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pro vyhledávání: '"Maria Augusta C. Rodrigues"'
Autor:
David J. Ponting, Michelle O. Kenyon, Melisa Masuda-Herrera, Angela White, Robert Thomas, Maria Augusta C. Rodrigues, Joel P. Bercu, Fernanda Waechter, Andreas Czich, George E. Johnson, Kevin P. Cross, Susanne Glowienke
Publikováno v:
Regulatory Toxicology and Pharmacology. 123:104926
The ICH M7(R1) guideline describes a framework to assess the carcinogenic risk of mutagenic and carcinogenic pharmaceutical impurities following less-than-lifetime (LTL) exposures. This LTL framework is important as many pharmaceuticals are not admin