CCL2-expressing astrocytes mediate the extravasation of T lymphocytes in the brain. Evidence from patients with glioma and experimental models in vivo.

Autor: Maria Angeles Carrillo-de Sauvage, Aurora Gómez, Carmen María Ros, Francisco Ros-Bernal, Eduardo D Martín, Ana Perez-Vallés, José M Gallego-Sanchez, Emiliano Fernández-Villalba, Carlos Barcia, Maria-Trinidad Herrero

Publikováno v: PLoS ONE, Vol 7, Iss 2, p e30762 (2012)

CCL2 is a chemokine involved in brain inflammation, but the way in which it contributes to the entrance of lymphocytes in the parenchyma is unclear. Imaging of the cell type responsible for this task and details on how the process takes place in vivo

Externí odkaz: https://doaj.org/article/87bd5119e76946b18f59746465826932

Astrocytes réactifs et maladies cérébrales

Autor: Yiannis Poulot-Becq-Giraudon, Maria-Angeles Carrillo-de Sauvage, Carole Escartin

Publikováno v: médecine/sciences. 38:786-794

Les astrocytes sont des partenaires essentiels des neurones dans le système nerveux central. En réponse à de nombreuses maladies qui touchent le cerveau, les astrocytes subissent des modifications morphologiques, moléculaires et fonctionnelles :

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28896ca6342ea97739549a4dfd27ff7b
https://doi.org/10.1051/medsci/2022104

Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease

Autor: Martine Guillermier, Carole Escartin, Océane Guillemaud, Alexis-Pierre Bemelmans, Charlène Joséphine, Gilles Bonvento, Emmanuel Brouillet, Kelly Ceyzériat, Thomas Saint-Georges, Philippe Hantraye, Maria-Angeles Carrillo-de Sauvage, Karine Cambon, Sueva Bernier, Fanny Petit, Lucile Ben Haim, Anne-Sophie Hérard

Publikováno v: Neurobiology of Aging
Neurobiology of Aging, Elsevier, 2020, 90, pp.135-146. ⟨10.1016/j.neurobiolaging.2020.02.010⟩
Neurobiology of Aging, 2020, 90, pp.135-146. ⟨10.1016/j.neurobiolaging.2020.02.010⟩

In Alzheimer disease (AD), astrocytes undergo complex changes and become reactive. The consequences of this reaction are still unclear. To evaluate the net impact of reactive astrocytes in AD, we recently developed viral vectors targeting astrocytes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b28753aa9921b953676af06fa844c9
https://doi.org/10.1016/j.neurobiolaging.2020.02.010

Questions and (some) answers on reactive astrocytes

Autor: Carole Escartin, Océane Guillemaud, Maria-Angeles Carrillo-de Sauvage

Publikováno v: Glia
Glia, Wiley, 2019, ⟨10.1002/glia.23687⟩
Glia, 2019, ⟨10.1002/glia.23687⟩

Astrocytes are key cellular partners for neurons in the central nervous system. Astrocytes react to virtually all types of pathological alterations in brain homeostasis by significant morphological and molecular changes. This response was classically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53293c605c8bdb3b01d35124ad9bc01b
https://doi.org/10.1002/glia.23687

Diffusion-weighted magnetic resonance spectroscopy enables cell-specific monitoring of astrocyte reactivity $in\ vivo$

Autor: Gilles Bonvento, Edwin Hernández-Garzón, Julien Valette, Carole Escartin, Julien Flament, Maria-Angeles Carrillo-de Sauvage, Clémence Ligneul, Marco Palombo, Emmanuel Brouillet, Philippe Hantraye

Publikováno v: NeuroImage
NeuroImage, Elsevier, 2019, 191, pp.457-469. ⟨10.1016/j.neuroimage.2019.02.046⟩
NeuroImage, 2019, 191, pp.457-469. ⟨10.1016/j.neuroimage.2019.02.046⟩

International audience; Reactive astrocytes exhibit hypertrophic morphology and altered metabolism. Deciphering astrocytic status would be of great importance to understand their role and dysregulation in pathologies, but most analytical methods rema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc37564ddcfc38eca866c4736092f138
https://hal-cea.archives-ouvertes.fr/cea-02155405