Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Maria Antonietta Stasi"'
Autor:
Carlo Tallarico, Elena Cini, Silvia Pace, Giuseppe Giannini, Francesco Manera, Rita De Santis, Loredana Vesci, Maria Antonietta Stasi, Ferdinando Maria Milazzo, Elena Petricci, Fabrizio Manetti
Small series of acylguanidine and acylthiourea derivatives were synthesized in gram-scale and assayed for their ability to modulate the Hh signalling pathway. In vitro studies showed a low micromolar inhibitory activity toward tumor cell lines, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9df7475996f039d0a7b4021640421d0
http://hdl.handle.net/11365/1064674
http://hdl.handle.net/11365/1064674
Autor:
Mario Vertechy, Silvia Pace, Katia Lombardo, Franco Borsini, Antonio Caprioli, Patrizia Minetti, Stefano Di Serio, Teresa Riccioni, Maria Antonietta Stasi
Publikováno v:
European Journal of Pharmacology. 761:353-361
Antagonism of the adenosine A2A receptor represents a promising strategy for non-dopaminergic treatment of Parkinson׳s disease (PD). Previously, the adenosine A2A receptor antagonist ST1535 was shown to possess potential beneficial effects in animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d94e60d0c6c32b04bde35bf74401a2
https://doi.org/10.1016/j.ejphar.2015.03.070
https://doi.org/10.1016/j.ejphar.2015.03.070
Autor:
Daniela Pesce, Daniela Santapaola, Liliana Ferrari, Anna M. Alfano, Giancarlo Gramiccioli, Giovanni Paganelli, Anna Maria Anastasi, Fiorella Petronzelli, Angela Pelliccia, Rita De Santis, Maria Antonietta Stasi, Antonio Rosi, Barbara Leoni, Claudio Albertoni
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 109:145-155
We recently described an oxidized avidin variant, named AvidinOX®, which is a product that chemically links to tissue proteins while maintaining the capacity to uptake intravenously administered biotin. Such product proved to be successful in target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d98465c5414fd2f12249e34bf5dd987b
https://doi.org/10.1111/j.1742-7843.2011.00701.x
https://doi.org/10.1111/j.1742-7843.2011.00701.x
Publikováno v:
European Journal of Pharmacology. 621:53-60
ST2472, namely (9-piperazin-1-ylpyrrolo [2,1]-b[1,3]benzothiazepine), was previously shown to have antipsychotic activity in the conditioned avoidance response (CAR) test. In the present work we aimed at evaluating the antipsychotic potential of ST24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b0d6ae23d26e57c947047c3e84cfcf0
https://doi.org/10.1016/j.ejphar.2009.08.035
https://doi.org/10.1016/j.ejphar.2009.08.035
Publikováno v:
Psychopharmacology. 200:157-165
Polydipsia is a severe complication of long-term schizophrenia and, despite its unknown pathogenesis, is empirically treated with typical or atypical antipsychotics. In the rat, nonregulatory water intake is induced by repeated administration of amph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73f4c83b3d4c26aa6bab6a2cc81f4ab
https://doi.org/10.1007/s00213-008-1229-1
https://doi.org/10.1007/s00213-008-1229-1
Autor:
Carlo Tallarico, Patrizia Minetti, Simone Lucarini, Francesca Bartoccini, Michele Bassi, Federica Vacondio, Francesca Capocasa, Pietro Grossi, Francesco Manera, Giandomenico Brogin, Teresa Riccioni, Silvia Pace, Franco Borsini, Giorgio Tarzia, Maria Antonietta Stasi, Giovanni Piersanti, Walter Cabri
Inhibition of adenosine A2A receptors has been shown to elicit a therapeutic response in preclinical animal models of Parkinson's disease (PD). We previously identified the triazolo-9H-purine, ST1535, as a potent A(2A)R antagonist. Studies revealed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b673ef244e177a5845a09fa10895219
http://hdl.handle.net/11585/756673
http://hdl.handle.net/11585/756673
Autor:
Filomena Fezza, Stefania Butini, Giuseppe Borrelli, Stefano Di Serio, Silvia Vincenti, Antonio Caprioli, Samuele Maramai, Giuseppe Campiani, Mauro Maccarrone, Grazia Gallo, Margherita Brindisi, Sandra Gemma, Walter Cabri, Emanuela Talamonti, Sindu Ros, Franco Borsini, Patrizia Minetti, Maria Antonietta Stasi
Fatty acid amide hydrolase (FAAH, EC 3.5.1.99) is the main enzyme catabolizing endocannabinoid fatty acid amides. FAAH inactivation promotes beneficial effects upon pain and anxiety without the side effects accompanying agonists of type-1 cannabinoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff2174021bc05c27c215f18d35616fc
http://hdl.handle.net/11697/155949
http://hdl.handle.net/11697/155949
Autor:
Gaetano Arcuri, Daniela Passeri, Katia Lombardo, Elena Doldo, Paolo Fociani, Roberto Camerini, Franco Borsini, Maria Antonietta Stasi, Maria Giovanna Scioli, Gaetana Costanza, Augusto Orlandi, Silvia Pace
Publikováno v:
Clinical and Translational Gastroenterology
Objectives: Microvascular endothelial dysfunction characterizes ulcerative colitis (UC), the most widespread form of inflammatory bowel disease. Intestinal mucosal microvessels in UC display aberrant expression of cell adhesion molecules (CAMs) and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8ead0b444f4fec227166b84d768a65
https://pubmed.ncbi.nlm.nih.gov/24646507
https://pubmed.ncbi.nlm.nih.gov/24646507
Autor:
Marco Mor, Teresa Riccioni, Silvia Rivara, Patrizia Minetti, Francesca Bartoccini, Franco Borsini, Giorgio Tarzia, Giuseppe Diamantini, Maria Antonietta Stasi, Daniele Pala, Giovanni Piersanti, Walter Cabri
Publikováno v:
Journal of medicinal chemistry. 56(3)
A systematic modification of the caffeinyl core and substituents of the reference compound (E)-8-(3-chlorostyryl)caffeine led to the 9-deazaxanthine derivative (E)-6-(4-chlorostyryl)-1,3,5,-trimethyl-1H-pyrrolo[3,2-d]pyrimidine-2,4-(3H,5H)-dione (17f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae59d5b14ee4b7a17d31786f1e01616
https://pubmed.ncbi.nlm.nih.gov/23281824
https://pubmed.ncbi.nlm.nih.gov/23281824
Autor:
Paolo Nencini, Ottaviano Serlupi-Crescenzi, Franco Borsini, Maria Antonietta Stasi, Lorenza De Carolis
The biological underpinnings of schizophrenic polydipsia are poorly understood. This study is aimed at fulfilling the requisites of an experimental model of this syndrome through the quinpirole (QNP) induction of non-regulatory drinking in rats. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3afb015abe4b1a795cc03ad76c61d8c
http://hdl.handle.net/11573/89118
http://hdl.handle.net/11573/89118