Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Maria Agnese Della-Fazia"'
Autor:
Nicola Di-Iacovo, Simona Ferracchiato, Stefania Pieroni, Damiano Scopetti, Marilena Castelli, Danilo Piobbico, Luca Pierucci, Marco Gargaro, Davide Chiasserini, Giuseppe Servillo, Maria Agnese Della-Fazia
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4600 (2024)
TP53 mutations are prevalent in various cancers, yet the complexity of apoptotic pathway deregulation suggests the involvement of additional factors. HOPS/TMUB1 is known to extend the half-life of p53 under normal and stress conditions, implying a re
Externí odkaz:
https://doaj.org/article/f15a8450055041b096aa8f3ddc779a49
Autor:
Nicola Di-Iacovo, Stefania Pieroni, Danilo Piobbico, Marilena Castelli, Damiano Scopetti, Simona Ferracchiato, Maria Agnese Della-Fazia, Giuseppe Servillo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1176 (2023)
The physiological importance of the liver is demonstrated by its unique and essential ability to regenerate following extensive injuries affecting its function. By regenerating, the liver reacts to hepatic damage and thus enables homeostasis to be re
Externí odkaz:
https://doaj.org/article/ed986642b37148c48fcd24ba9150fcd0
Autor:
Stefania Pieroni, Marilena Castelli, Danilo Piobbico, Simona Ferracchiato, Damiano Scopetti, Nicola Di-Iacovo, Maria Agnese Della-Fazia, Giuseppe Servillo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14480 (2022)
A cancer outcome is a multifactorial event that comes from both exogenous injuries and an endogenous predisposing background. The healthy state is guaranteed by the fine-tuning of genes controlling cell proliferation, differentiation, and development
Externí odkaz:
https://doaj.org/article/9d4ccc7461164545aa18456d98b26a7c
Autor:
Simona Ferracchiato, Nicola Di-Iacovo, Damiano Scopetti, Danilo Piobbico, Marilena Castelli, Stefania Pieroni, Marco Gargaro, Giorgia Manni, Stefano Brancorsini, Maria Agnese Della-Fazia, Giuseppe Servillo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7186 (2021)
HOPS is a ubiquitin-like protein implicated in many aspects of cellular function including the regulation of mitotic activity, proliferation, and cellular stress responses. In this study, we focused on the complex relationship between HOPS and the tu
Externí odkaz:
https://doaj.org/article/edf69071c86e48ec9c8702e3234ca0ed
Autor:
Marilena Pariano, Stefania Pieroni, Antonella De Luca, Rossana G. Iannitti, Monica Borghi, Matteo Puccetti, Stefano Giovagnoli, Giorgia Renga, Fiorella D’Onofrio, Marina M. Bellet, Claudia Stincardini, Maria Agnese Della-Fazia, Giuseppe Servillo, Frank L. van de Veerdonk, Claudio Costantini, Luigina Romani
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6531 (2021)
Inflammasomes are powerful cytosolic sensors of environmental stressors and are critical for triggering interleukin-1 (IL-1)-mediated inflammatory responses. However, dysregulation of inflammasome activation may lead to pathological conditions, and t
Externí odkaz:
https://doaj.org/article/f10bebaaca994d7398b3e7c72cdd8f0c
Autor:
Marina Maria Bellet, Claudia Stincardini, Claudio Costantini, Marco Gargaro, Stefania Pieroni, Marilena Castelli, Danilo Piobbico, Paolo Sassone-Corsi, Maria Agnese Della-Fazia, Luigina Romani, Giuseppe Servillo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 2974 (2021)
The circadian clock driven by the daily light–dark and temperature cycles of the environment regulates fundamental physiological processes and perturbations of these sophisticated mechanisms may result in pathological conditions, including cancer.
Externí odkaz:
https://doaj.org/article/258b7d2949f34c6f8ee5ac84a169db8f
Publikováno v:
Cell Stress, Vol 2, Iss 7, Pp 162-175 (2018)
The liver has a unique ability of regenerating after injuries or partial loss of its mass. The mechanisms responsible for liver regeneration – mostly occurring when the hepatic tissue is damaged or functionally compromised by metabolic stress – h
Externí odkaz:
https://doaj.org/article/7804769871c34977b042c8636284dd36
Autor:
Marlene Cervantes, Robert G. Lewis, Maria Agnese Della-Fazia, Emiliana Borrelli, Paolo Sassone-Corsi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(11)
Significance We analyzed the liver metabolome of mice deficient in the expression of the dopamine D2 receptor (D2R) in striatal medium spiny neurons (iMSN-D2RKO) and found profound changes in the liver circadian metabolome compared to control mice. A
Autor:
Luigina Romani, Maria Agnese Della-Fazia, Giuseppe Servillo, Marilena Castelli, Stefania Pieroni, Marina M. Bellet, Francesca Fallarino, Danilo Piobbico
Publikováno v:
Cell Death and Disease, Vol 11, Iss 10, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
HOPS/Tmub1 is a ubiquitously expressed transmembrane ubiquitin-like protein that shuttles between nucleus and cytoplasm during cell cycle progression. HOPS causes cell cycle arrest in G0/G1 phase, an event associated to stabilization of p19Arf, an im
Autor:
Frank L. van de Veerdonk, Rossana G. Iannitti, Stefano Giovagnoli, Stefania Pieroni, Antonella De Luca, Giuseppe Servillo, Marilena Pariano, Maria Agnese Della-Fazia, Luigina Romani, Claudio Costantini, Fiorella D’Onofrio, Monica Borghi, Claudia Stincardini, Marina M. Bellet, Giorgia Renga, Matteo Puccetti
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 22
International Journal of Molecular Sciences, Vol 22, Iss 6531, p 6531 (2021)
Volume 22
Issue 12
International Journal of Molecular Sciences, 22, 12
International Journal of Molecular Sciences, 22
International Journal of Molecular Sciences, Vol 22, Iss 6531, p 6531 (2021)
Volume 22
Issue 12
International Journal of Molecular Sciences, 22, 12
Inflammasomes are powerful cytosolic sensors of environmental stressors and are critical for triggering interleukin-1 (IL-1)-mediated inflammatory responses. However, dysregulation of inflammasome activation may lead to pathological conditions, and t