Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maria Ahn"'
Autor:
S Wedge, Roger J. Griffin, Maria Ahn, Karen Haggerty, Juan Castro, Ian R. Hardcastle, Celine Cano, Christopher N. Johnson, Bernard T. Golding, Herbie Newell, Steven Howard, Luke Bevan, Timothy J. Blackburn, Pamela A. Williams, Martin E.M. Noble, Yan Zhao, Judith Reeks, Ruth H. Bawn, Neil Thompson, Emiliano Tamanini, Ben Cons, Huw Thomas, Lynsey Fazal, Hugh Walton, Elaine Willmore, Sarah J. Cully, Gianni Chessari, Keisha Hearn, Ildiko Maria Buck
Publikováno v:
Cancer Research. 78:1652-1652
In response to cellular stress, the p53 tumor suppressor is activated to modulate cell cycle progression, DNA repair, and cell death. The activity of p53 is tightly regulated by MDM2, an E3 ubiquitin ligase that targets p53 for proteasomal degradatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f11828bba8837e5bc77a00d94f5218f
https://doi.org/10.1158/1538-7445.am2018-1652
https://doi.org/10.1158/1538-7445.am2018-1652
Autor:
Carmela Ciardullo, Yan Zhao, Martin E.M. Noble, Steven Howard, Maria Ahn, Elaine Willmore, Gianni Chessari, Huw D. Thomas, Ian R. Hardcastle, Laura Woodhouse, John Lunec, Steve R. Wedge, Lynsey Fazal
Publikováno v:
Cancer Research. 78:1870-1870
We investigated the cellular response to two MDM2-p53 antagonists (RG7388 and Cpd 1) in a panel of 19 tumor cell lines and in patient-derived chronic lymphocytic leukemia (CLL) cells. RG7388 (Idasanutlin) is an MDM2-p53 antagonist developed by Roche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41fee78739df33484b76f05a28b94200
https://doi.org/10.1158/1538-7445.am2018-1870
https://doi.org/10.1158/1538-7445.am2018-1870
Publikováno v:
The American Surgeon. 73:508-510
A distinctive case of primary biliary lymphoma occurring in the cystic duct causing extrinsic compression of the porta hepatis in a 48-year-old woman is presented. Imaging studies revealed stricture of the common hepatic duct with a 2.5-cm nonhomogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de47d3266a349e8644bc49d797011719
https://doi.org/10.1177/000313480707300517
https://doi.org/10.1177/000313480707300517
Publikováno v:
The American surgeon. 73(5)
A distinctive case of primary biliary lymphoma occurring in the cystic duct causing extrinsic compression of the porta hepatis in a 48-year-old woman is presented. Imaging studies revealed stricture of the common hepatic duct with a 2.5-cm nonhomogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73a80f4ff5872ac8c1d365981eb91c97
https://pubmed.ncbi.nlm.nih.gov/17521008
https://pubmed.ncbi.nlm.nih.gov/17521008
Autor:
Maria Ahn, George Ward, Christopher N. Johnson, Gianni Chessari, Neil Thompson, Jon Lewis, Pamela A. Williams, Keisha Hearn
Publikováno v:
Molecular Cancer Therapeutics. 12:A55-A55
The inhibitor of apoptosis proteins (IAP) are key regulators of anti-apoptotic and pro-survival signaling pathways. Overexpression of IAPs occurs in various cancers and has been associated with tumor progression and resistance to treatment. IAP antag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::140966549a36f17628bb6b7801d39941
https://doi.org/10.1158/1535-7163.targ-13-a55
https://doi.org/10.1158/1535-7163.targ-13-a55
Autor:
Madlen Hubert, Elin Larsson, Naga Venkata Gayathri Vegesna, Maria Ahnlund, Annika I Johansson, Lindon WK Moodie, Richard Lundmark
Publikováno v:
eLife, Vol 9 (2020)
Caveolae are bulb-shaped invaginations of the plasma membrane (PM) that undergo scission and fusion at the cell surface and are enriched in specific lipids. However, the influence of lipid composition on caveolae surface stability is not well describ
Externí odkaz:
https://doaj.org/article/464ee09725cb4eab999f68a395c71564
Autor:
Ogonna Obudulu, Niklas Mähler, Tomas Skotare, Joakim Bygdell, Ilka N. Abreu, Maria Ahnlund, Madhavi Latha Gandla, Anna Petterle, Thomas Moritz, Torgeir R. Hvidsten, Leif J. Jönsson, Gunnar Wingsle, Johan Trygg, Hannele Tuominen
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-18 (2018)
Abstract Background Secretory Carrier-Associated Membrane Proteins (SCAMPs) are highly conserved 32–38 kDa proteins that are involved in membrane trafficking. A systems approach was taken to elucidate function of SCAMPs in wood formation of Populus
Externí odkaz:
https://doaj.org/article/78a1a9bb1b594750a0e0a40c417a2a22
Autor:
Ken Keefover-Ring, Maria Ahnlund, Ilka Nacif Abreu, Stefan Jansson, Thomas Moritz, Benedicte Riber Albrectsen
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e107189 (2014)
Salicinoids are well-known defense compounds in salicaceous trees and careful screening at the population level is warranted to fully understand their diversity and function. European aspen, Populus tremula, is a foundation species in Eurasia and hig
Externí odkaz:
https://doaj.org/article/897294b8d25e44af98acdc48eb0535d1