Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis

Autor: Aline X.S. Santos, Fabrice P. A. David, Manuele Piccolis, Isabelle Riezman, Maria Auxiliadora Aguilera-Romero, Olivier Schaad, Robbie Loewith, Howard Riezman

Publikováno v: Molecular biology of the cell
Molecular Biology of the Cell, Vol. 25, No 20 (2014) pp. 3234-3246
Molecular Biology of the Cell

An unbiased mass spectrometry–based lipidomic screening method is used to analyze the major lipids of yeast deletions in protein kinase/phosphatase genes. This creates a new, rich source of biological insight. It uncovers new players in lipid homeo

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