Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Maria Angelica Grillo"'
Autor:
Antonio Toninello, Silvia Grancara, Vito Di Noto, Pamela Martinis, Lisa Dalla Via, Stefania Saccoccio, Valentina Battaglia, Marcantonio Bragadin, Maria Angelica Grillo, Enzo Agostinelli
Publikováno v:
Amino Acids. 42:761-768
Agmatine, a divalent diamine with two positive charges at physiological pH, is transported into the matrix of liver mitochondria by an energy-dependent mechanism, the driving force of which is the electrical membrane potential. Its binding to mitocho
Autor:
Valentina Battaglia, Antonio Toninello, Sebastiano Colombatto, A.R. Simonian, A. R. Khomutov, Maria Angelica Grillo, Carlo Alberto Rossi, Mauro Salvi
Publikováno v:
Università degli Studi di Padova-IRIS
The charge of the agmatine analogues AO-Agm [N-(3-aminooxypropyl)guanidine], GAPA [N-(3-aminopropoxy)guanidine] and NGPG [N-(3-guanidinopropoxy)guanidine] is deficient as compared with that of agmatine and they are thus able to inhibit agmatine trans
Autor:
S.P. Solinas, Giovanni Testore, Carlo Cravanzola, Riccardo Autelli, Laura Morando, Maria Angelica Grillo, Giulia Gardini, Roberta Cesa, Giuliana Muzio, Sebastiano Colombatto
Publikováno v:
Journal of Hepatology. 39:793-799
Background/Aims : Previous experiments have shown that agmatine, the product of arginine decarboxylase, is transported in competition with putrescine into quiescent rat hepatocytes, where it promotes several effects, including marked decrease of intr
Autor:
Antonio Toninello, Sebastiano Colombatto, Giulio Clari, Maria Angelica Grillo, Luciana Bordin, Anna Maria Brunati, Mauro Salvi, Cristina Vargiu
Publikováno v:
Biochemical and Biophysical Research Communications. 290:463-468
Cytosolic spermidine/spermine acetyltransferase (SSAT) catalyzes the acetylation of the N 1 -propylamino groups of spermine and spermidine. The enzyme has a very short half-life and is rapidly induced by various stimuli. Once acetylated, these polyam
Autor:
Carlo Cravanzola, Claudia Cabella, Sebastiano Colombatto, Cristina Vargiu, Sabina Belliardo, Maria Angelica Grillo
Publikováno v:
European Journal of Biochemistry. 259:933-938
Agmatine has been proposed as the physiological ligand for the imidazoline receptors. It is not known whether it is also involved in the homoeostasis of intracellular polyamine content. To show whether this is the case, we have studied the effect of
Autor:
Davide Corpillo, Bedino S, Giulia Gardini, Sebastiano Colombatto, Giovanni Testore, Carlo Cravanzola, S.P. Solinas, Maria Angelica Grillo, Claudia Cabella, Cristina Vargiu
Publikováno v:
European Journal of Biochemistry. 268:940-947
Rat hepatocytes in culture take up [14C]-agmatine by both a high-affinity transport system [KM = 0.03 mM; Vmax = 30 pmol x min x (mg protein)-1] and a low-affinity system. The high-affinity system also transports putrescine, but not cationic amino ac
Autor:
Romana Hochreiter, Maria Angelica Grillo, Anton Hermann, Thresia Thomas, Sebastiano Colombatto, Claudia Cabella, Thomas Weiger, Thierry Langer, Wilhelm Heidegger
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 361:235-246
A series of diamines with the general structure NH2(CH2) x NH2, x=2–12, was tested for their potential effects on cell proliferation of cultured rat C6 glioma cells in comparison to natural polyamines. Long chain diamines reduced cell number after
Autor:
Giulio Clari, Giovanni Testore, Maria Angelica Grillo, Sebastiano Colombatto, Cristina Vargiu, Luciana Bordin, Antonio Toninello
Publikováno v:
Biochemical and Biophysical Research Communications. 229:845-851
Casein kinase 2 purified from human erythrocyte cytosol has been found to phosphorylate human spermidine/spermine N 1 -acetyltransferase (SSAT) expressed as a fusion protein in E. coli and purified to homogeneity with a specific activity similar to t
Publikováno v:
Cell Biochemistry and Function. 14:173-180
Uptake of polyamines has been investigated extensively in many cells, but not in placenta, where the polyamine– polyamine oxidase system is supposed to have an immunoregulatory function in pregnancy. Due to the importance of the transfer in this ti
Autor:
Valentina Battaglia, Marcantonio Bragadin, Francesca Zonta, Antonio Toninello, Pamela Martinis, Elena Tibaldi, Silvia Grancara, Anna Maria Brunati, Maria Angelica Grillo, Enzo Agostinelli, G. Tempera
Publikováno v:
Amino Acids
Amino Acids, Springer Verlag, 2012, 42 (2-3), pp.741-9. ⟨10.1007/s00726-011-0990-3⟩
Amino Acids, Springer Verlag, 2012, 42 (2-3), pp.741-9. ⟨10.1007/s00726-011-0990-3⟩
International audience; The polyamine spermine is transported into the matrix of various types of mitochondria by a specific uniporter system identified as a protein channel. This mechanism is regulated by the membrane potential; other regulatory eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1091d9a8ece0fa88fd0d8d8e9f03afd3
http://hdl.handle.net/10278/29259
http://hdl.handle.net/10278/29259