Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Maria Assunta Chiacchio"'
Autor:
Paola Dell’Albani, Claudia Carbone, Giovanni Sposito, Michela Spatuzza, Maria Assunta Chiacchio, Rosaria Grasso, Laura Legnani, Debora Santonocito, Carmelo Puglia, Rosalba Parenti, Giovanni Puglisi, Agatina Campisi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8397 (2024)
Glioblastoma (GBM) is one of the most aggressive cancers, characterized by a decrease in antioxidant levels. Evidence has demonstrated that ferulic acid (FA), a natural antioxidant particularly abundant in vegetables and fruits, could be a promising
Externí odkaz:
https://doaj.org/article/322eedf2ecdf424c90c63f562fa92d06
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4159 (2024)
Schiff bases (SBs) are important ligands in coordination chemistry due to their unique structural properties. Their ability to form complexes with metal ions has been exploited for the environmental detection of emerging water contaminants. In this w
Externí odkaz:
https://doaj.org/article/064e45b6861641629fbe68f7d8c0e2b7
Autor:
Avisa Maleki, Elena Crispino, Serena Anna Italia, Valentina Di Salvatore, Maria Assunta Chiacchio, Fianne Sips, Roberta Bursi, Giulia Russo, Davide Maimone, Francesco Pappalardo
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3081-3090 (2023)
Multiple sclerosis is an autoimmune inflammatory disease that affects the central nervous system through chronic demyelination and loss of oligodendrocytes. Since the relapsing-remitting form is the most prevalent, relapse-reducing therapies are a pr
Externí odkaz:
https://doaj.org/article/ba08fa880ed64faeb056e96e943b35f2
Autor:
Maria Assunta Chiacchio, Laura Legnani
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1298 (2024)
The present review contains a representative sampling of mechanistic studies, which have appeared in the literature in the last 5 years, on 1,3-dipolar cycloaddition reactions, using DFT calculations. Attention is focused on the mechanistic insights
Externí odkaz:
https://doaj.org/article/25089923c36f44529347b5edd802c172
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 9, Pp 104063- (2022)
In this paper, we report a mechanistic study of RuO4-catalyzed oxidation on the 2-methylisoxazolidine through computational methods. The investigation was performed taken into consideration that the oxidation could take place on different sites of th
Externí odkaz:
https://doaj.org/article/ad23a24f25f249da89d486513286a5a0
Autor:
Maria Assunta Chiacchio, Laura Legnani, Enrico Mario Alessandro Fassi, Gabriella Roda, Giovanni Grazioso
Publikováno v:
Molecules, Vol 28, Iss 6, p 2866 (2023)
Boron containing compounds (BCCs) aroused increasing interest in the scientific community due to their wide application as drugs in various fields. In order to design new compounds hopefully endowed with pharmacological activity and also investigate
Externí odkaz:
https://doaj.org/article/82492f3d056046e5a9023a890cb68332
Autor:
Agata Campisi, Roberta Bonfanti, Giuseppina Raciti, Gabriele Bonaventura, Laura Legnani, Gaetano Magro, Marzio Pennisi, Giulia Russo, Maria Assunta Chiacchio, Francesco Pappalardo, Rosalba Parenti
Publikováno v:
Molecular Therapy: Oncolytics, Vol 16, Iss , Pp 197-206 (2020)
Herein, we assess the gene expression changes activated in thyroid tumors through a computational approach, using the MapReduce algorithm. Through this predictive analysis, we identified the TfR1 gene as a critical mediator of thyroid tumor progressi
Externí odkaz:
https://doaj.org/article/32dc32c77a6745bfb0038dcc25987112
Autor:
Consuelo Celesti, Daniela Iannazzo, Claudia Espro, Annamaria Visco, Laura Legnani, Lucia Veltri, Giuseppa Visalli, Angela Di Pietro, Paola Bottino, Maria Assunta Chiacchio
Publikováno v:
Materials, Vol 15, Iss 22, p 8208 (2022)
Hybrid hydrogels composed of chitosan (CS) have shown great potential in bone tissue engineering and regeneration. The introduction of polyhedral oligomeric silsesquioxanes (POSS) in the biopolymeric matrix has been demonstrated to improve the rheolo
Externí odkaz:
https://doaj.org/article/357c758fd5014d82b5f8a98ce3858d1a
Autor:
Manuel Pedrón, Laura Legnani, Maria-Assunta Chiacchio, Pierluigi Caramella, Tomás Tejero, Pedro Merino
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1552-1562 (2019)
The ruthenium tetroxide-mediated oxidation of cyclopentane, tetrahydrofuran, tetrahydrothiophene and N-substituted pyrrolidines has been studied computationally by DFT and topological (analysis of the electron localization function, ELF) methods. In
Externí odkaz:
https://doaj.org/article/337ec88d7a06492b8120caa3aed7fd75
Autor:
Laura Legnani, Salvatore V. Giofré, Daniela Iannazzo, Consuelo Celesti, Lucia Veltri, Maria Assunta Chiacchio
Publikováno v:
Molecules, Vol 27, Iss 17, p 5390 (2022)
The direct oxidation reaction of isoxazolidines plays an important role in organic chemistry, leading to the synthesis of biologically active compounds. In this paper, we report a computational mechanistic study of RuO4-catalyzed oxidation of differe
Externí odkaz:
https://doaj.org/article/e07a83ed0463470f915bc3509c487c4e