Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Maria Adelaida Gómez"'
Autor:
Maria Del Mar Castro, Isabella Caicedo, Helen Johanna Ortiz-Rojas, Carmen Manuela Castillo, Adriana Giovanna Medina, Neal Alexander, Maria Adelaida Gómez, Ludwig L Albornoz
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256566 (2021)
BackgroundAdequate testing is critically important for control of the SARS-CoV-2 pandemic. Antibody testing is an option for case management and epidemiologic studies, with high specificity and variable sensitivity. However, characteristics of local
Externí odkaz:
https://doaj.org/article/c47df0792b414c7cb5fafb5ee5ff5838
Autor:
Ivo B. Regli, Olga Lucía Fernández, Berenice Martínez-Salazar, Maria Adelaida Gómez, Nancy Gore Saravia, Fabienne Tacchini-Cottier
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Leishmania (Viannia) panamensis (L. (V.) p.) is the main causative agent of cutaneous leishmaniasis in Colombia and is usually treated with either meglumine antimoniate (MA) or miltefosine (MIL). In recent years, there has been increasing evidence of
Externí odkaz:
https://doaj.org/article/aec5cb531de643568f3357500a252cc4
Autor:
Deninson Alejandro Vargas, David J. Gregory, Roni Nitzan Koren, Dan Zilberstein, Ashton Trey Belew, Najib M. El-Sayed, María Adelaida Gómez
Publikováno v:
Frontiers in Parasitology, Vol 2 (2023)
Host cell functions that participate in the pharmacokinetics and pharmacodynamics (PK/PD) of drugs against intracellular pathogen infections are critical for drug efficacy. In this study, we investigated whether macrophage mechanisms of xenobiotic de
Externí odkaz:
https://doaj.org/article/3a3e86c308f74579b3e15cd09ab1ca59
Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-11 (2022)
Abstract Background Colombia is ranked very high among countries with the highest numbers of endemic Leishmania species (n = 9) causing human disease. Although much effort has been devoted to generating simple and specific tools for Leishmania specie
Externí odkaz:
https://doaj.org/article/291ebb602efe49ab92666cdda36bc5c8
Publikováno v:
Wellcome Open Research, Vol 7 (2023)
Background: Obtaining high quality RNA from skin biopsies is complex due the physical composition and high content of nucleases of this tissue. This becomes particularly challenging when using compromised skin samples with necrotic, inflammed or dama
Externí odkaz:
https://doaj.org/article/4fd1e067ef6b4a02b98a14d80e00906d
Autor:
Maria Adelaida Gomez, Ashton Trey Belew, Adriana Navas, Mariana Rosales-Chilama, Julieth Murillo, Laura A. L. Dillon, Theresa A. Alexander, Alvaro Martinez-Valencia, Najib M. El-Sayed
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Early host-pathogen interactions drive the host response and shape the outcome of natural infections caused by intracellular microorganisms. These interactions involve a number of immune and non-immune cells and tissues, along with an assortment of h
Externí odkaz:
https://doaj.org/article/ff4683e6cbf740a4babeead0373c1464
Autor:
Adriana Navas, Lina Giraldo-Parra, Miguel Darío Prieto, Juliana Cabrera, María Adelaida Gómez
Publikováno v:
BMC Immunology, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Human peripheral blood mononuclear cells (PBMCs) are extensively used for research of immune cell functions, identification of biomarkers and development of diagnostics and therapeutics for human diseases, among others. The assump
Externí odkaz:
https://doaj.org/article/b0164ab2becc4510bc1b283b5bb8f5d6
Autor:
Maria del Mar Castro, Alexandra Cossio, Adriana Navas, Olga Fernandez, Liliana Valderrama, Lyda Cuervo-Pardo, Ricardo Marquez-Oñate, María Adelaida Gómez, Nancy Gore Saravia
Publikováno v:
Pathogens, Vol 11, Iss 3, p 378 (2022)
Addition of the immunomodulator pentoxifylline (PTX) to antimonial treatment of mucosal leishmaniasis has shown increased efficacy. This randomized, double-blind, placebo-controlled trial evaluated whether addition of pentoxifylline to meglumine anti
Externí odkaz:
https://doaj.org/article/ad40c693575e4c2f813d66c2bd58e19d
Autor:
Deninson Alejandro Vargas, Miguel Dario Prieto, Alvaro José Martínez-Valencia, Alexandra Cossio, Karl E. V. Burgess, Richard J.S. Burchmore, María Adelaida Gómez
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Control of cutaneous leishmaniasis (CL) in the Americas is dependent on chemotherapy with parenteral pentavalent antimonials. High rates of treatment failure urge the search for predictive and prognostic markers of therapeutic responsiveness. In this
Externí odkaz:
https://doaj.org/article/8f2d52434058407c80a3373ff9012b82
Autor:
Alvaro J Martínez-Valencia, Carlos Frisherald Daza-Rivera, Mariana Rosales-Chilama, Alexandra Cossio, Elkin J Casadiego Rincón, Mayur M Desai, Nancy Gore Saravia, María Adelaida Gómez
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 7, p e0005713 (2017)
The determinants of parasite persistence or elimination after treatment and clinical resolution of cutaneous leishmaniasis (CL) are unknown. We investigated clinical and parasitological parameters associated with the presence and viability of Leishma
Externí odkaz:
https://doaj.org/article/22d38178b3bb418e974c903265adf9f9