Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Maria Andres‐Alonso"'
Autor:
Maria Andres-Alonso, Maximilian Borgmeyer, Hadi Mirzapourdelavar, Jakob Lormann, Kim Klein, Michaela Schweizer, Sabine Hoffmeister-Ullerich, Anja M. Oelschlegel, Alexander Dityatev, Michael R. Kreutz
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112692- (2023)
Summary: The complex cytoarchitecture of neurons poses significant challenges for the maturation of synaptic membrane proteins. It is currently unclear whether locally secreted synaptic proteins bypass the Golgi or whether they traffic through Golgi
Externí odkaz:
https://doaj.org/article/cc25592f2ad74310b045450eed535d52
Autor:
Maria Andres-Alonso, Mohamed Raafet Ammar, Ioana Butnaru, Guilherme M. Gomes, Gustavo Acuña Sanhueza, Rajeev Raman, PingAn Yuanxiang, Maximilian Borgmeyer, Jeffrey Lopez-Rojas, Syed Ahsan Raza, Nicola Brice, Torben J. Hausrat, Tamar Macharadze, Silvia Diaz-Gonzalez, Mark Carlton, Antonio Virgilio Failla, Oliver Stork, Michaela Schweizer, Eckart D. Gundelfinger, Matthias Kneussel, Christina Spilker, Anna Karpova, Michael R. Kreutz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
There is growing evidence that autophagy might serve specialized functions in neurons besides its role in protein homeostasis. In this study, authors demonstrate that axonal retrograde transport of BDNF/TrkB in neuronal amphisomes is involved in plas
Externí odkaz:
https://doaj.org/article/8405b7ea05e8461086f8fdd56ee7dec8
Autor:
Vesna Lazarevic, Sandra Fieńko, Maria Andres-Alonso, Daniela Anni, Daniela Ivanova, Carolina Montenegro-Venegas, Eckart D. Gundelfinger, Michael A. Cousin, Anna Fejtova
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Despite the central role of amyloid β (Aβ) peptide in the etiopathogenesis of Alzheimer’s disease (AD), its physiological function in healthy brain is still debated. It is well established that elevated levels of Aβ induce synaptic depression an
Externí odkaz:
https://doaj.org/article/e4dc721102d84b10975c005a9b87b42b
Autor:
Maria Andres-Alonso, Katarzyna M. Grochowska, Eckart D. Gundelfinger, Anna Karpova, Michael R. Kreutz
Publikováno v:
Molecular and cellular neuroscience 125, 103854 (2023). doi:10.1016/j.mcn.2023.103854
The extreme length of neuronal processes poses a challenge for synapse-to-nucleus communication. In response to this challenge several different mechanisms have evolved in neurons to couple synaptic activity to the regulation of gene expression. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708faf9276945b4ccd6be28ce138ca5a
Autor:
Debarpan Guhathakurta, Anna Fejtova, Tobias Huth, Julia Klueva, Stefanie Zeitler, Eva-Maria Weiss, Maria Andres-Alonso, Yagiz Enes Akdas, Daniela Anni
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and molecular life sciences, 78(11):4973-4992
Cellular and molecular life sciences, 78(11):4973-4992
Amyloid beta (Aβ) is linked to the pathology of Alzheimer’s disease (AD). At physiological concentrations, Aβ was proposed to enhance neuroplasticity and memory formation by increasing the neurotransmitter release from presynapse. However, the ex
Autor:
Carolina Montenegro‐Venegas, Debarpan Guhathakurta, Eneko Pina‐Fernandez, Maria Andres‐Alonso, Florian Plattner, Eckart D Gundelfinger, Anna Fejtova
Publikováno v:
EMBO reports, 23(8):e53659
Neuronal presynaptic terminals contain hundreds of neurotransmitter-filled synaptic vesicles (SVs). The morphologically uniform SVs differ in their release competence segregating into functional pools that differentially contribute to neurotransmissi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5dd7dbad444ce6b885aeb819177b94d
https://repository.publisso.de/resource/frl:6434807
https://repository.publisso.de/resource/frl:6434807
Publikováno v:
The EMBO journal, 41(7):e110057
The EMBO journal 41(7), e110057 (2022). doi:10.15252/embj.2021110057
The EMBO journal 41(7), e110057 (2022). doi:10.15252/embj.2021110057
Synaptic function crucially relies on the constant supply and removal of neuronal membranes. The morphological complexity of neurons poses a significant challenge for neuronal protein transport since the machineries for protein synthesis and degradat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa05bd6d8bb51a27119bc0d73478ae71
https://www.embopress.org/doi/full/10.15252/embj.2021110057#support-information-section
https://www.embopress.org/doi/full/10.15252/embj.2021110057#support-information-section
Autor:
Eckart D. Gundelfinger, Carolina Montenegro-Venegas, Vesna Lazarevic, Florian Plattner, Maria Andres-Alonso, Eneko Pina-Fernández, Debarpan Guhathakurta, Anna Fejtova
Neuronal presynaptic terminals contain hundreds of neurotransmitter-filled synaptic vesicles (SVs). The morphologically uniform SVs differ in their release competence segregating into functional pools that differentially contribute to neurotransmissi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8b0fef90a473afeb00f700f3516e2de
https://doi.org/10.1101/2021.07.22.453360
https://doi.org/10.1101/2021.07.22.453360
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and molecular life sciences, 78(6):2621-2639
Cellular and molecular life sciences 78(6), 2621-2639 (2021). doi:10.1007/s00018-020-03722-5
Cellular and molecular life sciences, 78(6):2621-2639
Cellular and molecular life sciences 78(6), 2621-2639 (2021). doi:10.1007/s00018-020-03722-5
The complex morphology of neurons, the specific requirements of synaptic neurotransmission and the accompanying metabolic demands create a unique challenge for proteostasis. The main machineries for neuronal protein synthesis and degradation are loca
Autor:
Rebecca Constance Varatharajah, Hadleigh Cuthbert, Christopher H. Yeo, Maria Andres-Alonso, John Ballard, Michael Longley
Publikováno v:
Neuroscience. 462
The geometry of the glutamatergic mossy-parallel fibre and climbing fibre inputs to cerebellar cortical Purkinje cells has powerfully influenced thinking about cerebellar functions. The compartmentation of the cerebellum into parasagittal zones, iden