Bundgaard, H, Thyø, M A, Lodahl, D, Mærkedahl, R, Albeck, C, Illum, D, Kruse, M, Winkel, P, Perner, A & TRISS Trial Group 2014, ' Lower versus higher hemoglobin threshold for transfusion in septic shock ', The New England Journal of Medicine, vol. 371, no. 15, pp. 1381-91 . https://doi.org/10.1056/NEJMoa1406617
Holst, L B, Haase, N, Wetterslev, J, Wernerman, J, Guttormsen, A B, Karlsson, S, Johansson, P I, Aneman, A, Vang, M L, Winding, R, Nebrich, L, Nibro, H L, Rasmussen, B S, Lauridsen, J R M, Nielsen, J S, Oldner, A, Pettilä, V, Cronhjort, M B, Andersen, L H, Pedersen, U G, Reiter, N, Wiis, J, White, J O, Russell, L, Thornberg, K J, Hjortrup, P B, Müller, R G, Møller, M H, Steensen, M, Tjäder, I, Kilsand, K, Odeberg-Wernerman, S, Sjøbø, B, Bundgaard, H, Thyø, M A, Lodahl, D, Mærkedahl, R, Albeck, C, Illum, D, Kruse, M, Winkel, P, Perner, A & the TRISS Trial Group and the Scandinavian Critical Care Trials Group 2014, ' Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock ', The New England Journal of Medicine, vol. 371, no. 15, pp. 1381-1391 . https://doi.org/10.1056/NEJMoa1406617

BACKGROUND: Blood transfusions are frequently given to patients with septic shock. However, the benefits and harms of different hemoglobin thresholds for transfusion have not been established.METHODS: In this multicenter, parallel-group trial, we ran

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https://pubmed.ncbi.nlm.nih.gov/27686348