IL6 Signaling in Peripheral Blood T Cells Predicts Clinical Outcome in Breast Cancer

Autor: James Waisman, Carrie Wang, Diana L. Simons, Xuyang Lu, John H. Yim, Vernon C. Maino, Maria A. Suni, Andrea K. Miyahira, Peter P. Lee, Lei Wang, Frederick M. Dirbas, Andrew Y. Chang

Publikováno v: Cancer Research. 77:1119-1126

IL6 is a pleiotropic cytokine with both pro- and anti-inflammatory properties, which acts directly on cancer cells to promote their survival and proliferation. Elevated serum IL6 levels negatively correlate with survival of cancer patients, which is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf710ed49b90186d14055cc12af03e5
https://doi.org/10.1158/0008-5472.can-16-1373

CD4+CD8dim T lymphocytes exhibit enhanced cytokine expression, proliferation and cytotoxic activity in response to HCMV and HIV-1 antigens

Autor: Louis J. Picker, Holden T. Maecker, David W. Houck, Ronald B. Moss, Susan B. Wormsley, Smita Ghanekar, Vernon C. Maino, Maria A. Suni

Publikováno v: European Journal of Immunology. 31:2512-2520

CD4(+)CD8(dim) T cells represent a minor subset of the total CD3(+) T cell population in peripheral blood. Although transient and persistent expansions of these cells have been reported in both healthy and diseased individuals, the functional propert

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74e738de9dbaf64c662b5302e99f814c
https://doi.org/10.1002/1521-4141(200108)31:8<2512::aid-immu2512>3.0.co

Chronic HIV infection enhances the responsiveness of antigen presenting cells to commensal Lactobacillus

Autor: Monica Macal, Maria A. Suni, William K. Hu, Christopher A. Gaulke, Sumathi Sankaran-Walters, Richard B. Pollard, Satya Dandekar, Irina Grishina, Lauren H. Nagy, Lauren A. Hirao, Smita Ghanekar, Jennifer Brown, Maria L. Marco, Andreas J. Bäumler

Publikováno v: PloS one, vol 8, iss 8
PLoS ONE
Nagy, LH; Grishina, I; Macal, M; Hirao, LA; Hu, WK; Sankaran-Walters, S; et al.(2013). Chronic HIV Infection Enhances the Responsiveness of Antigen Presenting Cells to Commensal Lactobacillus. PLoS ONE, 8(8). doi: 10.1371/journal.pone.0072789. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/6qs5m9m6
PLoS ONE, Vol 8, Iss 8, p e72789 (2013)

Chronic immune activation despite long-term therapy poses an obstacle to immune recovery in HIV infection. The role of antigen presenting cells (APCs) in chronic immune activation during HIV infection remains to be fully determined. APCs, the frontli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68477ddf7d38b7c084f814435d12d02
https://escholarship.org/uc/item/6qs5m9m6

Rapid flow cytometric method for measuring lymphocyte subset activation

Autor: Maria A. Suni, Vernon C. Maino, Joyce J. Ruitenberg

Publikováno v: Cytometry. 20:127-133

Standard in vitro methods for assessing T-cell activation have typically measured either the proliferative responses of peripheral blood mononuclear cell (PBMC) cultures to various provocative stimuli employing tritiated thymidine incorporation or th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0d545fb12109cc521323952a5eaf99
https://doi.org/10.1002/cyto.990200205

Flow Cytometric Analysis of Cell Signaling Proteins

Autor: Vernon C. Maino, Maria A. Suni

Publikováno v: Methods in Molecular Biology ISBN: 9781617790232

In recent years, techniques that combine the use of phospho-specific antibodies and multiparameter flow cytometry have been developed for the detection of protein phosphorylation at the single cell level. Flow cytometry is uniquely suited for this ty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::709e55894ab4337e23fc545bb73e1028
https://doi.org/10.1007/978-1-61779-024-9_9